Publication de 6 numéros par an
ISSN Imprimer: 1045-4403
ISSN En ligne: 2162-6502
Indexed in
Regulatory Controls for Osteoblast Growth and Differentiation: Role of Runx/Cbfa/AML Factors
RÉSUMÉ
Formation of skeletal elements during embryogenesis and the dynamic remodeling of bone in the adult involve an exquisite interplay of developmental cues, signaling proteins, transcription factors, and their coregulatory proteins that support differentiation of osteogenic lineage cells from the initial mesenchymal progenitor cell to the mature osteocyte in mineralized connective tissue. As regulatory factors continue to be identified, the complexity of the molecular mechanisms that control gene expression in osteoblast lineage cells and drive the osteoblast maturation process are being further appreciated. A central regulator of bone formation is the Runx2 (Cbfa1/AML3) transcription factor which fulfills its role as a master regulatory switch through unique properties for mediating the temporal activation and/or repression of cell growth and phenotypic genes as osteoblasts progress through stages of differentiation. This review examines the multifunctional roles of Runx2 during osteogenesis. Runx2 functions as a "platform protein" that interacts with a spectrum of coregulatory proteins to provide a combinatorial mechanism for integrating cell signaling pathways required for osteoblast differentiation and the tissue-specific regulation of gene expression. In a broader context, it has recently been appreciated that the Runx1 hematopoietic factor and the Runx3 gene associated with neural and gut development are also expressed in the skeleton, although at present our knowledge of their roles in bone formation is limited. Here we discuss the biological functions of Runx factors in promoting cell fate determination and lineage progression, which include (1) regulating gene activation and repression through coregulatory protein interactions and by supporting chromatin remodeling; (2) integrating ECM signaling and cues from developmental, hormonal, and signal transduction pathways by formation of complexes organized in subnuclear domains; and (3) mediating cell growth control. Last, a comprehensive understanding of Runx functions in the skeleton must consider the regulatory mechanisms that control Runx2 transcription and its functional activity through posttranslational modifications.
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Kwok Sukyee, Partridge Nicola C., Srinivasan Narasaimhan, Nair Shantikumar V., Selvamurugan Nagarajan, Mitogen activated protein kinase-dependent inhibition of osteocalcin gene expression by transforming growth factor-β1, Journal of Cellular Biochemistry, 106, 1, 2009. Crossref
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Jäger M., Sager M., Knipper A., Degistirici Ö., Fischer J., Kögler G., Wernet P., Krauspe R., In-vitro- und In-vivo-Knochenregenerierung durch mesenchymale Stammzellen aus dem Nabelschnurblut, Der Orthopäde, 33, 12, 2004. Crossref
-
Wein Marc N., Jones Dallas C., Glimcher Laurie H., Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity, Immunological Reviews, 208, 1, 2005. Crossref
-
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-
Holz Jonathan D., Sheu Tzong-jen, Drissi Hicham, Matsuzawa Mitsuhiro, Zuscik Michael J., Puzas J. Edward, Environmental agents affect skeletal growth and development, Birth Defects Research Part C: Embryo Today: Reviews, 81, 1, 2007. Crossref
-
Macsai Carmen E., Foster Bruce K., Xian Cory J., Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair, Journal of Cellular Physiology, 215, 3, 2008. Crossref
-
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-
Zhang Chenying, Zheng Shuguo, Wang Yixiang, Zhao Yuming, Zhu Junxia, Ge Lihong, Mutational analysis of RUNX2 gene in Chinese patients with cleidocranial dysplasia, Mutagenesis, 25, 6, 2010. Crossref
-
Flores Maria Vega, Lam Enid Yi Ni, Crosier Philip, Crosier Kathryn, A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish, Developmental Dynamics, 235, 11, 2006. Crossref
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Trentz O. A., Arikketh D., Sentilnathan V., Hemmi S., Handschin A. E., de Rosario B., Mohandas P., Mohandas P. V. A., Surface proteins and osteoblast markers: characterization of human adipose tissue-derived osteogenic cells, European Journal of Trauma and Emergency Surgery, 36, 5, 2010. Crossref
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-
Zagami Chrissandra J., Zusso Morena, Stifani Stefano, Runx transcription factors: Lineage-specific regulators of neuronal precursor cell proliferation and post-mitotic neuron subtype development, Journal of Cellular Biochemistry, 107, 6, 2009. Crossref
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Chen J.B., Yu Y., Yang J-L., Morgan D.A.F., Walsh W.R., BMP-7 and CBFA1 in allograft bonein vivo bone formation and the influence of γ-irradiation, Journal of Biomedical Materials Research Part A, 80A, 2, 2007. Crossref
-
Pereira Clifford T., Huang Weibiao, Jarrahy Reza, Rudkin George, Yamaguchi Dean T., Miller Timothy A., Human and Mouse Osteoprogenitor Cells Exhibit Distinct Patterns of Osteogenesis in Three-Dimensional Tissue Engineering Scaffolds, Plastic and Reconstructive Surgery, 124, 6, 2009. Crossref
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-
Shur I., Socher R., Benayahu D., In vivo association of CReMM/CHD9 with promoters in osteogenic cells, Journal of Cellular Physiology, 207, 2, 2006. Crossref
-
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Thomas David, Kansara Maya, Epigenetic modifications in osteogenic differentiation and transformation, Journal of Cellular Biochemistry, 98, 4, 2006. Crossref
-
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Kim Hyo-Jin, Nam Soon-Hyeun, Kim Hyun-Jung, Park Hyo-Sang, Ryoo Hyun-Mo, Kim Shin-Yoon, Cho Tae-Joon, Kim Seung-Gon, Bae Suk-Chul, Kim In-San, Stein Janet L., van Wijnen Andre J., Stein Gary S., Lian Jane B., Choi Je-Yong, Four novelRUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype, Journal of Cellular Physiology, 207, 1, 2006. Crossref
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-
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Kanno Takahiro, Takahashi Tetsu, Tsujisawa Toshiyuki, Ariyoshi Wataru, Nishihara Tatsuji, Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts, Journal of Cellular Biochemistry, 101, 5, 2007. Crossref
-
Gordeladze Jan O, Djouad Farida, Brondello Jean-Marc, Noël Daniele, Duroux-Richard Isabelle, Apparailly Florence, Jorgensen Christian, Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs, Acta Pharmacologica Sinica, 30, 10, 2009. Crossref
-
Song Shu Jun, Cool Simon M., Nurcombe Victor, Regulated expression of syndecan-4 in rat calvaria osteoblasts induced by fibroblast growth factor-2, Journal of Cellular Biochemistry, 100, 2, 2007. Crossref
-
Seriwatanachai Dutmanee, Krishnamra Nateetip, van Leeuwen J.P.T.M., Evidence for direct effects of prolactin on human osteoblasts: Inhibition of cell growth and mineralization, Journal of Cellular Biochemistry, 107, 4, 2009. Crossref
-
Kozhevnikova M. N., Mikaelyan A. S., Starostin V. I., Molecular and genetic regulation of osteogenic differentiation of mesenchymal stromal cells, Biology Bulletin, 35, 3, 2008. Crossref
-
Pratap J., Lian J. B., Javed A., Barnes G. L., van Wijnen A. J., Stein J. L., Stein G. S., Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone, Cancer and Metastasis Reviews, 25, 4, 2006. Crossref
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Pockwinse Shirwin M., Rajgopal Arun, Young Daniel W., Mujeeb Khwaja A., Nickerson Jeffrey, Javed Amjad, Redick Sambra, Lian Jane B., van Wijnen Andre J., Stein Janet L., Stein Gary S., Doxsey Stephen J., Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2, Journal of Cellular Physiology, 206, 2, 2006. Crossref
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Nathan Saminathan S., Pereira Barry P., Zhou Ye-fang, Gupta Anurag, Dombrowski Christian, Soong Ritchie, Pho Robert W. H., Stein Gary S., Salto-Tellez Manuel, Cool Simon M., van Wijnen Andre J., Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma, Molecular Biology Reports, 36, 1, 2009. Crossref
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Zaidi Sayyed K., Javed Amjad, Pratap Jitesh, Schroeder Tania M., Westendorf Jennifer J., Lian Jane B., van Wijnen Andre J., Stein Gary S., Stein Janet L., Alterations in intranuclear localization of Runx2 affect biological activity, Journal of Cellular Physiology, 209, 3, 2006. Crossref
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Rajgopal Arun, Young Daniel W., Mujeeb Khawaja A., Stein Janet L., Lian Jane B., van Wijnen Andre J., Stein Gary S., Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells, Journal of Cellular Biochemistry, 100, 6, 2007. Crossref
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Lou Y., Javed A., Hussain S., Colby J., Frederick D., Pratap J., Xie R., Gaur T., van Wijnen A. J., Jones S. N., Stein G. S., Lian J. B., Stein J. L., A Runx2 threshold for the cleidocranial dysplasia phenotype, Human Molecular Genetics, 18, 3, 2008. Crossref
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Bab I, Zimmer A, Cannabinoid receptors and the regulation of bone mass, British Journal of Pharmacology, 153, 2, 2008. Crossref
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Jackson Rebecca A., Murali Sadasivam, van Wijnen Andre J., Stein Gary S., Nurcombe Victor, Cool Simon M., Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2, Journal of Cellular Physiology, 210, 1, 2007. Crossref
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Fromigué O, Haÿ E, Modrowski D, Bouvet S, Jacquel A, Auberger P, Marie P J, RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation, Cell Death & Differentiation, 13, 11, 2006. Crossref
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Zaidi Sayyed K., Young Daniel W., Javed Amjad, Pratap Jitesh, Montecino Martin, van Wijnen Andre, Lian Jane B., Stein Janet L., Stein Gary S., Nuclear microenvironments in biological control and cancer, Nature Reviews Cancer, 7, 6, 2007. Crossref
