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Journal of Long-Term Effects of Medical Implants
SJR: 0.332 SNIP: 0.491 CiteScore™: 0.89

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v19.i3.40
pages 195-199

Standard Operating Procedures: The Devil Is in the Details

Simrit Bains
Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
Mohit Bhandari
CLARITY Research Group, McMaster University, Department of Orthopedic Surgery Musculoskeletal Research Unit, Canada and Division of Orthopaedic Surgery and Department of Clinical Epidemiology & Biostatistics, Hamilton General Hospital, Canada
Beate Hanson
AO Foundation, AO Clinical Investigation and Documentation (AOCID), Dübendorf, Switzerland


Standard operating procedures (SOPs) play an important role in clinical research due to their role in promoting good clinical practice. Due to their importance, it will be explored in this article how and why this is the case, in addition to examining the value of SOPs in conducting an effective clinical trial. This will be done by first introducing the concept of SOPs, which is followed by a discussion of their advantages and how to best develop and use them.