RT Journal Article
ID 7120028944657568
A1 Timchenko, Victoria
A1 Dombrovsky, Leonid A. 
T1 LASER INDUCED HYPERTHERMIA OF SUPERFICIAL TUMORS: A TRANSIENT THERMAL MODEL FOR INDIRECT HEATING STRATEGY
JF Computational Thermal Sciences: An International Journal
JO CTS
YR 2012
FD 2012-12-10
VO 4
IS 6
SP 457
OP 475
K1 hyperthermia
K1 superficial tumors
K1 radiative transfer
K1 transient heat transfer in human body
AB An indirect heating strategy based on laser irradiation of surrounding tissues as an alternative to a direct irradiation of superficial tumors is presented in this paper. The computational analysis is based on two-dimensional axisymmetric models for both radiative transfer and transient heat transfer in a human body Coupled transient energy equations for composite human tissue take into account the metabolic heat generation and heat conduction, blood perfusion through capillaries, the volumetric heat transfer between arterial blood and ambient tissue, the periodic laser heating, and also heat transfer between the human body and ambient medium. The relative role of the treatment parameters on the transient temperature field and degree of thermal conversions in human tissues has been studied by solving an example problem for a superficial human cancer with and without embedded gold nanoshells. The thermal conversions in blood and tumor tissue as a response to hyperthermia are estimated by solving Arrhenius-type kinetic equations. It is shown that required parameters for hyperthermia treatment can be attained without gold nanoshells.
PB Begell House
LK https://www.dl.begellhouse.com/journals/648192910890cd0e,5601d1006842027b,7120028944657568.html