Abonnement à la biblothèque: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Publication de 6  numéros par an

ISSN Imprimer: 1045-4403

ISSN En ligne: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Antiretroviral Agents: Looking for the Best Possible Chemotherapeutic Options to Conquer HIV

Volume 26, Numéro 4, 2016, pp. 363-381
DOI: 10.1615/CritRevEukaryotGeneExpr.2016018255
Get accessGet access

RÉSUMÉ

For the last thirty years, ongoing efforts have revolutionized the antiretroviral therapy, which changed human immunodeficiency virus (HIV) infections from terrifying lethal diseases to chronic conditions. However, many challenges, like emergence of drug resistance, limited the scope of activity of currently existing anti-HIV agents. Quite often severe side effects and lifelong dependency are the major concerns of present era. All these issues have compelled the scientists to reconsider and refine the current therapies and also contemplate the pivotal priorities for the developments of novel therapeutic paradigms. In response to this global concern, medicinal chemists and pharmaceutical scientists have put in solid efforts to search for or develop novel, more effective, safer, and affordable antiretroviral agents for the treatment of HIV infections. The exploration and utilization of natural sources has always been an attractive research area in this regard. In the search of the most suitable and potent anti-HIV agents, researchers have explored the anti-HIV activity of different classes of compounds originating from plants, marine organisms, and microorganisms. This review will highlight the recent notable developments for the discovery of antiretroviral agents. Furthermore, this review also highlights the better in-depth insights of existing HIV cures and preventive strategies.

CITÉ PAR
  1. Qadir Muhammad Imran, Hepatitis in AIDS patients, Reviews in Medical Virology, 28, 1, 2018. Crossref

  2. Chinsembu Kazhila C., Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants, Revista Brasileira de Farmacognosia, 29, 4, 2019. Crossref

  3. Adeleke Bartholomew, Babalola Olubukola, Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review, Journal of Fungi, 7, 2, 2021. Crossref

  4. Li Min, Wang Qunwei, Shen Yinzhong, Adherence predictor variables in AIDS patients: an empirical study using the data mining-based RFM model, AIDS Research and Therapy, 18, 1, 2021. Crossref

  5. Saini Manpreet Kaur, Capalash Neena, Varghese Eldho, Kaur Charanjit, Singh Sukhvinder Pal, A Targeted Metabolomics Approach to Study Secondary Metabolites and Antioxidant Activity in ‘Kinnow Mandarin’ during Advanced Fruit Maturity, Foods, 11, 10, 2022. Crossref

  6. Dhara Amal Kumar, Nayak Amit Kumar, Introduction to antiviral therapy, in Viral Infections and Antiviral Therapies, 2023. Crossref

Prochains articles

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections Prix et politiques d'abonnement Begell House Contactez-nous Language English 中文 Русский Português German French Spain