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International Journal of Physiology and Pathophysiology
SJR: 0.106

ISSN Imprimer: 2155-014X
ISSN En ligne: 2155-0158

Archives: Volume 1, 2010 to Volume 9, 2018

International Journal of Physiology and Pathophysiology

DOI: 10.1615/IntJPhysPathophys.v5.i4.10
pages 283-290

Morphofunctional Changes in Thyroid Gland Induced by Normobaric Hypoxia in Young Rats

Roman V. Yanko
Bogomoletz Institute of Physiology of the National Academy of Sciences of Ukraine, Kyiv

RÉSUMÉ

Effects of hypoxic gas mixture in different modes (HGM; 10% oxygen in nitrogen) on the morphometric changes in the functional activity of the thyroid parenchymatous tissue in 3-month-old rats were studied. Hypoxia-induced decrease in the average cross-sectional areas of a follicle and colloid, reduced follicle inner diameter, increased thyroid epithelium height, an increase in a number of thyrocytes in a follicle, resorption vacuoles and interfollicular islets, enhanced follicle-colloid index and decreased colloid accumulation index have been shown. Thus, dosed normobaric hypoxia intensifies functional activity and physiological regeneration processes in the thyroid gland of the young animals.


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