RT Journal Article ID 298cc3f427506118 A1 Merdivan, Simon A1 Willke, Christoph A1 Lindequist, Ulrike T1 Development and Validation of an LC-MS/MS Method for the Quantification of Agaritine in Mushrooms JF International Journal of Medicinal Mushrooms JO IJM YR 2016 FD 2016-03-09 VO 18 IS 1 SP 13 OP 21 K1 medicinal mushrooms K1 agaritine K1 LC-MS/MS K1 Agaricus brasiliensis K1 Agaricus bisporus AB Agaritine, an aromatic hydrazine, is found as a secondary metabolite in mushroom species. It is among others suspected to exhibit genotoxic activity. This publication describes the validation of a method for the quantification of agaritine in mushrooms (i.e., extraction and purification by solid phase extraction) and measurement by liquid chromatography with tandem mass spectrometry detection in positive ionization mode. The results show this method to be selective, accurate, and precise. This method could be used for the quality control of pharmaceutical preparations containing mushrooms. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,33df00905b660ea5,298cc3f427506118.html