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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Comparative Cytotoxicity and Hemagglutination Activities of Crude Protein Extracts from Culinary-Medicinal Mushrooms

Volume 12, Numéro 2, 2010, pp. 213-222
DOI: 10.1615/IntJMedMushr.v12.i2.130
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RÉSUMÉ

The bioactivities of crude protein extracts from three commercial culinary-medicinal mushrooms, Flammulina velutipes, Pleurotus citrinopileatus, and Hericium erinaceus, were compared in this study to determine the presence of new and effective anticancer and immunomodulatory agents in these mushroom species. F. velutipes was used as a reference mushroom for its fungal immunomodulatory protein (FIP-fve), reported to exhibit potent mitogenic, cytotoxicity, and hemagglutination activities. The total yield of crude protein extracts obtained from F. velutipes, P. citrinopileatus, and H. erinaceus were 0.255, 0.501, and 0.369 mg/g of fresh fruiting bodies, respectively. SDS-PAGE profile analysis for protein bands having molecular weight in the range reported for the FIPs family revealed that F. velutipes and P. citrinopileatus crude protein extracts contained a distinct 13-kDa FIP-fve and a 15-kDa FIP from P. citrinopileatus (PCiP), respectively. However, faint 10- to 14-kDa protein bands were observed in crude extract from H. erinaceus. Crude protein extracts of F. velutipes, P. citrinopileatus, and H. erinaceus showed cytotoxicity on human cervical cancer HeLa cells at IC50 concentrations of 10.0, 21.6, and 31.2 μg/mL, respectively. The trypan blue exclusion assay further confirmed that protein extracts from F. velutipes and P. citrinopileatus, compared to H. erinaceus, showed significantly higher cytotoxicity on HeLa cells. Of the three species studied, only F. velutipes crude extract caused hemagglutination of human whole blood cells, possibly due to the FIP-fve. As there are no previous reports of cytotoxicity of these mushrooms on HeLa cells, our findings provided new insights into the presence of potential anticancer components in these mushrooms, which can be subsequently purified for further analysis and identification.

CITÉ PAR
  1. Jiang Shengjuan, Wang Songhua, Sun Yujun, Zhang Qiang, Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals, Applied Microbiology and Biotechnology, 98, 18, 2014. Crossref

  2. Thongbai Benjarong, Rapior Sylvie, Hyde Kevin D., Wittstein Kathrin, Stadler Marc, Hericium erinaceus, an amazing medicinal mushroom, Mycological Progress, 14, 10, 2015. Crossref

  3. Pushparajah V., Fatima A., Chong C. H., Gambule T. Z., Chan C. J., Ng S. T., Tan C. S., Fung S. Y., Lee S. S., Tan N. H., Lim R. L. H., Characterisation of a New Fungal Immunomodulatory Protein from Tiger Milk mushroom, Lignosus rhinocerotis, Scientific Reports, 6, 1, 2016. Crossref

  4. Yuan Biao, Ma Ning, Zhao Liyan, Zhao Ermin, Gao Zili, Wang Weicang, Song Mingyue, Zhang Guodong, Hu Qiuhui, Xiao Hang, In vitro and in vivo inhibitory effects of a Pleurotus eryngii protein on colon cancer cells, Food & Function, 8, 10, 2017. Crossref

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