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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Teratogenic and Toxic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.) P. Karst. (Higher Basidiomycetes), on Zebrafish Embryo as Model

Volume 14, Numéro 5, 2012, pp. 507-512
DOI: 10.1615/IntJMedMushr.v14.i5.90
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RÉSUMÉ

This paper highlights the teratogenic and toxic effects of Ganoderma lucidum (Lingzhi or Reishi mushroom) extract on zebrafish embryos. Hatchability, malformations, and lethality rate of zebrafish embryos were assessed to provide valuable information regarding the potential teratogenic activity of G. lucidum. Hatching was completed 48 h post treatment application (hpta) at 1% or lower concentrations of extract and embryo water. The hatching rate of embryos treated with 5% or higher concentrations was significantly lower (p> 0.05) than the control. Tail malformation was the most marked morphological abnormality in embryos at 72 hpta, which was obviously caused by 1% extract (55.56% tail malformation) and was observed in all embryos exposed to 5% of extract. Growth retardation was evident in embryos exposed to 5%, 10%, and 20%. However, lethal effect of extract of G. lucidum was dependent on dose and time of exposure. Mortality rates of embryos treated with 5% (44.44%) or higher concentrations of the extract was significantly higher (p > 0.05) than that of the control embryos at 72 hpta. These results suggest that G. lucidum extract has lethal and sub-lethal effects on zebrafish embryos.

CITÉ PAR
  1. Kamaraj Chinnaperumal, Deepak Paramasivam, Balasubramani Govindasamy, Karthi Sengodan, Arul Dhayalan, Aiswarya Dilipkumar, Amutha Vadivel, Vimalkumar Elangovan, Mathivanan Damodaran, Suseem Sundaram Renjitham, Muthu-Pandian Chanthini Kanagaraj, Senthil-Nathan Sengottayan, Perumal Pachiappan, Target and non-target toxicity of fern extracts against mosquito vectors and beneficial aquatic organisms, Ecotoxicology and Environmental Safety, 161, 2018. Crossref

  2. Su Jiyan, Su Lu, Li Dan, Shuai Ou, Zhang Yifan, Liang Huijia, Jiao Chunwei, Xu Zhanchi, Lai Yong, Xie Yizhen, Antitumor Activity of Extract From the Sporoderm-Breaking Spore of Ganoderma lucidum: Restoration on Exhausted Cytotoxic T Cell With Gut Microbiota Remodeling, Frontiers in Immunology, 9, 2018. Crossref

  3. Sharma Purva, Tulsawani Rajkumar, Agrawal Usha, Pharmacological effects of Ganoderma lucidum extract against high‐altitude stressors and its subchronic toxicity assessment , Journal of Food Biochemistry, 43, 12, 2019. Crossref

  4. Ahmad Md Faruque, Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement, Biomedicine & Pharmacotherapy, 107, 2018. Crossref

  5. Cruz Mycheli P. da, Larentis Lucas T., Vismara Edgar de S., Vismara Lilian de S., Freitas Patricia F. de, Mazaro Sérgio M., Action of Ganoderma lucidum mycelial growth filtrates on Erysiphe diffusa and embryotoxicity assessment in a chicken embryo model, Acta Biologica Szegediensis, 65, 1, 2021. Crossref

  6. Suryamathi Mathiazhagan, Viswanathamurthi Periasamy, Vennila Krishnan, Palvannan Thayumanavan, Bertani Roberta, Sgarbossa Paolo, Tyrosinase Immobilized Zein Nanofibrous Matrix as a Green and Recyclable Material for Biodegradation of Azo Dyes, Fibers and Polymers, 22, 10, 2021. Crossref

  7. Abd Rashid Nur Ayuni, Lau Beng Fye, Kue Chin Siang, Differential toxicity and teratogenic effects of the hot water and cold water extracts of Lignosus rhinocerus (Cooke) Ryvarden sclerotium on zebrafish (Danio rerio) embryos, Journal of Ethnopharmacology, 285, 2022. Crossref

  8. Mahmood Ibrahim, Azfaralariff Ahmad, Mohamad Azhar, Airianah Othman B., Law Douglas, Dyari Herryawan Ryadi Eziwar, Lim Yi Chieh, Fazry Shazrul, Mutated Shiitake extracts inhibit melanin-producing neural crest-derived cells in zebrafish embryo, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 245, 2021. Crossref

  9. Wan-Mohtar Wan Abd Al Qadr Imad, Ilham Zul, Jamaludin Adi Ainurzaman, Rowan Neil, Use of Zebrafish Embryo Assay to Evaluate Toxicity and Safety of Bioreactor-Grown Exopolysaccharides and Endopolysaccharides from European Ganoderma applanatum Mycelium for Future Aquaculture Applications, International Journal of Molecular Sciences, 22, 4, 2021. Crossref

  10. Zhang Yun, Xia Qing, Wang Jiabo, Zhuang Kaiyan, Jin Hongtao, Liu Kechun, Progress in using zebrafish as a toxicological model for traditional Chinese medicine, Journal of Ethnopharmacology, 282, 2022. Crossref

  11. Ahmad Rizwan, Riaz Muhammad, Khan Aslam, Aljamea Ahmed, Algheryafi Mohammad, Sewaket Deya, Alqathama Aljawharah, Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties , Phytotherapy Research, 35, 11, 2021. Crossref

  12. Ahmad Md Faruque, Wahab Shadma, Ahmad Fakhruddin Ali, Ashraf Syed Amir, Abullais Shahabe Saquib, Saad Hisham H., Ganoderma lucidum: A potential pleiotropic approach of ganoderic acids in health reinforcement and factors influencing their production, Fungal Biology Reviews, 39, 2022. Crossref

  13. Mohan Kannan, Karthick Rajan Durairaj, Muralisankar Thirunavukkarasu, Ramu Ganesan Abirami, Marimuthu Kasi, Sathishkumar Palanivel, The potential role of medicinal mushrooms as prebiotics in aquaculture: A review, Reviews in Aquaculture, 14, 3, 2022. Crossref

  14. Taufek Norhidayah Mohd, Harith Hanis H., Abd Rahim Muhamad Hafiz, Ilham Zul, Rowan Neil, Wan-Mohtar Wan Abd Al Qadr Imad, Performance of mycelial biomass and exopolysaccharide from Malaysian Ganoderma lucidum for the fungivore red hybrid Tilapia (Oreochromis sp.) in Zebrafish embryo, Aquaculture Reports, 17, 2020. Crossref

  15. Abdullah Nur Raihan, Mohd Nasir Mohd Hamzah, Azizan Nur Hafizah, Wan-Mohtar Wan Abd Al Qadr Imad, Sharif Faez, Bioreactor-grown exo- and endo-β-glucan from Malaysian Ganoderma lucidum: An in vitro and in vivo study for potential antidiabetic treatment, Frontiers in Bioengineering and Biotechnology, 10, 2022. Crossref

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