Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
International Journal of Medicinal Mushrooms
Facteur d'impact: 1.423 Facteur d'impact sur 5 ans: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v3.i4.80
34 pages

Higher Basidiomycota as a Source of Antitumor and Immunostimulating Polysaccharides (Review)

Sergey V. Reshetnikov
N. G. Kholodny Institute of Botany, National Academy of Sciences of Ukraine, 2 Tereshchenkivskaya Str., Kiev 252001, Ukraine; and Med Myco Ltd., Institute of Evolution, University of Haifa, Mt. Carmel, Haifa 31905, Israel
Kok- Kheng Tan
MycoBiotech Pte Ltd 12 Science Park Drive # 04-01 The Mendel- Singapore Science Park 1 118 225, Singapore

RÉSUMÉ

Higher Basidiomycota mushrooms arc unlimited sources of anticancer and immunostimulating polysaccharides. Many if not all Basidiomycota mushrooms contain biologically active polysaccharides. The data about mushrooms containing such polysaccharides are summarized. Six hundred and fifty-one species and 7 intraspecific taxa from 182 genera of higher Hetero- and Homobasidiomycetes contain pharmacologically active polysaccharides. Fruiting bodies, culture mycelium, and culture broth are sources of antitumor polysaccharides. The present review includes the data on the chemical structure of primary types of biologically active polysaccharides found in mushrooms. From 10 to 30 fractions of polysaccharides can be extracted from mushroom material, and most of them demonstrated antitumor activity. Special attention is turned to comparative analysis of polysaccharide fraction composition in fruiting bodies and culture mycelia of the same species. It is shown in examples of Agaricus blazei, Ganoderma tsugae, and Grifola frondosa that antitumor polysaccharides obtained from fruiting bodies, culture mycelia. or produced in a culture medium have a different chemical structure, and some polysaccharides developed in pure culture conditions were never found in fruiting bodies. Fractionation procedures for polysaccharide extraction and methods of their activation by chemical modification arc reviewed.


Articles with similar content:

Medicinal Mushroom Science: History, Current Status, Future Trends, and Unsolved Problems
International Journal of Medicinal Mushrooms, Vol.12, 2010, issue 1
Solomon P. Wasser
Therapeutic Effects of Substances Occurring in Higher Basidiomycetes Mushrooms: A Modern Perspective
Critical Reviews™ in Immunology, Vol.19, 1999, issue 1
Solomon P. Wasser, Alexander L. Weis
The Extraction and Development of Antitumor-Active Polysaccharides from Medicinal Mushrooms in Japan (Review)
International Journal of Medicinal Mushrooms, Vol.1, 1999, issue 1
Takashi Mizuno
Medicinal Properties of Substances Occurring in Higher Basidiomycetes Mushrooms: Current Perspectives (Review)
International Journal of Medicinal Mushrooms, Vol.1, 1999, issue 1
Solomon P. Wasser, Alexander L. Weis
Volatile Composition of Some Cultivated and Wild Culinary-Medicinal Mushrooms from Hungary
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 5
Andras Geosel, Maria Amtmann, Mariann Csóka, Kornel Korany