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Bae Jong-Sup, Gutierrez Soraya, Narla Radhika, Pratap Jitesh, Devados Rajitha, van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., Javed Amjad, Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation, Journal of Cellular Biochemistry, 100, 2, 2007. Crossref
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-
Hill David A., Imbalzano Anthony N., HMGN1 is dispensable for myogenesis and adipogenesis, Gene, 371, 1, 2006. Crossref
-
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Rath Bjoern, Nam Jin, Knobloch Thomas J., Lannutti John J., Agarwal Sudha, Compressive forces induce osteogenic gene expression in calvarial osteoblasts, Journal of Biomechanics, 41, 5, 2008. Crossref
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Araujo Ana Paula B., Ribeiro Maria Emília O.B., Ricci Ritchelli, Torquato Ricardo J., Toma Leny, Porcionatto Marimélia A., Glial cells modulate heparan sulfate proteoglycan (HSPG) expression by neuronal precursors during early postnatal cerebellar development, International Journal of Developmental Neuroscience, 28, 7, 2010. Crossref
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Stein Gary S., Zaidi Sayyed K., Stein Janet L., Lian Jane B., van Wijnen Andre J., Montecino Martin, Young Daniel W., Javed Amjad, Pratap Jitesh, Choi Je-Yong, Ali Syed A., Pande Sandhya, Hassan Mohammad Q., Transcription-factor-mediated epigenetic control of cell fate and lineage commitmentThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process., Biochemistry and Cell Biology, 87, 1, 2009. Crossref
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Carvallo Loreto, Henriquez Berta, Olate Juan, van Wijnen Andre J., Lian Jane B., Stein Gary S., Onate Sergio, Stein Janet L., Montecino Martin, The 1α,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene, The Journal of Steroid Biochemistry and Molecular Biology, 103, 3-5, 2007. Crossref
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Javed Amjad, Chen Haiyan, Ghori Farah Y., Genetic and Transcriptional Control of Bone Formation, Oral and Maxillofacial Surgery Clinics of North America, 22, 3, 2010. Crossref
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Bensamoun Sabine F., Hawse John R., Subramaniam Malayannan, Ilharreborde Brice, Bassillais Armelle, Benhamou Claude L., Fraser Daniel G., Oursler Merry J., Amadio Peter C., An Kai-Nan, Spelsberg Thomas C., TGFβ inducible early gene-1 knockout mice display defects in bone strength and microarchitecture, Bone, 39, 6, 2006. Crossref
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BALDINI N., CENNI E., CIAPETTI G., GRANCHI D., SAVARINO L., Bone repair and regeneration, in Bone Repair Biomaterials, 2009. Crossref
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Montecino Martin, Stein Janet L., Stein Gary S., Lian Jane B., van Wijnen Andre J., Cruzat Fernando, Gutiérrez Soraya, Olate Juan, Marcellini Sylvain, Gutiérrez José L., Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequenceThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosomes Conference, and has undergone the Journal's usual peer review process., Biochemistry and Cell Biology, 85, 4, 2007. Crossref
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Kärner Elerin, Unger Christian, Sloan Alastair J., Ährlund-Richter Lars, Sugars Rachael V., Wendel Mikael, Bone Matrix Formation in Osteogenic Cultures Derived from Human Embryonic Stem Cells in Vitro, Stem Cells and Development, 16, 1, 2007. Crossref
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Tai Guangping, Christodoulou Ioannis, Bishop Anne E., Polak Julia M., Use of green fluorescent fusion protein to track activation of the transcription factor osterix during early osteoblast differentiation, Biochemical and Biophysical Research Communications, 333, 4, 2005. Crossref
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Guo Juanli, Padilla Ricardo J., Ambrose Wallace, De Kok Ingeborg J., Cooper Lyndon F., The effect of hydrofluoric acid treatment of TiO2 grit blasted titanium implants on adherent osteoblast gene expression in vitro and in vivo, Biomaterials, 28, 36, 2007. Crossref
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Henriquez Berta, Hepp Matias, Merino Paola, Sepulveda Hugo, van Wijnen Andre J., Lian Jane B., Stein Gary S., Stein Janet L., Montecino Martin, C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells, Journal of Cellular Physiology, 226, 11, 2011. Crossref
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Aghaloo Tara, Cowan Catherine M., Chou Yu-Fen, Zhang Xinli, Lee Haofu, Miao Steve, Hong Nichole, Kuroda Shun'ichi, Wu Benjamin, Ting Kang, Soo Chia, Nell-1-Induced Bone Regeneration in Calvarial Defects, The American Journal of Pathology, 169, 3, 2006. Crossref
-
Das Kakoli, Leong David Tai, Gupta Anurag, Shen Liang, Putti Thomas, Stein Gary S., van Wijnen Andre J., Salto-Tellez Manuel, Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer, European Journal of Cancer, 45, 13, 2009. Crossref
-
Fazenda Cindy, Simões Brigite, Kelsh Robert N., Cancela M. Leonor, Conceição Natércia, Dual transcriptional regulation by runx2 of matrix Gla protein in Xenopus laevis, Gene, 450, 1-2, 2010. Crossref
-
Guo Xiangfei, Yang Weihong, Ni Jiaxiang, He Mingwei, Yang Liqiang, A role for suppressed bone formation favoring catch-up fat in the pathophysiology of catch-up growth after food restriction, European Journal of Nutrition, 50, 8, 2011. Crossref
-
Li Jie-li, Cui Bin, Qi Li, Li Xiao-ying, Deng Lian-fu, Ning Guang, Liu Jian-min, NMDA enhances stretching-induced differentiation of osteobalsts through the ERK1/2 signaling pathway, Bone, 43, 3, 2008. Crossref
-
Levy Matthew E., Parker Robert A., Ferrell Robert E., Zmuda Joseph M., Greenspan Susan L., Farnesyl diphosphate synthase: A novel genotype association with bone mineral density in elderly women, Maturitas, 57, 3, 2007. Crossref
-
Mathews S., Gupta P. K., Bhonde R., Totey S., Chitosan enhances mineralization during osteoblast differentiation of human bone marrow-derived mesenchymal stem cells, by upregulating the associated genes, Cell Proliferation, 44, 6, 2011. Crossref
-
Stein Gary S., Stein Janet L., van Wijnen Andre J., Lian Jane B., Zaidi Sayyed K., Nickerson Jeffrey A., Montecino Martin A., Young Daniel W., An architectural genetic and epigenetic perspective, Integr. Biol., 3, 4, 2011. Crossref
-
Mehrotra Meenal, Saegusa Masatomo, Voznesensky Olga, Pilbeam Carol, Role of Cbfa1/Runx2 in the fluid shear stress induction of COX-2 in osteoblasts, Biochemical and Biophysical Research Communications, 341, 4, 2006. Crossref
-
Hsieh Tsai-Pei, Sheu Shiow-Yunn, Sun Jui-Sheng, Chen Ming-Hong, Liu Man-Hai, Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression, Phytomedicine, 17, 6, 2010. Crossref
-
Decaris Martin L., Leach J. Kent, Design of Experiments Approach to Engineer Cell-Secreted Matrices for Directing Osteogenic Differentiation, Annals of Biomedical Engineering, 39, 4, 2011. Crossref
-
Woei Ng Kee, Speicher Tobias, Dombrowski Christian, Helledie Torben, Haupt Larisa M., Nurcombe Victor, Cool Simon M., Osteogenic Differentiation of Murine Embryonic Stem Cells is Mediated by Fibroblast Growth Factor Receptors, Stem Cells and Development, 16, 2, 2007. Crossref
-
Corry Gareth N, Underhill D Alan, Subnuclear compartmentalization of sequence-specific transcription factors and regulation of eukaryotic gene expression, Biochemistry and Cell Biology, 83, 4, 2005. Crossref
-
Crespi Roberto, Mariani Elisabetta, Benasciutti Elisa, Capparè Paolo, Cenci Simone, Gherlone Enrico, Magnesium-Enriched Hydroxyapatite Versus Autologous Bone in Maxillary Sinus Grafting: Combining Histomorphometry With Osteoblast Gene Expression Profiles Ex Vivo, Journal of Periodontology, 80, 4, 2009. Crossref
-
Dalle Carbonare Luca, Innamorati Giulio, Valenti Maria Teresa, Transcription Factor Runx2 and its Application to Bone Tissue Engineering, Stem Cell Reviews and Reports, 8, 3, 2012. Crossref
-
LIAN JANE B., STEIN GARY S., The Cells of Bone, in Dynamics of Bone and Cartilage Metabolism, 2006. Crossref
-
Ugarte Giorgia D., Opazo Tatiana, Leisewitz Francisco, van Zundert Brigitte, Montecino Martin, Runx1 and C/EBPβ transcription factors directly up-regulate P2X3 gene transcription, Journal of Cellular Physiology, 227, 4, 2012. Crossref
-
Zaidi Sayyed K., Trombly Daniel J., Dowdy Christopher R., Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Epigenetic mechanisms in leukemia, Advances in Biological Regulation, 52, 3, 2012. Crossref
-
DEMPSTER DAVID W., ZHOU HUA, New Concepts in Bone Remodeling, in Dynamics of Bone and Cartilage Metabolism, 2006. Crossref
-
Fromigué Olivia, Brun Julia, Marty Caroline, Da Nascimento Sophie, Sonnet Pascal, Marie Pierre J., Peptide-based activation of alpha5 integrin for promoting osteogenesis, Journal of Cellular Biochemistry, 113, 9, 2012. Crossref
-
Selvamurugan Nagarajan, Shimizu Emi, Lee Minnkyong, Liu Tong, Li Hong, Partridge Nicola C., Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation, FEBS Letters, 583, 7, 2009. Crossref
-
Pereira Barry P., Zhou Yefang, Gupta Anurag, Leong David T., Aung Khin Zarchi, Ling Ling, Pho Robert W.H., Galindo Mario, Salto-Tellez Manuel, Stein Gary S., Cool Simon M., van Wijnen Andre J., Nathan Saminathan S., Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1), Journal of Cellular Physiology, 221, 3, 2009. Crossref
-
Dong Yu-Feng, Soung Do Y., Schwarz Edward M., O'Keefe Regis J., Drissi Hicham, Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor, Journal of Cellular Physiology, 208, 1, 2006. Crossref
-
Montecino Martin, Stein Gary S., Cruzat Fernando, Marcellini Sylvain, Stein Janet L., Lian Jane B., van Wijnen Andre J., Arriagada Gloria, An architectural perspective of vitamin D responsiveness, Archives of Biochemistry and Biophysics, 460, 2, 2007. Crossref
-
Marie Pierre J., Transcription factors controlling osteoblastogenesis, Archives of Biochemistry and Biophysics, 473, 2, 2008. Crossref
