Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
International Journal of Medicinal Mushrooms
Facteur d'impact: 1.423 Facteur d'impact sur 5 ans: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v9.i1.20
pages 7-14

Evaluation of Therapeutic Activity of Hypogeous Ascomycetes and Basidiomycetes from North America

Rita Stanikunaite
Department of Pharmacognosy, The University of Mississippi, University, MS, USA
James M. Trappe
Department of Forest Service, Oregon State University, Corvallis, Oregon 97331-5257, USA
Shabana I. Khan
National Center for Natural Products Research, The University of Mississippi, University, MS, USA
Samir A. Ross
Department of Pharmacognosy and National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi 38677

RÉSUMÉ

This study is the first broad investigation of therapeutic activities of hypogeous truffles and truffle-like fungi (Ascomycetes and Basidiomycetes) from North America. Twenty-two species from 12 families were evaluated in several biological assays for antimicrobial, antimalarial, antiinflammatory, antioxidant, antituberculosis, and anticancer activities. Biological screening results indicate that 1 species showed antimalarial activity, 11 species were active in antioxidant assay, 9 species were active in antiinflammatory assay, 9 species showed antituberculosis activity, and 2 species showed anticancer activity. Among the screened species, Elaphomyces granulatus, E. muricatus, Geopora clausa, Hymenogaster subalpinus, Melanogaster tuberiformis, Rhizopogon couchii, R. nigrescens, R. pedicellus, R. subaustralis, R. subgelatinosus, and Scleroderma laeve expressed therapeutic activity in more than one assay. Our results indicate that this group of fungi has promising therapeutic activities that could lead to the development of new agents for the treatment and prevention of diseases.


Articles with similar content:

Studies of the Antimicrobial Activity of Mushrooms (Agaricales) from South America (Review)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 11
Roberta Paulert, Marina Giombelli Rosenberger, Vagner G. Cortez
Antiproliferative Activity of Some Higher Mushrooms from Hungary against Human Cancer Cell Lines
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 12
Attila Vanyolos, Istvan Zupko, Noemi Bozsity, Judit Hohmann, Bernadett Kovacs
Anti-inflammatory Activity of Mycelial Extracts from Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 4
Hong-Yu Xu, Zhenming Lu, Yan Geng, Zheng-Hong Xu, Jin-Song Shi, Shuiling Zhu
Antiproliferative and Antioxidant Activities of Wild Boletales Mushrooms from France
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 1
Caroline Guzman, Patrick Poucheret, Manon Vitou, Stéphanie Arnould, Frédéric Boudard, Sylvie Rapior, Sylvie Morel, Françoise Fons
The Efficacy and Toxicity of Using the Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Its Products in Chemotherapy (Review)
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 10
Martina Cizmarikova