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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

A Review of Pharmacological Activities of Mushroom Polysaccharides

Volume 1, Numéro 3, 1999, pp. 195-206
DOI: 10.1615/IntJMedMushrooms.v1.i3.10
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RÉSUMÉ

In the last few decades, mushrooms have increasingly been used as a source of therapeutic agents or health food supplements. In particular, polysaccharides or polysaccharide-protein complexes derived from mushrooms have received much attention in biomedical research. These bioactive biopolymers are mainly present as glucans with different types of glycosidic linkages, such as (1→3), (1→6)-β-glucans and (1→3)-α-gtucans, while others mostly bind to protein residues as polysaccharide-protein complexes. One of the most promising activities of these polysaccharides is their immunomodulation and anticancer effect. Three antitumor polysaccharides, namely lentinan, schizophyllan, and protein-bound polysaccharide (or polysaccharopeptide), have been isolated from Lentinus edodes (Berk.) Sing., Schizophyllum commune (Fr.: Fr.), and Coriolus versicolor (L.: Fr.) Quel. [= Trametes versicolor (L.: Fr.) Lloyd], respectively, and have become large nutraceutical and pharmaceutical market items, particularly in Japan. The mechanism of their antitumor actions is still not completely understood. But it is widely accepted that antitumor polysaccharides from higher fungi enhance various immune responses in vivo and in vitro, and act as biological response modifiers. Potentiation of the host defense system may result in the activation of many kinds of immune cells that are vitally important for the maintenance of homeostasis. In addition to immunomodulation and antitumor activity, there are new potential applications of mushroom polysaccharides or polysaccharide-protein complexes for pharmaceutical and functional food development. These polysaccharides have been shown to have various potent pharmacological properties, such as antioxidant, free radical scavenging, antiviral, hepatoprotective, antifibrotic, antiinflammatory, antidiabetes, and hypocholesterolemic activities.

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