-
Chen Pei-Yu, Sun Jui-Sheng, Tsuang Yang-Hwei, Chen Ming-Hong, Weng Pei-Wei, Lin Feng-Huei, Simvastatin promotes osteoblast viability and differentiation via Ras/Smad/Erk/BMP-2 signaling pathway, Nutrition Research, 30, 3, 2010. Crossref
-
Stein Gary S., Lian Jane B., Montecino Martin, van Wijnen J., Stein Janet L., Javed Amjad, Young Daniel W., Hassan Mohammad Q., Zaidi Sayyed K., Skeletal Gene Expression in Nuclear Microenvironments, in Principles of Bone Biology, 2008. Crossref
-
Lu Li, Wu Liang, Jia Huanhuan, Li Yingbing, Chen Jun, Xu Duorong, Li Qingnan, The epithelial sodium channel is involved in dexamethasone-induced osteoblast differentiation and mineralization, Cell Biology and Toxicology, 28, 5, 2012. Crossref
-
Chen Jianfeng, Yuan Kaiyu, Mao Xia, Miano Joseph M, Wu Hui, Chen Yabing, Serum response factor regulates bone formation via IGF-1 and Runx2 signals, Journal of Bone and Mineral Research, 27, 8, 2012. Crossref
-
Hempel U., Möller S., Noack C., Hintze V., Scharnweber D., Schnabelrauch M., Dieter P., Sulfated hyaluronan/collagen I matrices enhance the osteogenic differentiation of human mesenchymal stromal cells in vitro even in the absence of dexamethasone, Acta Biomaterialia, 8, 11, 2012. Crossref
-
Robaszkiewicz Agnieszka, Erdélyi Katalin, Kovács Katalin, Kovács István, Bai Péter, Rajnavölgyi Éva, Virág László, Hydrogen peroxide-induced poly(ADP-ribosyl)ation regulates osteogenic differentiation-associated cell death, Free Radical Biology and Medicine, 53, 8, 2012. Crossref
-
Przybylowski Colin, Quinn Therese, Callahan Alyson, Kaplan Max, Golding Anne, Alesi Christopher, Ammar Mohamed, LeBlon Courtney E., Guo Yan, Zhang Xiaohui, Jedlicka Sabrina S., MC3T3 preosteoblast differentiation on bone morphogenetic protein-2 peptide ormosils, Journal of Materials Chemistry, 22, 21, 2012. Crossref
-
OTSUKA Fukunaga, KATAOKA Yu, MIYAZAKI Takashi, Enhanced osteoblast response to electrical discharge machining surface, Dental Materials Journal, 31, 2, 2012. Crossref
-
Varelas Xaralabos, Wrana Jeffrey L., Coordinating developmental signaling: novel roles for the Hippo pathway, Trends in Cell Biology, 22, 2, 2012. Crossref
-
He Pengfei, Sahoo Sambit, Ng Kian Siang, Chen Kelei, Toh Siew Lok, Goh James Cho Hong, Enhanced osteoinductivity and osteoconductivity through hydroxyapatite coating of silk-based tissue-engineered ligament scaffold, Journal of Biomedical Materials Research Part A, 101A, 2, 2013. Crossref
-
Hovhannisyan Hayk, Zhang Ying, Hassan Mohammad Q., Wu Hai, Glackin Carlotta, Lian Jane B., Stein Janet L., Montecino Martin, Stein Gary S., van Wijnen Andre J., Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene, Journal of Cellular Physiology, 228, 2, 2013. Crossref
-
Boumah Christine E., Selvamurugan Nagarajan, Partridge Nicola C., , 80, 2005. Crossref
-
Riksen Elisabeth A., Petzold Christiane, Brookes Steven, Lyngstadaas Ståle P., Reseland Janne E., Human osteoblastic cells discriminate between 20-kDa amelogenin isoforms, European Journal of Oral Sciences, 119, 2011. Crossref
-
Baddour Joëlle A., Sousounis Konstantinos, Tsonis Panagiotis A., Organ repair and regeneration: An overview, Birth Defects Research Part C: Embryo Today: Reviews, 96, 1, 2012. Crossref
-
Ugarte Giorgia D., Diaz Emilio, Biscaia Miguel, Stehberg Jimmy, Montecino Martin, van Zundert Brigitte, Transcription of the pain-related TRPV1 gene requires Runx1 and C/EBPβ factors, Journal of Cellular Physiology, 228, 4, 2013. Crossref
-
Stein Gary S., Lian Jane B., van Wijnen Andre J., Stein Janet L., Javed Amjad, Montecino Martin, Choi Je-Yong, Vradii Diana, Zaidi Sayyed K., Pratap Jitesh, Young Daniel, Organization of transcriptional regulatory machinery in nuclear microenvironments: Implications for biological control and cancer, Advances in Enzyme Regulation, 47, 1, 2007. Crossref
-
Lee Sung Ho, Choi You Hee, Kim Yeon-Jin, Choi Hong Seok, Yeo Chang-Yeol, Lee Kwang Youl, Prolyl isomerase Pin1 enhances osteoblast differentiation through Runx2 regulation, FEBS Letters, 587, 22, 2013. Crossref
-
Shu Lei, Zhang Hengwei, Boyce Brendan F, Xing Lianping, Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration, Journal of Bone and Mineral Research, 28, 9, 2013. Crossref
-
Koo Ki-Tae, Lee Suk W., Lee Myung-Hyun, Kim Kyung H., Jung Su H., Kang Yoon G., Time-dependent expression of osteoblast marker genes in human primary cells cultured on microgrooved titanium substrata, Clinical Oral Implants Research, 25, 6, 2014. Crossref
-
Boccafoschi Francesca, Mosca Cecilia, Ramella Martina, Valente Guido, Cannas Mario, The effect of mechanical strain on soft (cardiovascular) and hard (bone) tissues, Cell Adhesion & Migration, 7, 2, 2013. Crossref
-
Chitteti Brahmananda R., Cheng Ying-Hua, Kacena Melissa A., Srour Edward F., Hierarchical organization of osteoblasts reveals the significant role of CD166 in hematopoietic stem cell maintenance and function, Bone, 54, 1, 2013. Crossref
-
Shi Kaikai, Lu Jianlei, Zhao Yue, Wang Lintao, Li Ji, Qi Bing, Li Hongwei, Ma Changyan, MicroRNA-214 suppresses osteogenic differentiation of C2C12 myoblast cells by targeting Osterix, Bone, 55, 2, 2013. Crossref
-
Kim Jiseon, Yang Jihyun, Park Ok-Jin, Kang Seok-Seong, Kim Woo-Shin, Kurokawa Kenji, Yun Cheol-Heui, Kim Hong-Hee, Lee Bok Luel, Han Seung Hyun, Lipoproteins are an important bacterial component responsible for bone destruction through the induction of osteoclast differentiation and activation, Journal of Bone and Mineral Research, 28, 11, 2013. Crossref
-
Titorencu Irina, Pruna Vasile, Jinga Victor V., Simionescu Maya, Osteoblast ontogeny and implications for bone pathology: an overview, Cell and Tissue Research, 355, 1, 2014. Crossref
-
Marie Pierre J., Targeting integrins to promote bone formation and repair, Nature Reviews Endocrinology, 9, 5, 2013. Crossref
-
Chung Rosa, Foster Bruce K., Xian Cory J., Inhibition of protein kinase-D promotes cartilage repair at injured growth plate in rats, Injury, 44, 7, 2013. Crossref
-
Gay I., Cavender A., Peto D., Sun Z., Speer A., Cao H., Amendt B. A., Differentiation of human dental stem cells reveals a role for microRNA-218, Journal of Periodontal Research, 49, 1, 2014. Crossref
-
Helth A., Gostin P.F., Oswald S., Wendrock H., Wolff U., Hempel U., Arnhold S., Calin M., Eckert J., Gebert A., Chemical nanoroughening of Ti40Nb surfaces and its effect on human mesenchymal stromal cell response, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 102, 1, 2014. Crossref
-
Sévère N, Dieudonné F-X, Marie P J, E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis, Cell Death & Disease, 4, 1, 2013. Crossref
-
Kang Kyung Shin, Hong Jung Min, Kang Jo A, Rhie Jong-Won, Jeong Young Hun, Cho Dong-Woo, Regulation of osteogenic differentiation of human adipose-derived stem cells by controlling electromagnetic field conditions, Experimental & Molecular Medicine, 45, 1, 2013. Crossref
-
Adhami Mitra D, Rashid Harunur, Chen Haiyan, Clarke John C, Yang Yang, Javed Amjad, Loss of Runx2 in Committed Osteoblasts Impairs Postnatal Skeletogenesis, Journal of Bone and Mineral Research, 30, 1, 2015. Crossref
-
Beederman Maureen, Farina Evan M., Reid Russell R., Molecular basis of cranial suture biology and disease: Osteoblastic and osteoclastic perspectives, Genes & Diseases, 1, 1, 2014. Crossref
-
Chen Haiyan, Ghori-Javed Farah Y, Rashid Harunur, Adhami Mitra D, Serra Rosa, Gutierrez Soraya E, Javed Amjad, Runx2 Regulates Endochondral Ossification Through Control of Chondrocyte Proliferation and Differentiation, Journal of Bone and Mineral Research, 29, 12, 2014. Crossref
-
Fu Jia-Hui, Rios Hector, Al-Hezaimi Khalid, Oh Tae-Ju, Benavides Erika, Wang Hom-Lay, A randomized clinical trial evaluating the efficacy of the sandwich bone augmentation technique in increasing buccal bone thickness during implant placement. II. Tomographic, histologic, immunohistochemical, and RNA analyses, Clinical Oral Implants Research, 26, 10, 2015. Crossref
-
Tai Phillip W.L., Wu Hai, Gordon Jonathan A.R., Whitfield Troy W., Barutcu A. Rasim, van Wijnen André J., Lian Jane B., Stein Gary S., Stein Janet L., Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region, Gene, 550, 1, 2014. Crossref
-
Bagheri Zahra S., Giles Erica, El Sawi Ihab, Amleh Asma, Schemitsch Emil H., Zdero Radovan, Bougherara Habiba, Osteogenesis and cytotoxicity of a new Carbon Fiber/Flax/Epoxy composite material for bone fracture plate applications, Materials Science and Engineering: C, 46, 2015. Crossref
-
Li Yunpeng, Hou Rui, Wang Yibo, Lu Bin, Zhang Junrui, Feng Xinghua, Liu Yanpu, Cao Qiang, Fundamental study of application of umbilical cord mesenchymal stem cells to the periodontium to aid healing after autotransplantation of teeth, British Journal of Oral and Maxillofacial Surgery, 52, 6, 2014. Crossref
-
Noack Carolin, Hempel Ute, Preissler Carolin, Dieter Peter, Prostaglandin E2 impairs osteogenic and facilitates adipogenic differentiation of human bone marrow stromal cells, Prostaglandins, Leukotrienes and Essential Fatty Acids, 94, 2015. Crossref
-
Martin J. W., Zielenska M., Stein G. S., van Wijnen A. J., Squire J. A., The Role of RUNX2 in Osteosarcoma Oncogenesis, Sarcoma, 2011, 2011. Crossref
-
Rozas Moreno Pedro, Reyes García Rebeca, García Martín Antonia, Desarrollo normal del esqueleto y regulación de la formación y reabsorción óseas, in El hueso en las enfermedades endocrinas y nutricionales, 2014. Crossref
-
Barutcu A. Rasim, Tai Phillip W. L., Wu Hai, Gordon Jonathan A. R., Whitfield Troy W., Dobson Jason R., Imbalzano Anthony N., Lian Jane B., van Wijnen André J., Stein Janet L., Stein Gary S., The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter, Nucleic Acids Research, 42, 16, 2014. Crossref
-
Sciandra Marika, Marino Maria Teresa, Manara Maria Cristina, Guerzoni Clara, Grano Maria, Oranger Angela, Lucarelli Enrico, Lollini Pier‐Luigi, Dozza Barbara, Pratelli Loredana, Di Renzo Maria Flavia, Colombo Mario Paolo, Picci Piero, Scotlandi Katia, CD99 Drives Terminal Differentiation of Osteosarcoma Cells by Acting as a Spatial Regulator of ERK 1/2, Journal of Bone and Mineral Research, 29, 5, 2014. Crossref
