Abonnement à la biblothèque: Guest
International Journal of Physiology and Pathophysiology

Publication de 4  numéros par an

ISSN Imprimer: 2155-014X

ISSN En ligne: 2155-0158

SJR: 0.116

Oxidative Stress in a Cardiovascular System of Rats with Persistent Deficiency of Cerebral Dopamine

Volume 1, Numéro 1, 2010, pp. 17-24
DOI: 10.1615/IntJPhysPathophys.v1.i1.30
Get accessGet access

RÉSUMÉ

Physiological significance of cardiac mitochondrial reactive oxygen species (ROS) regulation is still unknown. In the current study, mitochondrial ROS (O2 and OH) generation, stabile H2O2 and lipids peroxidation marker (malonic dialdehyde, MDA) pools, as well as pools of potent antioxidants − urea and uric acid − were determined in rat heart, miocardial mitochondria and in blood plasma and erythrocytes at low 44% and high 96% levels of cerebral dopamine-synthesis neurons destruction (by 6-hydroxidopamine treatment). In the untreated rats ROS generation, H2O2 and MDA levels were low but in rats with chronic 3−4 month deficiency of cerebral dopamine synthesis by nigro-striatal dopaminergic system ROS generation and lipids peroxidation were progressively increased. Dopamine deficiency can improve mitochondrial efficiency of oxidative phosphorylation due to oxidative stress.

364 Vues d'articles 9 Téléchargements d'articles Métrique
364 VUES 9 TÉLÉCHARGEMENTS Google
Scholar
CITATIONS

Articles avec un contenu similaire:

Age-Associated Mitochondrial Dysfunction in the Heart Accompanied by Constitutive NO-Synthases Uncoupling on the Background of Oxidative and Nitrosative Stress International Journal of Physiology and Pathophysiology, Vol.8, 2017, issue 2
Nataliya A. Strutynska, Lidiya A. Mys, Alina Yu. Budko, Vadim F. Sagach, Anatoliy V. Kotsuruba
Propargylglycine Restores Endothelium-Dependent Relaxation of Aortic Smooth Muscle in Old Rats International Journal of Physiology and Pathophysiology, Vol.6, 2015, issue 3
Lyubov G. Stepanenko, Konstantin O. Drachuk, Olga V. Bazilyuk, Vadim F. Sagach, Anatoliy V. Kotsuruba
Changes in Myocardium Metabolism in Ischemia-Reperfusion and Activation of ATP-Sensitive Potassium Channels International Journal of Physiology and Pathophysiology, Vol.3, 2012, issue 3
Olexiy O. Moibenko, Roman A. Rovenets, Ruslan B. Strutynskyi, Anatoliy V. Kotsuruba, Anatolii P. Neshcheret
Fruiting Bodies of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes) Alleviate Diabetes-Associated Oxidative Stress International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 1
Chien-Hsing Lee, Wen-Tzu Wu, Tai-Hao Hsu, Hui-Chen Lo
Reactive Nitrogen and Oxygen Species Metabolism in Rat Heart Mitochondria under Administration of Nitric Oxide Donor in Vivo International Journal of Physiology and Pathophysiology, Vol.3, 2012, issue 4
Yulia P. Korkach, Vadim F. Sagach, Anatoliy V. Kotsuruba, Lyudmila I. Kolchinskaya, Olga V. Akopova

Dernier numéro

Systemic Toxic Dental Sealant-Induced Effect on Nervous Tissue in vitro O. A. Znachkova, Irina V. Lushnikova, Galina G. Skibo, M. Y. Antonenko, Nana V. Voitenko Impact of Various Polyphenols on Disturbance of Cholesterol Metabolism under Insulin Resistance V. P. Fylymonenko, A. L. Zagayko Target Correction of Mitochondrial Dysfunction in Parkinson's Disease by Capicor Iryna M. Mankovska, Kateryna V. Rosova, Olga O. Gonchar, Valentina I. Nosar, Larisa. V. Bratus, Tetyana I. Drevitska, Ivan D. Glazyrin, Nina V. Karasevich, Iryna M. Karaban Changes in Ongoing Activity and Electrophysiological Characteristics of the Rat Retinal Ganglion Cells in Diabetes Mellitus N. Ya. Martyniuk, V. Yu. Maslov, Helen E. Purnyn, Svetlana A. Fedulova, Nikolai S. Veselovsky Sex Characteristics of Hydrogen Sulfide Effect on Ischemia-Reperfusion in Rat Myocardium Andrii V. Melnyk, Nataliia V. Zaichko, Oleksii A. Khodakovskyi, Olga V. Khodakivska Cardiohemodynamic Changes in Focal Cerebral Ischemia Roman R. Sharipov, Nataliya A. Dorofeyeva, Vadim F. Sagach Cerebral Hemodynamics and Electroencephalographic Pattern in Patients with Symptomatic Epilepsy at Combined Treatment with Transcranial Direct Current Stimulation Kateryna V. Yatsenko Physiological Endurance of Skeletal Muscle Increases under C60 Fullerene Application before Physical Load Tetyana Yu. Matvienko, Danylo Zavodovskiy, Iryna V. Mishchenko, Kateryna I. Bogutska, Yuriy I. Prylutskyy, Sofia Paradizova, Larisa Bezuh, Uwe Ritter, Peter Scharff Possible Mechanisms Underlying Association between Thyroiditis and Thyroid Papillary Carcinoma Tamara M. Myshunina, Mykola D. Tronko Index, Volume 9, 2018
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections Prix et politiques d'abonnement Begell House Contactez-nous Language English 中文 Русский Português German French Spain