RT Journal Article ID 583be4ad20451fd6 A1 Schutzer, Steven E. A1 Coyle, P. K. T1 Immune Complex Analysis in Active Lyme Disease JF Onco Therapeutics JO OT YR 2016 FD 2017-10-11 VO 7 IS 3-4 SP 213 OP 224 K1 Borrelia K1 Lyme disease K1 immune complexes AB Lyme disease (LD) is a growing infectious disease. Assays that can detect active infection early are needed to allow appropriate antibiotic therapy to begin when there is the best chance for a cure. The most frequently used assays are those based on antibodies to Borrelia burgdorferi or its variants, the causative agent of LD. However, an antibody test at a single time point only measures exposure, not necessarily an active infection. In contrast, antibodies that are bound to a target antigen in a circulating immune complex form do indicate active infection. Here, we present data supporting the use of such assays in LD. PB Begell House LK https://www.dl.begellhouse.com/journals/2c6306423483e001,6deddb8911c6adff,583be4ad20451fd6.html