-
Qiu Shang, Zhao Fengchao, Tang Xianye, Pei Fang, Dong Hongyan, Zhu Liang, Guo Kaijin, Type-2 cannabinoid receptor regulates proliferation, apoptosis, differentiation, and OPG/RANKL ratio of MC3T3-E1 cells exposed to Titanium particles, Molecular and Cellular Biochemistry, 399, 1-2, 2015. Crossref
-
Tan Shuang, Zhang Binbin, Zhu Xiaomei, Ao Ping, Guo Huajie, Yi Weihong, Zhou Guang-Qian, Deregulation of Bone Forming Cells in Bone Diseases and Anabolic Effects of Strontium-Containing Agents and Biomaterials, BioMed Research International, 2014, 2014. Crossref
-
Robaszkiewicz Agnieszka, Valkó Zsuzsanna, Kovács Katalin, Hegedűs Csaba, Bakondi Edina, Bai Péter, Virág László, The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway, Free Radical Biology and Medicine, 76, 2014. Crossref
-
Tai Phillip W.L., Zaidi Sayyed K., Wu Hai, Grandy Rodrigo A., Montecino Martin, van Wijnen André J., Lian Jane B., Stein Gary S., Stein Janet L., The Dynamic Architectural and Epigenetic Nuclear Landscape: Developing the Genomic Almanac of Biology and Disease, Journal of Cellular Physiology, 229, 6, 2014. Crossref
-
Przybylowski Colin, Ammar Mohamed, LeBlon Courtney, Jedlicka Sabrina S., Osteogenesis of MC3T3 Preosteoblasts on 3D Bioactive Peptide Modified Nano-Macroporous Bioactive Glass Scaffolds, Journal of Biomaterials and Nanobiotechnology, 06, 03, 2015. Crossref
-
Martin Jeff W., Squire Jeremy A., Zielenska Maria, The Genetics of Osteosarcoma, Sarcoma, 2012, 2012. Crossref
-
Nabiyouni Maryam, Ren Yufu, Bhaduri Sarit B., Magnesium substitution in the structure of orthopedic nanoparticles: A comparison between amorphous magnesium phosphates, calcium magnesium phosphates, and hydroxyapatites, Materials Science and Engineering: C, 52, 2015. Crossref
-
Yao Qingzhou, Song Rui, Ao Lihua, Zhan Qiong, Cleveland Joseph C., Yu Xiyong, Fullerton David A., Meng Xianzhong, Over-expression of neurotrophin 3 in human aortic valves affected by calcific disease induces the osteogenic responses via the Trk–Akt pathway, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852, 9, 2015. Crossref
-
Tonetto André, Lago Pablo Walker, Borba Márcia, Rosa Vinícius, Effects of chrondro-osseous regenerative compound associated with local treatments in the regeneration of bone defects around implants: an in vivo study, Clinical Oral Investigations, 20, 2, 2016. Crossref
-
Hwang Pai-An, Hung Yu-Lan, Phan Nam Nhut, Hieu Bui-Thi-Ngoc, Chang Po-Ming, Li Kuan-Lun, Lin Yen-Chang, The in vitro and in vivo effects of the low molecular weight fucoidan on the bone osteogenic differentiation properties, Cytotechnology, 68, 4, 2016. Crossref
-
Al Mamun Md. Abdullah, Hosen Mohammad Jakir, Islam Kamrul, Khatun Amina, Alam M. Masihul, Al-Bari Md. Abdul Alim, Tridax procumbens flavonoids promote osteoblast differentiation and bone formation, Biological Research, 48, 1, 2015. Crossref
-
Park Sarah S., Beyer Richard P., Smyth Matthew D., Clarke Christine M., Timms Andrew E., Bammler Theo K., Stamper Brendan D., Mecham Brigham H., Gustafson Jennifer A., Cunningham Michael L., Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis, Bone, 76, 2015. Crossref
-
Qiao Shi-Chong, Du Juan, Zhao Jing-Mei, Shi Jun-Yu, Gu Ying-Xin, Lai Hong-Chang, Effects of a Hydroxyapatite-Coated Nanotube Surface of Titanium on MC3T3-E1 Cells, Implant Dentistry, Publish Ahead of, 2015. Crossref
-
AUBIN JANE E., HEERSCHE JOHAN N.M., Vitamin D and Osteoblasts, in Vitamin D, 2005. Crossref
-
Oranger Angela, Brunetti Giacomina, Carbone Claudia, Colaianni Graziana, Mongelli Teresa, Gigante Isabella, Tamma Roberto, Mori Giorgio, Di Benedetto Adriana, Sciandra Marika, Ventura Selena, Scotlandi Katia, Colucci Silvia, Grano Maria, Human Myeloma Cell Lines Induce Osteoblast Downregulation of CD99 Which Is Involved in Osteoblast Formation and Activity, Journal of Immunology Research, 2015, 2015. Crossref
-
Belavý Daniel L., Baecker Natalie, Armbrecht Gabriele, Beller Gisela, Buehlmeier Judith, Frings-Meuthen Petra, Rittweger Jörn, Roth Heinz J., Heer Martina, Felsenberg Dieter, Serum sclerostin and DKK1 in relation to exercise against bone loss in experimental bed rest, Journal of Bone and Mineral Metabolism, 34, 3, 2016. Crossref
-
LIAN JANE B., STEIN GARY S., Osteoblast Biology, in Osteoporosis, 2008. Crossref
-
Li Ming, Wu Wei, Tan Lei, Mu Degong, Zhu Dong, Wang Jian, Zhao Bin, Low-magnitude mechanical vibration regulates expression of osteogenic proteins in ovariectomized rats, Biochemical and Biophysical Research Communications, 465, 3, 2015. Crossref
-
Mori Giorgio, D'Amelio Patrizia, Faccio Roberta, Brunetti Giacomina, The Interplay between the Bone and the Immune System, Clinical and Developmental Immunology, 2013, 2013. Crossref
-
Kim Se-Young, Kim Yeon-Ji, An Young Jae, Lee Hae-Jeung, Lee Sung-Hyen, Kim Jung-Bong, Kim Haeng-Ran, Lee Sung-Joon, Black Rice (Oryza Sativa, Heukmi) Extracts Stimulate Osteogenesis but Inhibit Adipogenesis in Mesenchymal C3H10T1/2 Cells, Journal of Food Biochemistry, 40, 2, 2016. Crossref
-
Friedl G., Schmidt H., Rehak I., Kostner G., Schauenstein K., Windhager R., Undifferentiated human mesenchymal stem cells (hMSCs) are highly sensitive to mechanical strain: transcriptionally controlled early osteo-chondrogenic response in vitro, Osteoarthritis and Cartilage, 15, 11, 2007. Crossref
-
Vimalraj S., Arumugam B., Miranda P.J., Selvamurugan N., Runx2: Structure, function, and phosphorylation in osteoblast differentiation, International Journal of Biological Macromolecules, 78, 2015. Crossref
-
Fang Sijie, Deng Yuan, Gu Ping, Fan Xianqun, MicroRNAs Regulate Bone Development and Regeneration, International Journal of Molecular Sciences, 16, 12, 2015. Crossref
-
Pagni Giorgio, Stem Cells for Periodontal Regeneration, in Dental Stem Cells: Regenerative Potential, 2016. Crossref
-
Serrano-Candelas Eva, Farré Domènec, Aranguren-Ibáñez Álvaro, Martínez-Høyer Sergio, Pérez-Riba Mercè, Callaerts Patrick, The Vertebrate RCAN Gene Family: Novel Insights into Evolution, Structure and Regulation, PLoS ONE, 9, 1, 2014. Crossref
-
Jin Sung-Ki, Lee Joo-Heon, Hong Joo-Hee, Park Jung-Keug, Seo Young-Kwon, Kwon Soon-Yong, Enhancement of osseointegration of artificial ligament by nano-hydroxyapatite and bone morphogenic protein-2 into the rabbit femur, Tissue Engineering and Regenerative Medicine, 13, 3, 2016. Crossref
-
Suttamanatwong Supaporn, MicroRNAs in bone development and their diagnostic and therapeutic potentials in osteoporosis, Connective Tissue Research, 58, 1, 2017. Crossref
-
Bhat Ramray, Pally Dharma, Ontogeny, Oncogeny and Phylogeny: Deep Associations, in Evolutionary Biology, 2016. Crossref
-
Choudhary Dharmendra, Kushwaha Priyanka, Gautam Jyoti, Kumar Padam, Verma Ashwani, Kumar Avinash, Maurya Saransh Wales, Siddiqui Ibadur Rahman, Mishra Prabhat Ranjan, Maurya Rakesh, Trivedi Ritu, Fast and long acting neoflavonoids dalbergin isolated from Dalbergia sissoo heartwood is osteoprotective in ovariectomized model of osteoporosis: Osteoprotective effect of Dalbergin, Biomedicine & Pharmacotherapy, 83, 2016. Crossref
-
Wang Na, Sui Fang, Ma Jingjing, Su Xi, Liu Jiazhe, Yao Demao, Shi Bingyin, Hou Peng, Yang Qi, Site-specific Hypermethylation of RUNX3 Predicts Poor Prognosis in Gastric Cancer, Archives of Medical Research, 47, 4, 2016. Crossref
-
Martinez Milka, Hinojosa Marcela, Trombly Daniel, Morin Violeta, Stein Janet, Stein Gary, Javed Amjad, Gutierrez Soraya E., van Wijnen Andre, Transcriptional Auto-Regulation of RUNX1 P1 Promoter, PLOS ONE, 11, 2, 2016. Crossref
-
Qian Shaomin, Regan Jenna N., Shelton Maxwell T., Hoggatt April, Mohammad Khalid S., Herring Paul B., Seye Cheikh I., The P2Y 2 nucleotide receptor is an inhibitor of vascular calcification, Atherosclerosis, 257, 2017. Crossref
-
Twine Natalie A., Harkness Linda, Kassem Moustapha, Wilkins Marc R., Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells, BMC Genomics, 17, 1, 2016. Crossref
-
Hawse John R., Cicek Muzaffer, Grygo Sarah B., Bruinsma Elizabeth S., Rajamannan Nalini M., van Wijnen Andre J., Lian Jane B., Stein Gary S., Oursler Merry Jo, Subramaniam Malayannan, Spelsberg Thomas C., Polymenis Michael, TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts, PLoS ONE, 6, 4, 2011. Crossref
-
Qiao Xiaoyong, Nie Ying, Ma Yaxian, Chen Yan, Cheng Ran, Yin Weiyao, Hu Ying, Xu Wenming, Xu Liangzhi, Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways, Scientific Reports, 6, 1, 2016. Crossref
-
HUANG JIANG, LIU LIMING, FENG MINGLI, AN SHUAI, ZHOU MENG, LI ZHENG, QI JIAJIAN, SHEN HUILIANG, Effect of CoCl2 on fracture repair in a rat model of bone fracture, Molecular Medicine Reports, 12, 4, 2015. Crossref
-
Bennis Y., Wolber A., Vinchon M., Belkhou A., Duquennoy-Martinot V., Guerreschi P., Les craniosténoses non syndromiques, Annales de Chirurgie Plastique Esthétique, 61, 5, 2016. Crossref
-
Hempel Ute, Müller Katrin, Preissler Carolin, Noack Carolin, Boxberger Sabine, Dieter Peter, Bornhäuser Martin, Wobus Manja, Human Bone Marrow Stromal Cells: A Reliable, Challenging Tool forIn VitroOsteogenesis and Bone Tissue Engineering Approaches, Stem Cells International, 2016, 2016. Crossref
-
Shakibaei Mehdi, Shayan Parviz, Busch Franziska, Aldinger Constance, Buhrmann Constanze, Lueders Cora, Mobasheri Ali, Vanacker Jean-Marc, Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation, PLoS ONE, 7, 4, 2012. Crossref
-
Zhai Mingming, Jing Da, Tong Shichao, Wu Yan, Wang Pan, Zeng Zhaobin, Shen Guanghao, Wang Xin, Xu Qiaoling, Luo Erping, Pulsed electromagnetic fields promote in vitro osteoblastogenesis through a Wnt/β-catenin signaling-associated mechanism, Bioelectromagnetics, 37, 3, 2016. Crossref
-
Leem Jaechan, Lee In-Kyu, Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4, Endocrinology and Metabolism, 31, 1, 2016. Crossref
-
