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Critical Reviews™ in Eukaryotic Gene Expression

Publication de 6  numéros par an

ISSN Imprimer: 1045-4403

ISSN En ligne: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Molecular Mechanisms Mediating Axon Pathway Formation

Volume 7, Numéro 1-2, 1997, pp. 95-116
DOI: 10.1615/CritRevEukarGeneExpr.v7.i1-2.60
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RÉSUMÉ

During nervous system formation nerve cells extend axons in order to form precise patterns of neuronal connectivity. These connections are often established after the neuronal growth cones have pioneered or navigated through complex pathways to their target area both within the CNS and to and from the periphery. Recent studies have provided evidence that the process of specific pathway formation may rely on a number of molecular guidance mechanisms and cues such as selective adhesion, growth cone avoidance, surface gradients, guidepost cells, and chemotropism. Analysis of the molecular basis for these guidance mechanisms show that the molecules involved often belong to distinct multigene families and that they can provide both short- and long-range attractive as well as repulsive cues. Many of these molecules have a modular structure that is made up of different tandemly arranged domains that allow for multiple functional interactions with a range of other molecules. This allows the same molecule to be multifunctional, for example, by attracting certain neurons while repelling others. This review is an overview of the molecular structure, as it relates to function and mechanisms of action of some of the major gene families thought to be mediating specific axonal guidance and pathway formation.

CITÉ PAR
  1. Shubayev Veronica I., Myers Robert R., Matrix metalloproteinase-9 promotes nerve growth factor-induced neurite elongation but not new sprout formation in vitro, Journal of Neuroscience Research, 77, 2, 2004. Crossref

  2. Martinez Veronica G., Menger Gus J., Zoran Mark J., Regeneration and asexual reproduction share common molecular changes: upregulation of a neural glycoepitope during morphallaxis in Lumbriculus, Mechanisms of Development, 122, 5, 2005. Crossref

  3. Jie Chunfa, Xu Yingzhi, Wang Dong, Lukin Dana, Zipser Birgit, Jellies John, Johansen Kristen M, Johansen Jørgen, Posttranslational processing and differential glycosylation of Tractin, an Ig-superfamily member involved in regulation of axonal outgrowth, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1479, 1-2, 2000. Crossref

  4. Jie Chunfa, Zipser Birgit, Jellies John, Johansen Kristen M, Johansen Jørgen, Differential glycosylation and proteolytical processing of LeechCAM in central and peripheral leech neurons, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1452, 2, 1999. Crossref

  5. Huang Yueqiao, Jellies John, Johansen Kristen M., Johansen Jørgen, Differential Glycosylation of Tractin and LeechCAM, Two Novel Ig Superfamily Members, Regulates Neurite Extension and Fascicle Formation, Journal of Cell Biology, 138, 1, 1997. Crossref

  6. Xu Ying-Zhi, Ji Yun, Zipser Birgit, Jellies John, Johansen Kristen M., Johansen Jørgen, Proteolytic Cleavage of the Ectodomain of the L1 CAM Family Member Tractin, Journal of Biological Chemistry, 278, 6, 2003. Crossref

  7. Comi Giancarlo, The physiopathology of multiple sclerosis, in Multiple Sclerosis, 2010. Crossref

  8. Basic mechanisms, in Multiple Sclerosis, 2010. Crossref

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