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International Journal of Medicinal Mushrooms

Publication de 12  numéros par an

ISSN Imprimer: 1521-9437

ISSN En ligne: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antioxidative and Inhibitory Effects of the Fruiting Body of Black Lingzhi Mushroom, Amauroderma rugosum (Agaricomycetes), on LDL Oxidation and HMG-CoA Reductase Activity

Volume 19, Numéro 9, 2017, pp. 797-807
DOI: 10.1615/IntJMedMushrooms.2017024374
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RÉSUMÉ

Amauroderma rugosum fruiting bodies possess excellent cardiovascular benefits, including antioxidative, antihyperlipidemic, antihypertensive, antiinflammatory, anti-platelet aggregation, and antithrombotic effects. In this article, we describe our investigations of the in vitro antioxidant activity and in vitro antiatherosclerotic potential through inhibitory effects on low-density lipoprotein (LDL), LDL peroxidation, and 3-hydroxy3-methylglutaryl-coenzyme A (HMG-CoA) reductase catalytic activity using various fruiting body extracts partitioned with an organic solvent. Among 5 extracts/fractions tested, the semipolar ethyl acetate (EA) fraction demonstrated good antioxidant capacity based on total phenolic content, 2,2-diphenyl-1-picrylhydrazyl free radical scavenging, ferrous ion-chelating ability, cupric ion-reducing antioxidant capacity, and lipid peroxidation assays. The EA fraction also showed the strongest inhibitory effect on Cu2+-induced LDL oxidation via thiobarbituric acid reactive substances formation and HMG-CoA reductase activity. Chemical analysis conjointly identified 10 phenolic compounds (4 benzoic acid derivatives, 3 flavonoids, 1 cinnamic acid, 1 hexahydroxydiphenic acid dilactone, and 1 xanthone derivative), some of which play pivotal roles in arresting the physiopathogenesis of atherosclerosis, thereby attenuating the risk of cardiovascular events occurring.

CITÉ PAR
  1. Félix Rafael, Valentão Patrícia, Andrade Paula B., Félix Carina, Novais Sara C., Lemos Marco F. L., Evaluating the In Vitro Potential of Natural Extracts to Protect Lipids from Oxidative Damage, Antioxidants, 9, 3, 2020. Crossref

  2. Lin Weiping, Shi Yanhua, Jia Guangtao, Sun Hengyi, Sun Tongyi, Hou Dianhai, Genome sequencing and annotation and phylogenomic analysis of the medicinal mushroom Amauroderma rugosum, a traditional medicinal species in the family Ganodermataceae, Mycologia, 113, 2, 2021. Crossref

  3. Li Jingjing, Cheng Yanfen, Li Renkai, Wu Xiaoping, Zheng Chengwen, Shiu Polly Ho-Ting, Chan Jacqueline Cho-Ki, Rangsinth Panthakarn, Liu Conghui, Leung Susan Wai-Sum, Lee Simon Ming-Yuen, Zhang Chen, Fu Chaomei, Zhang Jinming, Cheung Timothy Man-Yau, Leung George Pak-Heng, Liang Shao, Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways, Oxidative Medicine and Cellular Longevity, 2022, 2022. Crossref

  4. Mai Yanzhen, Xu Siyuan, Shen Ru, Feng Bairu, He Hong, Xu Yifei, Gastroprotective effects of water extract of domesticated Amauroderma rugosum against several gastric ulcer models in rats, Pharmaceutical Biology, 60, 1, 2022. Crossref

  5. Zheng Cheng‐Wen, Cheung Timothy Man‐Yau, Leung George Pak‐Heng, A review of the phytochemical and pharmacological properties of Amauroderma rugosum , The Kaohsiung Journal of Medical Sciences, 38, 6, 2022. Crossref

  6. Theofanous Thekla, Kourti Malamati, Abrogating Oxidative Stress as a Therapeutic Strategy Against Parkinson’s Disease: A Mini Review of the Recent Advances on Natural Therapeutic Antioxidant and Neuroprotective Agents, Medicinal Chemistry, 18, 7, 2022. Crossref

  7. Shiu Polly Ho-Ting, Li Jingjing, Zheng Chengwen, Rangsinth Panthakarn, Li Renkai, Cheung Queenie Tze-Lam, Lau Angel Heng-Yee, Chan Jacqueline Cho-Ki, Kwan Yiu-Wa, Cheung Timothy Man-Yau, Leung George Pak-Heng, Amauroderma rugosum Extract Suppresses Inflammatory Responses in Tumor Necrosis Factor Alpha/Interferon Gamma-Induced HaCaT Keratinocytes, Molecules, 27, 19, 2022. Crossref

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