Publication de 6 numéros par an
ISSN Imprimer: 1045-4403
ISSN En ligne: 2162-6502
Indexed in
Antiretroviral Agents: Looking for the Best Possible Chemotherapeutic Options to Conquer HIV
RÉSUMÉ
For the last thirty years, ongoing efforts have revolutionized the antiretroviral therapy, which changed human immunodeficiency virus (HIV) infections from terrifying lethal diseases to chronic conditions. However, many challenges, like emergence of drug resistance, limited the scope of activity of currently existing anti-HIV agents. Quite often severe side effects and lifelong dependency are the major concerns of present era. All these issues have compelled the scientists to reconsider and refine the current therapies and also contemplate the pivotal priorities for the developments of novel therapeutic paradigms. In response to this global concern, medicinal chemists and pharmaceutical scientists have put in solid efforts to search for or develop novel, more effective, safer, and affordable antiretroviral agents for the treatment of HIV infections. The exploration and utilization of natural sources has always been an attractive research area in this regard. In the search of the most suitable and potent anti-HIV agents, researchers have explored the anti-HIV activity of different classes of compounds originating from plants, marine organisms, and microorganisms. This review will highlight the recent notable developments for the discovery of antiretroviral agents. Furthermore, this review also highlights the better in-depth insights of existing HIV cures and preventive strategies.
-
Qadir Muhammad Imran, Hepatitis in AIDS patients, Reviews in Medical Virology, 28, 1, 2018. Crossref
-
Chinsembu Kazhila C., Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants, Revista Brasileira de Farmacognosia, 29, 4, 2019. Crossref
-
Adeleke Bartholomew, Babalola Olubukola, Pharmacological Potential of Fungal Endophytes Associated with Medicinal Plants: A Review, Journal of Fungi, 7, 2, 2021. Crossref
-
Li Min, Wang Qunwei, Shen Yinzhong, Adherence predictor variables in AIDS patients: an empirical study using the data mining-based RFM model, AIDS Research and Therapy, 18, 1, 2021. Crossref
-
Saini Manpreet Kaur, Capalash Neena, Varghese Eldho, Kaur Charanjit, Singh Sukhvinder Pal, A Targeted Metabolomics Approach to Study Secondary Metabolites and Antioxidant Activity in ‘Kinnow Mandarin’ during Advanced Fruit Maturity, Foods, 11, 10, 2022. Crossref
-
Dhara Amal Kumar, Nayak Amit Kumar, Introduction to antiviral therapy, in Viral Infections and Antiviral Therapies, 2023. Crossref