Yang Wen Wei, Guo Bin, Jia Wen Yuan, Jia Yue, Porphyromonas gingivalis-derived outer membrane vesicles promote calcification of vascular smooth muscle cells through ERK1/2-RUNX2, FEBS Open Bio, 6, 12, 2016. Crossref
-
Monti Manuela, Graziano Antonio, Rizzo Silvana, Perotti Cesare, Del Fante Claudia, d'Aquino Riccardo, Redi Carlo Alberto, Rodriguez y Baena Ruggero, In Vitro and In Vivo Differentiation of Progenitor Stem Cells Obtained After Mechanical Digestion of Human Dental Pulp, Journal of Cellular Physiology, 232, 3, 2017. Crossref
-
Kong Xianghe, Wang Fang, Niu Yinbo, Wu Xianglong, Pan Yalei, A comparative study on the effect of promoting the osteogenic function of osteoblasts using isoflavones from Radix Astragalus, Phytotherapy Research, 32, 1, 2018. Crossref
-
Javed Amjad, Bae Jong-Sup, Afzal Faiza, Gutierrez Soraya, Pratap Jitesh, Zaidi Sayyed K., Lou Yang, van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal, Journal of Biological Chemistry, 283, 13, 2008. Crossref
-
LI JIA, HAO LINGYU, WU JUNHUA, ZHANG JIQUAN, SU JIANSHENG, Linarin promotes osteogenic differentiation by activating the BMP-2/RUNX2 pathway via protein kinase A signaling, International Journal of Molecular Medicine, 37, 4, 2016. Crossref
-
Leong David T, Lim Joleen, Goh Xuewei, Pratap Jitesh, Pereira Barry P, Kwok Hui Si, Nathan Saminathan Suresh, Dobson Jason R, Lian Jane B, Ito Yoshiaki, Voorhoeve P Mathijs, Stein Gary S, Salto-Tellez Manuel, Cool Simon M, van Wijnen Andre J, Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility, Breast Cancer Research, 12, 5, 2010. Crossref
-
Bhattarai G., Lee Y.H., Lee M.H., Yi H.K., Gene Delivery of c-myb Increases Bone Formation Surrounding Oral Implants, Journal of Dental Research, 92, 9, 2013. Crossref
-
Smolle Maria A., Haybaeck Johannes, Molecular Pathogenesis of Bone Tumours, in Mechanisms of Molecular Carcinogenesis – Volume 2, 2017. Crossref
-
Spieker Janine, Mudersbach Thomas, Vogel-Höpker Astrid, Layer Paul G., Silman Israel, Endochondral Ossification Is Accelerated in Cholinesterase-Deficient Mice and in Avian Mesenchymal Micromass Cultures, PLOS ONE, 12, 1, 2017. Crossref
-
Bord Sharyn, Ireland Deborah C., Moffatt Pierre, Thomas Gethin P., Compston Juliet E., Characterization of Osteocrin Expression in Human Bone, Journal of Histochemistry & Cytochemistry, 53, 10, 2005. Crossref
-
Blecher Ronen, Krief Sharon, Galili Tal, Assaraf Eran, Stern Tomer, Anekstein Yoram, Agar Gabriel, Zelzer Elazar, The Proprioceptive System Regulates Morphologic Restoration of Fractured Bones, Cell Reports, 20, 8, 2017. Crossref
-
Handschin Alexander E., Egermann Marcus, Trentz Otmar, Wanner Guido A., Kock Hans-Jürgen, Zünd Gregor, Trentz Omana Anna, Cbfa-1 (Runx-2) and Osteocalcin Expression by Human Osteoblasts in Heparin Osteoporosis in Vitro, Clinical and Applied Thrombosis/Hemostasis, 12, 4, 2006. Crossref
-
Peng Wei, Zhu Shuang-Xi, Wang Jin, Chen Li-Li, Weng Jun-Quan, Chen Song-Ling, Lnc-NTF3-5 promotes osteogenic differentiation of maxillary sinus membrane stem cells via sponging miR-93-3p, Clinical Implant Dentistry and Related Research, 20, 2, 2018. Crossref
-
Zhou Meng, Lu Shibao, Lu Guowei, Huang Jiang, Liu Limin, An Shuai, Li Zheng, Shen Huiliang, Effects of remote ischemic post-conditioning on fracture healing in rats, Molecular Medicine Reports, 15, 5, 2017. Crossref
-
Li Fei, Yao Qingzhou, Ao Lihua, Cleveland Joseph C., Dong Nianguo, Fullerton David A., Meng Xianzhong, Klotho suppresses high phosphate-induced osteogenic responses in human aortic valve interstitial cells through inhibition of Sox9, Journal of Molecular Medicine, 95, 7, 2017. Crossref
-
MacFarlane Elena Gallo, Haupt Julia, Dietz Harry C., Shore Eileen M., TGF-β Family Signaling in Connective Tissue and Skeletal Diseases, Cold Spring Harbor Perspectives in Biology, 9, 11, 2017. Crossref
-
Gilbert Linda C., Rubin Janet, Nanes Mark S., The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis, American Journal of Physiology-Endocrinology and Metabolism, 288, 5, 2005. Crossref
-
Ono Minagi Hitomi, Sarper Safiye Esra, Kurosaka Hiroshi, Kuremoto Koh-ichi, Taniuchi Ichiro, Sakai Takayoshi, Yamashiro Takashi, Fraidenraich Diego, Runx1 mediates the development of the granular convoluted tubules in the submandibular glands, PLOS ONE, 12, 9, 2017. Crossref
-
Dernowsek Janaína A., Pereira Milena C., Fornari Thaís A., Macedo Claudia, Assis Amanda F., Donate Paula B., Bombonato‐Prado Karina F., Passos‐Bueno Maria Rita, Passos Geraldo A., Posttranscriptional Interaction Between miR‐450a‐5p and miR‐28‐5p and STAT1 mRNA Triggers Osteoblastic Differentiation of Human Mesenchymal Stem Cells, Journal of Cellular Biochemistry, 118, 11, 2017. Crossref
-
Kaptan Engin, Sancar Bas Serap, Sancakli Aylin, Aktas Hatice Gumushan, Bayrak Bertan Boran, Yanardag Refiye, Bolkent Sehnaz, Runt‐Related Transcription Factor 2 (Runx2) Is Responsible for Galectin‐3 Overexpression in Human Thyroid Carcinoma, Journal of Cellular Biochemistry, 118, 11, 2017. Crossref
-
Hosoya Akihiro, Yukita Akira, Yoshiba Kunihiko, Yoshiba Nagako, Takahashi Masafumi, Nakamura Hiroaki, Two Distinct Processes of Bone-like Tissue Formation by Dental Pulp Cells after Tooth Transplantation, Journal of Histochemistry & Cytochemistry, 60, 11, 2012. Crossref
-
Byon Chang Hyun, Javed Amjad, Dai Qun, Kappes John C., Clemens Thomas L., Darley-Usmar Victor M., McDonald Jay M., Chen Yabing, Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling, Journal of Biological Chemistry, 283, 22, 2008. Crossref
-
Kawarizadeh A., Bourauel C., Götz W., Jäger A., Early Responses of Periodontal Ligament Cells to Mechanical Stimulus in vivo, Journal of Dental Research, 84, 10, 2005. Crossref
-
Oster Michael, Just Franziska, Büsing Kirsten, Wolf Petra, Polley Christian, Vollmar Brigitte, Muráni Eduard, Ponsuksili Siriluck, Wimmers Klaus, Toward improved phosphorus efficiency in monogastrics—interplay of serum, minerals, bone, and immune system after divergent dietary phosphorus supply in swine, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 310, 10, 2016. Crossref
-
Ge Chunxi, Xiao Guozhi, Jiang Di, Yang Qian, Hatch Nan E., Roca Hernan, Franceschi Renny T., Identification and Functional Characterization of ERK/MAPK Phosphorylation Sites in the Runx2 Transcription Factor, Journal of Biological Chemistry, 284, 47, 2009. Crossref
-
Zhang C.Y., Zheng S.G., Wang Y.X., Zhu J.X., Zhu X., Zhao Y.M., Ge L.H., Novel RUNX2 Mutations in Chinese Individuals with Cleidocranial Dysplasia, Journal of Dental Research, 88, 9, 2009. Crossref
-
Hosoya Akihiro, Nakamura Hiroaki, Ninomiya Tadashi, Yoshiba Kunihiko, Yoshiba Nagako, Nakaya Hiroyuki, Wakitani Shigeyuki, Yamada Hirohito, Kasahara Etsuo, Ozawa Hidehiro, Immunohistochemical Localization of α-Smooth Muscle Actin During Rat Molar Tooth Development, Journal of Histochemistry & Cytochemistry, 54, 12, 2006. Crossref
-
Lee Kyoung-Mi, Park Kwang Hwan, Hwang Ji Suk, Lee Moses, Yoon Dong Suk, Ryu Hyun Aae, Jung Ho Sun, Park Ki Won, Kim Jihyun, Park Sahng Wook, Kim Sung-Hwan, Chun Yong-Min, Choi Woo Jin, Lee Jin Woo, Inhibition of STAT5A promotes osteogenesis by DLX5 regulation, Cell Death & Disease, 9, 11, 2018. Crossref
-
Li Xing, Chang Bei, Wang Banchao, Bu Wenhuan, Zhao Liang, Liu Jie, Meng Lin, Wang Lu, Xin Ying, Wang Dandan, Tang Qi, Zheng Changyu, Sun Hongchen, Rapamycin promotes osteogenesis under inflammatory conditions, Molecular Medicine Reports, 16, 6, 2017. Crossref
-
Petrella Ross A, Mollica Peter A, Zamponi Martina, Reid John A, Xiao Shu, Bruno Robert D, Sachs Patrick C, 3D bioprinter applied picosecond pulsed electric fields for targeted manipulation of proliferation and lineage specific gene expression in neural stem cells, Journal of Neural Engineering, 15, 5, 2018. Crossref
-
Brunetti Giacomina, Colaianni Graziana, Colucci Silvia, Grano Maria, Anatomy and Physiology of Skeletal Tissue: The Bone Cells, in Multidisciplinary Approach to Osteoporosis, 2018. Crossref
-
Ko Dongwoo, Lim Jeong Mook, Biology and Potential Use of Chicken Bone Marrow-derived Cells, Journal of Animal Reproduction and Biotechnology, 33, 1, 2018. Crossref
-
Rajshankar Dhaarmini, Wang Yongqiang, McCulloch Christopher A., Osteogenesis requires FAK‐dependent collagen synthesis by fibroblasts and osteoblasts, The FASEB Journal, 31, 3, 2017. Crossref
-
Shen Sibo, Cai Shu, Bao Xiaogang, Xu Peng, Li Yue, Jiang Song, Xu Guohua, Biomimetic fluoridated hydroxyapatite coating with micron/nano-topography on magnesium alloy for orthopaedic application, Chemical Engineering Journal, 339, 2018. Crossref
-
Hamidouche Zahia, Haÿ Eric, Vaudin Pascal, Charbord Pierre, Schüle Roland, Marie Pierre J., Fromigué Olivia, FHL2 mediates dexamethasone‐induced mesenchymal cell differentiation into osteoblasts by activating Wnt/β‐catenin signaling‐dependent Runx2 expression, The FASEB Journal, 22, 11, 2008. Crossref
-
Kim Ji-Eun, Takanche Jyoti Shrestha, Kim Jeong-Seok, Lee Min-Ho, Jeon Jae-Gyu, Park Il-Song, Yi Ho-Keun, Phelligridin D-loaded oral nanotube titanium implant enhances osseointegration and prevents osteolysis in rat mandible, Artificial Cells, Nanomedicine, and Biotechnology, 46, sup2, 2018. Crossref
-
Weiyang Su, Chienwei Feng, Chungchih Tseng, Hanchun Hung, Zhicheng Chen, Hsinpai Lee, Yenhsuan Jean, Sean Wu Shingyi, Zhihong Wen, Therapeutic effect of Guijiajiao (Colla Carapacis et Plastri) on bone regeneration in rats and zebrafish, Journal of Traditional Chinese Medicine, 38, 2, 2018. Crossref
-
Klees Robert F., Salasznyk Roman M., Kingsley Karl, Williams William A., Boskey Adele, Plopper George E., Laminin-5 Induces Osteogenic Gene Expression in Human Mesenchymal Stem Cells through an ERK-dependent Pathway, Molecular Biology of the Cell, 16, 2, 2005. Crossref
-
Manara Maria Cristina, Bernard Ghislaine, Lollini Pier-Luigi, Nanni Patrizia, Zuntini Monia, Landuzzi Lorena, Benini Stefania, Lattanzi Giovanna, Sciandra Marika, Serra Massimo, Colombo Mario Paolo, Bernard Alain, Picci Piero, Scotlandi Katia, CD99 Acts as an Oncosuppressor in Osteosarcoma, Molecular Biology of the Cell, 17, 4, 2006. Crossref
-
