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International Journal of Medicinal Mushrooms
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ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

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International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v17.i10.20
pages 921-932

Current Advances in the Antimicrobial Potential of Species of Genus Ganoderma (Higher Basidiomycetes) against Human Pathogenic Microorganisms (Review)

Mahendra K. Rai
Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra-444 602, India
Swapnil Gaikwad
Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra 444602, India
Dipali Nagaonkar
Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India
Carolina Alves dos Santos
Post Graduate Program in Pharmaceutical Sciences, Department of Development and Evaluation of Bioactive Substances, University of Sorocaba, SP, Brazil


Ganoderma spp. are very important therapeutic mushrooms and have been used traditionally for 4000 years in the treatment of various human disorders. Different species of Ganoderma possess bioactive compounds, which have already demonstrated antiviral, antibacterial, and antifungal activities. Various bioactive compounds such as triterpenoids, colossolactones, and polysaccharides, which are responsible for the antimicrobial potential of the genus, are discussed here in detail. Some Ganoderma spp. have been reported to be potential agents for the synthesis of metal nanoparticles. These nanoparticles have demonstrated antimicrobial activity and also are reviewed herein. The main aim of this review is to discuss the possible use of Ganoderma extracts and their active principles in antimicrobial therapy.