Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
International Journal of Physiology and Pathophysiology
SJR: 0.106

ISSN Imprimer: 2155-014X
ISSN En ligne: 2155-0158

Archives: Volume 1, 2010 to Volume 9, 2018

International Journal of Physiology and Pathophysiology

DOI: 10.1615/IntJPhysPathophys.v8.i2.10
pages 99-109

Induction of Oxidative and Nitrosative Stress in Young Males in Adapting to Muscular Load during Training and Competitive Periods

Nadiia V. Bogdanovs'ka
Zaporizhye National University, Zaporozhye, Ukraine
Anatoliy V. Kotsuruba
Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Anastasiia V. Symonik
Zaporizhye National University, Zaporozhye, Ukraine

RÉSUMÉ

We studied the features of oxidative and nitrosative stress development in apparently healthy subjects under the influence of long-term high volume and intensity exercise. It has been shown that the young males who systematically perform muscular work are characterized by high levels of markers for the formation of superoxide radical, reactive oxygen species, lipid peroxidation products, and nitrosative stress. The increase in the degree of adverse effects of intensive training and competitive loads on the body is accompanied by pronounced adaptive changes in the hierarchy of oxidative inducible de novo synthesis of nitric oxide (increased three times), as well as its non-oxidative 'salvage' synthesis (growth 3 times). Disadaptation of the body at the end of a competition period is evidenced by increasing reactive oxygen species generation (superoxide radical 3.5 times and hydrogen peroxide 2.5 times), as well as the products of purine nucleotide degradation 2 times, and the increase in the content of the nitrate anion 2.5 times.


Articles with similar content:

Age-Associated Mitochondrial Dysfunction in the Heart Accompanied by Constitutive NO-Synthases Uncoupling on the Background of Oxidative and Nitrosative Stress
International Journal of Physiology and Pathophysiology, Vol.8, 2017, issue 2
Nataliya A. Strutynska, Lidiya A. Mys, Alina Yu. Budko, Vadim F. Sagach, Anatoliy V. Kotsuruba
Rising of Constitutive NO-Synthase Coupling and Hemoglobin Content in Erythrocytes of Old Animals by Iron- Containing Herbal Drug
International Journal of Physiology and Pathophysiology, Vol.8, 2017, issue 3
S. I. Uretii, Anatoliy V. Kotsuruba, Bogdan S. Kopyak
Changes in Arginase-Nitric Oxide Synthase System at Adaptation to Prolonged Exercise Training by Swimming in Adult and Aged Rat Hearts
International Journal of Physiology and Pathophysiology, Vol.3, 2012, issue 4
Yulia P. Korkach, Lyubov G. Stepanenko, Olga V. Bazilyuk, Vadim F. Sagach, Anatoliy V. Kotsuruba, Sergiy O. Talanov
Long-term Exercise Training Improves Heart Function in Rats by NO-Dependent Decrease in Mitochondrial Pore Sensitivity to Calcium
International Journal of Physiology and Pathophysiology, Vol.7, 2016, issue 1
Snizhana V. Chorna, Nataliya A. Strutynska, Viktor E. Dosenko, Galyna L. Vavilova, Vadim F. Sagach, Anatoliy V. Kotsuruba, Olena M. Semenykhina, Sergiy O. Talanov
The Ways of Lipid Peroxidation and Protein Activation in Chronic Kidney Disease
International Journal of Physiology and Pathophysiology, Vol.7, 2016, issue 3
Lesya V. Korol