Abonnement à la biblothèque: Guest
Portail numérique Bibliothèque numérique eBooks Revues Références et comptes rendus Collections
International Journal of Medicinal Mushrooms
Facteur d'impact: 1.423 Facteur d'impact sur 5 ans: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimer: 1521-9437
ISSN En ligne: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v18.i12.10
pages 1061-1069

Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps

Jasmina Ćilerdžić
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Mirjana Stajic
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Lada Živković
Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
Jelena Vukojević
Institute of Botany and Botanical Garden "Jevremovac", Faculty of Biology, University of Belgrade, Takovska 43, 11000 Belgrade, Serbia
Vladan Bajic
Laboratory for Radiology and Molecular Genetics, Institute for Nuclear Sciences "Vinca," University of Belgrade, Belgrade, Serbia
Biljana Spremo-Potparević
Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia

RÉSUMÉ

Ganoderma lucidum is traditionally used in Eastern medicine to preserve vitality, promote longevity, and treat disease. It possesses immunomodulatory, antitumor, antimicrobial, and antiaging activities, among others, but one of the most important is its antioxidant property, which is the basis for other effects, because free radicals trigger many diseases. The substrate commonly used for commercial cultivation of G. lucidum is not environmentally friendly nor economically justified, so there is a need to find new alternative substrates. The aim of this study was to analyze the effect of substrate composition on the bioactivity of G. lucidum basidiocarps. G. lucidum was cultivated on 2 different substrates: (1) a mixture of wheat straw, grapevine branches, and wheat bran, and (2) wheat straw. Commercial fruiting bodies, cultivated on oak sawdust, were used as the control. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging ability, total phenols, and flavonoid content were determined spectrophotometrically to define the antioxidative potential of basidiocarp extracts. The comet test was performed to detect the degree of DNA damage in the cells that were exposed to G. lucidum extracts before and after the effect of oxidants. Higher antioxidative potential was observed for the extract of G. lucidum basidiocarps cultivated on wheat straw compared with that from the mixed substrate and especially with commercial ones. The alternatively cultivated basidiocarps also showed stronger antigenotoxic potential compared with commercial ones. The study showed that fruiting bodies produced on wheat straw, one of the most accessible and cheapest crop residues, are more potent antioxidant and antigenotoxic agents than commercially cultivated ones.


Articles with similar content:

Plasma-based Stimulation of Biotechnological Processes in Ganoderma lucidum Mycelia as Example for a Eukaryotic Organism
Plasma Medicine, Vol.4, 2014, issue 1-4
Christian Backer, Martina Wurster, Christian Schulze, Ulrike Lindequist, Thomas von Woedtke, Anja Funke, Beate Haertel
Species of Genus Ganoderma (Agaricomycetes) Fermentation Broth: A Novel Antioxidant and Antimicrobial Agent
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 5
Mirjana Stajić, Jelena Vukojević, Marijana Kosanic, Jasmina Ćilerdžić, Branislav Ranković
Partial Purification and Antioxidant Activities of Oligosaccharides from Hericium caput-medusae (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 10
Hui Song , Yue Miao , Dong Zhen , Shad Mahfuz , Guihong Ren, Fei Zhao
A Comparative Study of the Antimicrobial, Antioxidant, and Cytotoxic Activities of Methanol Extracts from Fruit Bodies and Fermented Mycelia of Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes)
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 5
Tao Yang, Caihong Dong, Tiantian Lian
Comparison of Antioxidant and Antiproliferation Activities of Polysaccharides from Eight Species of Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 3
Yangyang Yong, Yifan Gu, Zeliang Wang, Shizhu Zhang, Peiying Chen, Ling Lu