Wang Yi, Shi Zhi Yun, Feng Jin, Cao Jun Kai, HDAC6 regulates dental mesenchymal stem cells and osteoclast differentiation, BMC Oral Health, 18, 1, 2018. Crossref
-
Pasello Michela, Manara Maria Cristina, Scotlandi Katia, CD99 at the crossroads of physiology and pathology, Journal of Cell Communication and Signaling, 12, 1, 2018. Crossref
-
Malek Natalia, Starowicz Katarzyna, Joint problems arising from lack of repair mechanisms: can cannabinoids help?, British Journal of Pharmacology, 176, 10, 2019. Crossref
-
Nirmala Farida Sukma, Lee Hyunjung, Kim Ji‐Sun, Jung Chang Hwa, Ha Tae‐Youl, Jang Young Jin, Ahn Jiyun, Fermentation Improves the Preventive Effect of Soybean Against Bone Loss in Senescence‐Accelerated Mouse Prone 6, Journal of Food Science, 84, 2, 2019. Crossref
-
Saiganesh S., Saathvika R., Arumugam B., Vishal M., Udhaya V., Ilangovan R., Selvamurugan N., TGF-β1-stimulation of matrix metalloproteinase-13 expression by down-regulation of miR-203a-5p in rat osteoblasts, International Journal of Biological Macromolecules, 132, 2019. Crossref
-
Oranger Angela, Colaianni Graziana, Grano Maria, Bone Cells, in Imaging of Prosthetic Joints, 2014. Crossref
-
Lin Weiping, Xu Liangliang, Pan Qi, Lin Sien, Feng Lu, Wang Bin, Chen Shuxun, Li Ying, Wang Haixing, Li Yucong, Wang Yan, Lee Wayne Yuk Wai, Sun Dong, Li Gang, Lgr5‐overexpressing mesenchymal stem cells augment fracture healing through regulation of Wnt/ERK signaling pathways and mitochondrial dynamics, The FASEB Journal, 33, 7, 2019. Crossref
-
Shao Pei-Lin, Wu Shun-Cheng, Lin Zih-Yin, Ho Mei-Ling, Chen Chung-Hwan, Wang Chau-Zen, Alpha-5 Integrin Mediates Simvastatin-Induced Osteogenesis of Bone Marrow Mesenchymal Stem Cells, International Journal of Molecular Sciences, 20, 3, 2019. Crossref
-
Long Haitao, Zhu Yong, Lin Zhangyuan, Wan Jun, Cheng Liang, Zeng Min, Tang Yifu, Zhao Ruibo, miR-381 modulates human bone mesenchymal stromal cells (BMSCs) osteogenesis via suppressing Wnt signaling pathway during atrophic nonunion development, Cell Death & Disease, 10, 7, 2019. Crossref
-
Fujimori Ko, Iguchi Yusuke, Yamashita Yukiko, Gohda Keigo, Teno Naoki, Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts, Molecules, 24, 22, 2019. Crossref
-
Rovai Emanuel Silva, Ambrósio Lucas Macedo Batitucci, de França Bruno Nunes, de Oliveira Letícia Rodrigues, Gasparoni Letícia Miquelitto, Sipert Carla Renata, Holzhausen Marinella, Protease-Activated Receptor Type 1 Activation Enhances Osteogenic Activity in Human Periodontal Ligament Stem Cells, Stem Cells International, 2019, 2019. Crossref
-
Acartürk T. Oğuz, Adipose Tissue Engineering, in Fundamentals of Tissue Engineering and Regenerative Medicine, 2009. Crossref
-
Raut Nishikant, Wicks Sheila M., Lawal Tempitope O., Mahady Gail B., Epigenetic regulation of bone remodeling by natural compounds, Pharmacological Research, 147, 2019. Crossref
-
Oren Moshe, Aylon Yael, Introduction, in The Hippo Signaling Pathway and Cancer, 2013. Crossref
-
Li Yixuan, Zhang Wei, Ren Fazheng, Guo Huiyuan, Activation of TGF-β Canonical and Noncanonical Signaling in Bovine Lactoferrin-Induced Osteogenic Activity of C3H10T1/2 Mesenchymal Stem Cells, International Journal of Molecular Sciences, 20, 12, 2019. Crossref
-
Wu Wenmin, He Lichao, Li Chengliang, Zhao Shilin, Liang Yanhui, Yang Fang, Zhang Min, Jin Guofeng, Ma Meihu, Phosphorylation of porcine bone collagen peptide to improve its calcium chelating capacity and its effect on promoting the proliferation, differentiation and mineralization of osteoblastic MC3T3-E1 cells, Journal of Functional Foods, 64, 2020. Crossref
-
Chambers Phil, McCarthy Helen O., Dunne Nicholas J., Emerging areas of bone repair materials, in Bone Repair Biomaterials, 2019. Crossref
-
Wang Jingyu, Du Lele, Fu Yingmei, Jiang Peidong, Wang Xiumei, ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum, BMC Oral Health, 19, 1, 2019. Crossref
-
Bab Itai A., The skeleton: stone bones and stoned heads?, in Cannabinoids as Therapeutics, 2005. Crossref
-
Montecino Martin A., Lian Jane B., Stein Janet L., Stein Gary S., van Wijnen André J., Cruzat Fernando, Biological and Molecular Effects of Vitamin D on Bone, in Vitamin D, 2010. Crossref
-
Kim Mihyang, Kang Jeong Hyeon, Oh Geun Hye, Park Mi Hwa, Ishige sinicola extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway, Zeitschrift für Naturforschung C, 74, 7-8, 2019. Crossref
-
MacDougall Mary J., Javed Amjad, Dentin and Bone: Similar Collagenous Mineralized Tissues, in Bone and Development, 2010. Crossref
-
Lin Chien-Chou, Chang Walter Hong-Shong, Cheng Tsai-Mu, Chiu Li-Hsuan, Wang Yen-Hsun, Lin Cheng-An J., Ho Yuan-Soon, Zuo Chun S., Wang Yun-Ming, Lai Wen-Fu Thomas, Two new, near-infrared, fluorescent probes as potential tools for imaging bone repair, Scientific Reports, 10, 1, 2020. Crossref
-
Shalehin Nazmus, Hosoya Akihiro, Takebe Hiroaki, Hasan Md Riasat, Irie Kazuharu, Boric acid inhibits alveolar bone loss in rat experimental periodontitis through diminished bone resorption and enhanced osteoblast formation, Journal of Dental Sciences, 15, 4, 2020. Crossref
-
Cheng Cheng-I, Chang Huoy-Rou, Tai Ming-Hong, Chou Ming-Huei, Chen Guan-Ting, Chen Po-Han, Kao Ying-Hsien, Hepatoma-derived growth factor enhances osteoblastic transformation of rat aortic vascular smooth muscle cells in vitro, Life Sciences, 256, 2020. Crossref
-
Xie Hui, Liu Ming, Jin Yaofeng, Lin Haiqing, Zhang Yushan, Zheng Song, miR-1323 suppresses bone mesenchymal stromal cell osteogenesis and fracture healing via inhibiting BMP4/SMAD4 signaling, Journal of Orthopaedic Surgery and Research, 15, 1, 2020. Crossref
-
Lin Yi-Tzu, Mao Yi-Wen, Imtiyaz Zuha, Chiou Wen-Fei, Lee Mei-Hsien, Comprehensive LC-MS/MS-based phytochemical perspectives and osteogenic effects of Uraria crinita, Food & Function, 11, 6, 2020. Crossref
-
Pavel Emilia, Nadella Kiran, Towns William H., Lawrence S. Lawrence S., Mutation of Prkar1a Causes Osteoblast Neoplasia Driven by Dysregulation of Protein Kinase A, Molecular Endocrinology, 22, 2, 2008. Crossref
-
Al‐Bari Abdul Alim, Al Mamun Abdullah, Current advances in regulation of bone homeostasis, FASEB BioAdvances, 2, 11, 2020. Crossref
-
Wang Wei-Hua, Wang Fei, Zhao Hai-Feng, Yan Ke, Huang Cui-Ling, Yin Yin, Huang Qiang, Chen Zao-Zao, Zhu Wen-Yu, Injectable Magnesium-Zinc Alloy Containing Hydrogel Complex for Bone Regeneration, Frontiers in Bioengineering and Biotechnology, 8, 2020. Crossref
-
Botolin Sergiu, McCabe Laura R., Bone Loss and Increased Bone Adiposity in Spontaneous and Pharmacologically Induced Diabetic Mice, Endocrinology, 148, 1, 2007. Crossref
-
Hewitt Jocelyn, Lu Xiaghuai, Gilbert Linda, Nanes Mark S., The Muscle Transcription Factor MyoD Promotes Osteoblast Differentiation by Stimulation of the Osterix Promoter, Endocrinology, 149, 7, 2008. Crossref
-
Li Donglan, Sinha Kislay K., Hay Maher A., Rinaldi Ciro R., Saunthararajah Yogen, Nucifora Giuseppina, RUNX1-RUNX1 Homodimerization Modulates RUNX1 Activity and Function, Journal of Biological Chemistry, 282, 18, 2007. Crossref
-
Saruta Juri, Ozawa Ryotaro, Hamajima Kosuke, Saita Makiko, Sato Nobuaki, Ishijima Manabu, Kitajima Hiroaki, Ogawa Takahiro, Prolonged Post-Polymerization Biocompatibility of Polymethylmethacrylate-Tri-n-Butylborane (PMMA-TBB) Bone Cement, Materials, 14, 5, 2021. Crossref
-
Yurova K. A., Melashchenko E. S., Khasiakhmatova O. G., Malashchenko V. V., Melashchenko O. B., Shunkin E. O., Norkin I. K., Khlusov I. A., Litvinova L. S., Mesenchymal stem cells: a brief review of classis concepts and new factors of osteogenic differentiation, Medical Immunology (Russia), 23, 2, 2021. Crossref
-
Al-Bari Md. Abdul Alim, Hossain Showna, Mia Ujjal, Al Mamun Md. Abdullah, Therapeutic and Mechanistic Approaches of Tridax Procumbens Flavonoids for the Treatment of Osteoporosis, Current Drug Targets, 21, 16, 2020. Crossref
-
Jafary Fariba, Vaezifar Sedigheh, Immobilization of Alkaline Phosphatase onto Chitosan Nanoparticles: a Novel Therapeutic Approach in Bone Tissue Engineering, BioNanoScience, 11, 4, 2021. Crossref
-
Marie Pierre J, Fromigué Olivia, Osteogenic differentiation of human marrow-derived mesenchymal stem cells, Regenerative Medicine, 1, 4, 2006. Crossref
-
Bandara Nadeeka, Gurusinghe Saliya, Lim Shiang Yong, Chen Haying, Chen Shuangfeng, Wang Dawei, Hilbert Bryan, Wang Le-Xin, Strappe Padraig, Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling, Stem Cell Research & Therapy, 7, 1, 2016. Crossref
-
Bornstein Bavat, Konstantin Nitzan, Alessandro Cristiano, Tresch Matthew C, Zelzer Elazar, More than movement: the proprioceptive system as a new regulator of musculoskeletal biology, Current Opinion in Physiology, 20, 2021. Crossref
-
Meyer Mark B., Benkusky Nancy A., Lee Chang-Hun, Pike J.Wesley, Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell Differentiation, Journal of Biological Chemistry, 289, 28, 2014. Crossref
-
Lian Jane B, Biology of bone mineralization, Current Opinion in Endocrinology and Diabetes, 13, 1, 2006. Crossref
-
Shur Irena, Solomon Ronit, Benayahu Dafna, Dynamic Interactions of Chromatin‐Related Mesenchymal Modulator, a Chromodomain Helicase‐DNA‐Binding Protein, with Promoters in Osteoprogenitors, STEM CELLS, 24, 5, 2006. Crossref
-
Ayariga Joseph A., Dean Morgan, Nyairo Elijah, Thomas Vinoy, Dean Derrick, PLA/HA Multiscale Nano-/Micro-Hybrid 3D Scaffolds Provide Inductive Cues to Stems Cells to Differentiate into an Osteogenic Lineage, JOM, 73, 12, 2021. Crossref
-
Zaragoza Carlos, López-Rivera Esther, García-Rama Concepción, Saura Marta, Martínez-Ruíz Antonio, Lizarbe Tania R., Martín-de-Lara Fernando, Lamas Santiago, Cbfa-1 mediates nitric oxide regulation of MMP-13 in osteoblasts, Journal of Cell Science, 119, 9, 2006. Crossref
-
Zaidi Sayyed K., Young Daniel W., Montecino Martin, van Wijnen Andre J., Stein Janet L., Lian Jane B., Stein Gary S., Bookmarking the Genome: Maintenance of Epigenetic Information, Journal of Biological Chemistry, 286, 21, 2011. Crossref
-
Hosen Mohammad J, Coucke Paul J, Le Saux Olivier, De Paepe Anne, Vanakker Olivier M, Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum, Orphanet Journal of Rare Diseases, 9, 1, 2014. Crossref
