RT Journal Article ID 0df6fa612762ffb5 A1 Zeng, Jie A1 Xie, Longxiang A1 Luo, Hongping A1 Xie, Jianping T1 The Epigenetic Modifications of Genes Associated with Tuberculosis Susceptibility and Implications for Epi-Drugs JF Critical Reviews™ in Eukaryotic Gene Expression JO CRE YR 2015 FD 2015-11-10 VO 25 IS 4 SP 349 OP 362 K1 tuberculosis K1 epigenetic K1 susceptibility AB Epigenetics of genes associated with tuberculosis susceptibility such as DNA methylation, posttranslational histone modifications, and non-coding RNA remain largely untapped field for better tuberculosis control. Many genes involved in tuberculosis susceptibility (e.g., NRAMP1 (SLC11A1), IFNG, NOS2A, VDR, ISG15, TACO, TLR1, TLR, IL18R1, chemokines, PADI, DUSP14, MBL, and MASP-2) have been subjected to epigenetic modification. Our summary of these modifications provides fresh insights into the pathogenesis of tuberculosis and inspires targets discovery for host-derived therapy. PB Begell House LK https://www.dl.begellhouse.com/journals/6dbf508d3b17c437,54a2f639520818b3,0df6fa612762ffb5.html