Publication de 12 numéros par an
ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
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Antiproliferative Activity of Some Higher Mushrooms from Hungary against Human Cancer Cell Lines
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RÉSUMÉ
In the present work, aqueous and organic extracts of 16 Basidiomycetes mushrooms and 1 Ascomycetes mushroom were investigated in vitro for their antiproliferative activity against HeLa (cervix epithelial adenocarcinoma), A431 (skin epidermoid carcinoma), A2780 (ovarian carcinoma), and MCF7 (breast epithelial adenocarcinoma) cells, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. A total of 68 n-hexane, chloroform, 50% methanol, and water extracts of selected species were screened for their potential cell growth inhibitory activity. Our experiments revealed that 7 of 17 species demonstrated notable antiproliferative activity (at least 50% inhibition of cell proliferation) against one or more cell lines. Kuehneromyces mutabilis, Lactarius quietus, and Lentinellus cochleatus, which exerted the highest activity on cancer cells, are considered valuable species in the perspective of further mycochemical studies.
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Kovács Bernadett, Béni Zoltán, Dékány Miklós, Orbán-Gyapai Orsolya, Sinka Izabella, Zupkó István, Hohmann Judit, Ványolós Attila, Chemical Analysis of the Edible Mushroom Tricholoma populinum: Steroids and Sulfinyladenosine Compounds, Natural Product Communications, 12, 10, 2017. Crossref
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Nowakowski Patryk, Markiewicz-Żukowska Renata, Bielecka Joanna, Mielcarek Konrad, Grabia Monika, Socha Katarzyna, Treasures from the forest: Evaluation of mushroom extracts as anti-cancer agents, Biomedicine & Pharmacotherapy, 143, 2021. Crossref
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Noviyanti Nita, Mahardhika Wahyu Aji, Tri Lunggani Arina, Permana Putra Ivan , MACROFUNGI INVENTARITATION AT THE PINE FOREST OF KRAGILAN, MAGELANG, BIOVALENTIA: Biological Research Journal, 8, 2, 2022. Crossref