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International Journal of Medicinal Mushrooms
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ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

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International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v7.i3.330
pages 382-383

Study of Antiprotozoal Activity and Mitogenic Effects Within Some Medicinal Mushrooms

Susanna M. Badalyan
Laboratory of Fungal Biology and Biotechnology, Institute of Pharmacy, Yerevan State University, 1 A. Manoogian St., 0025 Yerevan, Armenia
S. H. Sisakyan
Laboratory of Fungal Biology and Biotechnology, Yerevan State University, Department of Botany, 1 Aleg Manoogian St., 375025; M. Heratzi Yerevan State Medical University, Department of Medical Biology and Genetics, 2 Koryun St., 375025, Yerevan, Armenia


Many mushrooms possess both excellent nutritional values and pharmaceutical properties. Since ancient times, medicinal mushrooms have been used in traditional medicine of Asian countries. Isolated and identified substances, particularly from Lentinus edodes (Berk.) Singer, Coprinus comatus (O.F.Müll.) S.F.Gray, and Flammulina velutipes (W.Curt.:Fr.) Singer are used in the treatment of immune system disorders, cancer, bacterial, viral, and fungal infections, etc. They are able to decrease high glucose and lipid levels in the blood and are recommended as neuro- and vasotonics, hepatoprotective and thrombolytic agents. However, the antiprotozoal and mitogenic activities of mushrooms have not been sufficiently investigated yet. Presented results, as a part of our Medicinal Mushrooms Myco-Pharmacological Screening Program (MMMPSP), concern the study of the antiprotozoal activity (APA) and mitogenic effects (MGE) of mycelium and fruiting bodies (FB) samples of Lentinus edodes, Coprinus comatus, and Flammulina velutipes.

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