%0 Journal Article
%A Schutzer, Steven E.
%A Coyle, P. K.
%D 2016
%I Begell House
%K Borrelia, Lyme disease , immune complexes
%N 3-4
%P 213-224
%R 10.1615/ForumImmunDisTher.2017019621
%T Immune Complex Analysis in Active Lyme Disease
%U https://www.dl.begellhouse.com/journals/2c6306423483e001,6deddb8911c6adff,583be4ad20451fd6.html
%V 7
%X Lyme disease (LD) is a growing infectious disease. Assays that can detect active infection early are needed to allow appropriate antibiotic therapy to begin when there is the best chance for a cure. The most frequently used assays are those based on antibodies to Borrelia burgdorferi or its variants, the causative agent of LD. However, an antibody test at a single time point only measures exposure, not necessarily an active infection. In contrast,
antibodies that are bound to a target antigen in a circulating immune complex form do indicate active infection. Here, we present data supporting the use of such assays in LD.
%8 2017-10-11