-
Choi Young-Ae, Lim Jiwon, Kim Kyung Min, Acharya Bodhraj, Cho Je-Yoel, Bae Yong-Chul, Shin Hong-In, Kim Shin-Yoon, Park Eui Kyun, Secretome Analysis of Human BMSCs and Identification of SMOC1 as an Important ECM Protein in Osteoblast Differentiation, Journal of Proteome Research, 9, 6, 2010. Crossref
-
Sadikovic Bekim, Thorner Paul, Chilton-MacNeill Susan, Martin Jeff W, Cervigne Nilva K, Squire Jeremy, Zielenska Maria, Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy, BMC Cancer, 10, 1, 2010. Crossref
-
Navid Fatemeh, Fischer Jeremy, Luo Yongquan, Colbert Robert A., Induced pluripotent stem cell–derived bone progenitors, in iPSC Derived Progenitors, 2022. Crossref
-
Ali Sayed A., Dobson Jason R., Lian Jane B., Stein Janet L., van Wijnen Andre J., Zaidi Sayyed K., Stein Gary S., A Runx2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation, Journal of Cell Science, 2012. Crossref
-
Hui Xin, Wang Mei, Zhang Lijun, Liu Ji, Wang Mengen, Hu Weiwei, Zhang Tongtong, Zhao Shijun, Geng Shangyong, Wang Xianjun, Zheng Zuncheng, Conditioned Media of Choroid Plexus Epithelium Cells Attenuates High Pi-Induced Calcification of MOVAS Cells by Inhibiting ROS-Mediated Signal Pathways, Frontiers in Physiology, 12, 2021. Crossref
-
Mechiche Alami Saad, Gangloff Sophie C., Laurent-Maquin Dominique, Wang Yun, Kerdjoudj Halima, Concise Review: In Vitro Formation of Bone-Like Nodules Sheds Light on the Application of Stem Cells for Bone Regeneration, Stem Cells Translational Medicine, 5, 11, 2016. Crossref
-
Lambertini Elisabetta, Penolazzi Letizia, Pellielo Giulia, Pipino Caterina, Pandolfi Assunta, Fiorito Serena, Epifano Francesco, Genovese Salvatore, Piva Roberta, Pro-Osteogenic Properties of Violina pumpkin (Cucurbita moschata) Leaf Extracts: Data from In Vitro Human Primary Cell Cultures, Nutrients, 13, 8, 2021. Crossref
-
Sullivan James C, Sher Daniel, Eisenstein Miriam, Shigesada Katsuya, Reitzel Adam M, Marlow Heather, Levanon Ditsa, Groner Yoram, Finnerty John R, Gat Uri, The evolutionary origin of the Runx/CBFbeta transcription factors – Studies of the most basal metazoans, BMC Evolutionary Biology, 8, 1, 2008. Crossref
-
Mitra Debika, Fatakdawala Hussain, Nguyen-Truong Michael, Creecy Amy, Nyman Jeffry, Marcu Laura, Leach J. Kent, Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy, ACS Biomaterials Science & Engineering, 3, 9, 2017. Crossref
-
Re Federica, Gabusi Elena, Manferdini Cristina, Russo Domenico, Lisignoli Gina, Bone Regeneration Improves with Mesenchymal Stem Cell Derived Extracellular Vesicles (EVs) Combined with Scaffolds: A Systematic Review, Biology, 10, 7, 2021. Crossref
-
Yang Seungchan, Quaresma Alexandre J. C., Nickerson Jeffrey A., Green Karin M., Shaffer Scott A., Imbalzano Anthony N., Martin-Buley Lori A., Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Subnuclear domain proteins in cancer cells support transcription factor RUNX2 functions in DNA damage response, Journal of Cell Science, 2015. Crossref
-
Hamidouche Zahia, Fromigué Olivia, Ringe Jochen, Häupl Thomas, Marie Pierre J, Crosstalks between integrin alpha 5 and IGF2/IGFBP2 signalling trigger human bone marrow-derived mesenchymal stromal osteogenic differentiation, BMC Cell Biology, 11, 1, 2010. Crossref
-
Huang Junchi, Hagberg Thulin Malin, Damber Jan-Erik, Welén Karin, The roles of RUNX2 and osteoclasts in regulating expression of steroidogenic enzymes in castration-resistant prostate cancer cells, Molecular and Cellular Endocrinology, 535, 2021. Crossref
-
Bakshi Rachit, Zaidi Sayyed K., Pande Sandhya, Hassan Mohammad Q., Young Daniel W., Montecino Martin, Lian Jane B., van Wijnen Andre J., Stein Janet L., Stein Gary S., The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes, Journal of Cell Science, 121, 23, 2008. Crossref
-
Owen Thomas A., Patel Chandni, Wei Shanqiao, Ho Chi S., Birmingham Kaylah, Sanchez Samuel, Chung Natalie, Cahill Alexa, O'Malley James P., Barrett Stephen D., Morano María Inés, KMN-159, a novel EP4 receptor selective agonist, stimulates osteoblastic differentiation in cultured whole rat bone marrow, Gene, 748, 2020. Crossref
-
Kyyak Solomiya, Blatt Sebastian, Schiegnitz Eik, Heimes Diana, Staedt Henning, Thiem Daniel G. E., Sagheb Keyvan, Al-Nawas Bilal, Kämmerer Peer W., Activation of Human Osteoblasts via Different Bovine Bone Substitute Materials With and Without Injectable Platelet Rich Fibrin in vitro, Frontiers in Bioengineering and Biotechnology, 9, 2021. Crossref
-
Kaabeche Karim, Guenou Hind, Bouvard Daniel, Didelot Nadège, Listrat Antoine, Marie Pierre J., Cbl-mediated ubiquitination of α5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation, Journal of Cell Science, 118, 6, 2005. Crossref
-
Spencer Virginia A., Costes Sylvain, Inman Jamie L., Xu Ren, Chen James, Hendzel Michael J., Bissell Mina J., Depletion of nuclear actin is a key mediator of quiescence in epithelial cells, Journal of Cell Science, 124, 1, 2011. Crossref
-
Gaur Tripti, Lengner Christopher J., Hovhannisyan Hayk, Bhat Ramesh A., Bodine Peter V.N., Komm Barry S., Javed Amjad, van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression, Journal of Biological Chemistry, 280, 39, 2005. Crossref
-
Zaidi Sayyed K., Young Daniel W., Montecino Martin, Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Architectural Epigenetics: Mitotic Retention of Mammalian Transcriptional Regulatory Information, Molecular and Cellular Biology, 30, 20, 2010. Crossref
-
Toda Hiroyuki, Yamamoto Masaya, Uyama Hiroshi, Tabata Yasuhiko, Effect of hydrogel elasticity and ephrinB2-immobilized manner on Runx2 expression of human mesenchymal stem cells, Acta Biomaterialia, 58, 2017. Crossref
-
Dieudonne François-Xavier, Sévère Nicolas, Biosse-Duplan Martin, Weng Jing-Jie, Su Yeu, Marie Pierre J., Promotion of Osteoblast Differentiation in Mesenchymal Cells Through Cbl-Mediated Control of STAT5 Activity, Stem Cells, 31, 7, 2013. Crossref
-
Zhang Jing, Li Ya-zhou, Chen Wen-qi, Yuan Jia-yu, Li Qian, Meng Yan-xin, Yu Ya-dong, Guo Qing, Genome sequencing identified a novel exonic microdeletion in the RUNX2 gene that causes cleidocranial dysplasia, Clinica Chimica Acta, 528, 2022. Crossref
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Ying Kai er, Feng Wenguang, Ying Wei-Zhong, Li Xingsheng, Xing Dongqi, Sun Yong, Chen Yabing, Sanders Paul W., Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4, Redox Biology, 52, 2022. Crossref
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Qiao Meng, Shapiro Paul, Fosbrink Matthew, Rus Horea, Kumar Rakesh, Passaniti Antonino, Cell Cycle-dependent Phosphorylation of the RUNX2 Transcription Factor by cdc2 Regulates Endothelial Cell Proliferation, Journal of Biological Chemistry, 281, 11, 2006. Crossref
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Mohanakrishnan Vishal, Balasubramanian Arumugam, Mahalingam Gokulnath, Partridge Nicola Chennell, Ramachandran Ilangovan, Selvamurugan Nagarajan, Parathyroid hormone‐induced down‐regulation of miR‐532‐5p for matrix metalloproteinase‐13 expression in rat osteoblasts, Journal of Cellular Biochemistry, 119, 7, 2018. Crossref
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Lengner Christopher J., Hassan Mohammad Q., Serra Ryan W., Lepper Christoph, van Wijnen Andre J., Stein Janet L., Lian Jane B., Stein Gary S., Nkx3.2-mediated Repression of Runx2 Promotes Chondrogenic Differentiation, Journal of Biological Chemistry, 280, 16, 2005. Crossref
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Galindo Mario, Pratap Jitesh, Young Daniel W., Hovhannisyan Hayk, Im Hee-Jeong, Choi Je-Yong, Lian Jane B., Stein Janet L., Stein Gary S., van Wijnen Andre J., The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G1-related Antiproliferative Function in Osteoblasts, Journal of Biological Chemistry, 280, 21, 2005. Crossref
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Chang Jia, Sonoyama Wataru, Wang Zhuo, Jin Qiming, Zhang Chengfei, Krebsbach Paul H., Giannobile William, Shi Songtao, Wang Cun-Yu, Noncanonical Wnt-4 Signaling Enhances Bone Regeneration of Mesenchymal Stem Cells in Craniofacial Defects through Activation of p38 MAPK, Journal of Biological Chemistry, 282, 42, 2007. Crossref
-
Hayashi Katsuhiro, Fang Xang, Ueda Hiroshi, Miwa Akihiro, Naka Toshiaki, Tsuchiya Hiroyuki, Bone Regeneration Using Autologous Adipose-Derived Stem Cell Spheroid Complex, Journal of Biomaterials and Tissue Engineering, 12, 6, 2022. Crossref
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Zhang Ying, Ling Ling, Ajay D/O Ajayakumar Arya, Eio Yating Michelle, van Wijnen Andre J., Nurcombe Victor, Cool Simon M., FGFR2 accommodates osteogenic cell fate determination in human mesenchymal stem cells, Gene, 818, 2022. Crossref
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Rojas Adriana, Aguilar Rodrigo, Henriquez Berta, Lian Jane B., Stein Janet L., Stein Gary S., van Wijnen Andre J., van Zundert Brigitte, Allende Miguel L., Montecino Martin, Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B, Journal of Biological Chemistry, 290, 47, 2015. Crossref
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Young Daniel W., Hassan Mohammad Q., Yang Xiao-Qing, Galindo Mario, Javed Amjad, Zaidi Sayyed K., Furcinitti Paul, Lapointe David, Montecino Martin, Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2, Proceedings of the National Academy of Sciences, 104, 9, 2007. Crossref
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Huang Mingwei, Li Xiaowen, Zhou Can, Si Min, Zheng Haiyan, Chen Lianhua, Ding Hongcheng, Noncoding RNA miR‐205‐5p mediates osteoporosis pathogenesis and osteoblast differentiation by regulating RUNX2, Journal of Cellular Biochemistry, 121, 10, 2020. Crossref
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Pratap Jitesh, Javed Amjad, Languino Lucia R., van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion, Molecular and Cellular Biology, 25, 19, 2005. Crossref
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Javed Amjad, Barnes George L., Pratap Jitesh, Antkowiak Tomasz, Gerstenfeld Louis C., van Wijnen Andre J., Stein Janet L., Lian Jane B., Stein Gary S., Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo , Proceedings of the National Academy of Sciences, 102, 5, 2005. Crossref
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Hassan Mohammad Q., Tare Rahul, Lee Suk Hee, Mandeville Matthew, Weiner Brian, Montecino Martin, van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., HOXA10 Controls Osteoblastogenesis by Directly Activating Bone Regulatory and Phenotypic Genes, Molecular and Cellular Biology, 27, 9, 2007. Crossref
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Zhao Chen, Hosoya Akihiro, Kurita Hiroshi, Hu Tao, Hiraga Toru, Ninomiya Tadashi, Yoshiba Kunihiko, Yoshiba Nagako, Takahashi Masafumi, Kurashina Kenji, Ozawa Hidehiro, Nakamura Hiroaki, Immunohistochemical study of hard tissue formation in the rat pulp cavity after tooth replantation, Archives of Oral Biology, 52, 10, 2007. Crossref
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Lin Tsung-Chieh, RUNX1 and cancer, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1877, 3, 2022. Crossref
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Sévère Nicolas, Miraoui Hichem, Marie Pierre J., The Casitas B Lineage Lymphoma (Cbl) Mutant G306E Enhances Osteogenic Differentiation in Human Mesenchymal Stromal Cells in Part by Decreased Cbl-mediated Platelet-derived Growth Factor Receptor α and Fibroblast Growth Factor Receptor 2 Ubiquitination, Journal of Biological Chemistry, 286, 27, 2011. Crossref
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Hamidouche Zahia, Fromigué Olivia, Ringe Jochen, Häupl Thomas, Vaudin Pascal, Pagès Jean-Christophe, Srouji Samer, Livne Erella, Marie Pierre J., Priming integrin α5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis, Proceedings of the National Academy of Sciences, 106, 44, 2009. Crossref
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Deng Li, Qing Wei, Lai Shuang, Zheng Jiajun, Liu Cong, Huang Hao, Peng Pairan, Mu Yandong, Differential Expression Profiling of microRNAs in Human Placenta-Derived Mesenchymal Stem Cells Cocultured with Grooved Porous Hydroxyapatite Scaffolds, DNA and Cell Biology, 41, 3, 2022. Crossref
-
Kurklu B, Whitehead R H, Ong E K, Minamoto T, Fox J G, Mann J R, Judd L M, Giraud A S, Menheniott T R, Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer, Oncogene, 34, 22, 2015. Crossref
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Jeong Byung-Chul, ATF3 mediates the inhibitory action of TNF-α on osteoblast differentiation through the JNK signaling pathway, Biochemical and Biophysical Research Communications, 499, 3, 2018. Crossref
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Miraoui Hichem, Oudina Karim, Petite Hervé, Tanimoto Yukiho, Moriyama Keiji, Marie Pierre J., Fibroblast Growth Factor Receptor 2 Promotes Osteogenic Differentiation in Mesenchymal Cells via ERK1/2 and Protein Kinase C Signaling, Journal of Biological Chemistry, 284, 8, 2009. Crossref
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Villanueva Francisco, Araya Hector, Briceño Pedro, Varela Nelson, Stevenson Andres, Jerez Sofia, Tempio Fabian, Chnaiderman Jonas, Perez Carola, Villarroel Milena, Concha Emma, Khani Farzaneh, Thaler Roman, Salazar‐Onfray Flavio, Stein Gary S, van Wijnen Andre J., Galindo Mario, The cancer‐related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis, Journal of Cellular Physiology, 234, 8, 2019. Crossref
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Schäffler Andreas, Büchler Christa, Concise Review: Adipose Tissue-Derived Stromal Cells—Basic and Clinical Implications for Novel Cell-Based Therapies, Stem Cells, 25, 4, 2007. Crossref
-
Yoon Won-Joon, Cho Young-Dan, Kim Woo-Jin, Bae Han-Sol, Islam Rabia, Woo Kyung-Mi, Baek Jeong-Hwa, Bae Suk-Chul, Ryoo Hyun-Mo, Prolyl Isomerase Pin1-mediated Conformational Change and Subnuclear Focal Accumulation of Runx2 Are Crucial for Fibroblast Growth Factor 2 (FGF2)-induced Osteoblast Differentiation, Journal of Biological Chemistry, 289, 13, 2014. Crossref
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Kurek Kyle C., Del Mare Sara, Salah Zaidoun, Abdeen Suhaib, Sadiq Hussain, Lee Suk-hee, Gaudio Eugenio, Zanesi Nicola, Jones Kevin B., DeYoung Barry, Amir Gail, Gebhardt Mark, Warman Matthew, Stein Gary S., Stein Janet L., Lian Jane B., Aqeilan Rami I., Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression, Cancer Research, 70, 13, 2010. Crossref
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Maeng Yong-Sun, Kwon Ja Young, Kim Eung Kweon, Kwon Young-Guen, Heterochromatin Protein 1 Alpha (HP1α: CBX5) is a Key Regulator in Differentiation of Endothelial Progenitor Cells to Endothelial Cells, Stem Cells, 33, 5, 2015. Crossref
-
Wang Fanhua, Liu Mingyao, Wang Ning, Luo Jian, G Protein-Coupled Receptors in Osteoarthritis, Frontiers in Endocrinology, 12, 2022. Crossref
-
Ofek Orr, Karsak Meliha, Leclerc Nathalie, Fogel Meirav, Frenkel Baruch, Wright Karen, Tam Joseph, Attar-Namdar Malka, Kram Vardit, Shohami Esther, Mechoulam Raphael, Zimmer Andreas, Bab Itai, Peripheral cannabinoid receptor, CB2, regulates bone mass, Proceedings of the National Academy of Sciences, 103, 3, 2006. Crossref
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Bauer Omri, Sharir Amnon, Kimura Ayako, Hantisteanu Shay, Takeda Shu, Groner Yoram, Loss of Osteoblast Runx3 Produces Severe Congenital Osteopenia, Molecular and Cellular Biology, 35, 7, 2015. Crossref
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Lu Xianghuai, Gilbert Linda, He Xiaofei, Rubin Janet, Nanes Mark S., Transcriptional Regulation of the Osterix (Osx, Sp7) Promoter by Tumor Necrosis Factor Identifies Disparate Effects of Mitogen-activated Protein Kinase and NFκB Pathways, Journal of Biological Chemistry, 281, 10, 2006. Crossref
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Zaidi Sayyed K., Pande Sandhya, Pratap Jitesh, Gaur Tripti, Grigoriu Simina, Ali Syed A., Stein Janet L., Lian Jane B., van Wijnen Andre J., Stein Gary S., Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential, Proceedings of the National Academy of Sciences, 104, 50, 2007. Crossref
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Aqeilan Rami I., Hassan Mohammad Q., de Bruin Alain, Hagan John P., Volinia Stefano, Palumbo Titziana, Hussain Sadiq, Lee Suk-Hee, Gaur Tripti, Stein Gary S., Lian Jane B., Croce Carlo M., The WWOX Tumor Suppressor Is Essential for Postnatal Survival and Normal Bone Metabolism, Journal of Biological Chemistry, 283, 31, 2008. Crossref
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Toda Hiroyuki, Yamamoto Masaya, Uyama Hiroshi, Tabata Yasuhiko, Fabrication of hydrogels with elasticity changed by alkaline phosphatase for stem cell culture, Acta Biomaterialia, 29, 2016. Crossref
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Liu Julie C., Lengner Christopher J., Gaur Tripti, Lou Yang, Hussain Sadiq, Jones Marci D., Borodic Brent, Colby Jennifer L., Steinman Heather A., van Wijnen Andre J., Stein Janet L., Jones Stephen N., Stein Gary S., Lian Jane B., Runx2 Protein Expression Utilizes the Runx2 P1 Promoter to Establish Osteoprogenitor Cell Number for Normal Bone Formation, Journal of Biological Chemistry, 286, 34, 2011. Crossref
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Kawate Hisaya, Wu Yin, Ohnaka Keizo, Takayanagi Ryoichi, Mutual transactivational repression of Runx2 and the androgen receptor by an impairment of their normal compartmentalization, The Journal of Steroid Biochemistry and Molecular Biology, 105, 1-5, 2007. Crossref
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Binay Sevgi, Kaptan Engin, Transcription factor Runx2 changes the expression of some matricellular proteins in metastatic breast cancer cells, Molecular Biology Reports, 49, 7, 2022. Crossref
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Hosoya Akihiro, Ninomiya Tadashi, Hiraga Toru, Yoshiba Kunihiko, Yoshiba Nagako, Kasahara Etsuo, Ozawa Hidehiro, Nakamura Hiroaki, Potential of Periodontal Ligament Cells to Regenerate Alveolar Bone, Journal of Oral Biosciences, 52, 2, 2010. Crossref
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Blecher Ronen, Krief Sharon, Galili Tal, Biton Inbal E., Stern Tomer, Assaraf Eran, Levanon Ditsa, Appel Elena, Anekstein Yoram, Agar Gabriel, Groner Yoram, Zelzer Elazar, The Proprioceptive System Masterminds Spinal Alignment: Insight into the Mechanism of Scoliosis, Developmental Cell, 42, 4, 2017. Crossref
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Hosoya Akihiro, Ninomiya Tadashi, Hiraga Toru, Zhao Chen, Yoshiba Kunihiko, Yoshiba Nagako, Takahashi Masafumi, Okabe Takahiro, Wakitani Shigeyuki, Yamada Hirohito, Kasahara Etsuo, Ozawa Hidehiro, Nakamura Hiroaki, Alveolar bone regeneration of subcutaneously transplanted rat molar, Bone, 42, 2, 2008. Crossref
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Lian Jane B., Stein Gary S., Montecino Martin, Stein Janet L., van Wijnen Andre J., Genetic and Epigenetic Control of the Regulatory Machinery for Skeletal Development and Bone Formation: Contributions of Vitamin D3, in Vitamin D, 2011. Crossref
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Hong Deli, Fritz Andrew J., Gordon Jonathan A., Tye Coralee E., Boyd Joseph R., Tracy Kirsten M., Frietze Seth E., Carr Frances E., Nickerson Jeffrey A., Van Wijnen Andre J., Imbalzano Anthony N., Zaidi Sayyed K., Lian Jane B., Stein Janet L., Stein Gary S., RUNX1‐dependent mechanisms in biological control and dysregulation in cancer, Journal of Cellular Physiology, 234, 6, 2019. Crossref
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Otálora-Otálora Beatriz Andrea, González Prieto Cristian, Guerrero Lucia, Bernal-Forigua Camila, Montecino Martin, Cañas Alejandra, López-Kleine Liliana, Rojas Adriana, Identification of the Transcriptional Regulatory Role of RUNX2 by Network Analysis in Lung Cancer Cells, Biomedicines, 10, 12, 2022. Crossref