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Journal of Long-Term Effects of Medical Implants

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v16.i4.30
pages 291-300

Long-Term Follow-Up Study of Bioactive Bone Cement in Canine Total Hip Arthroplasty

Bojian Liang
Department of Orthopaedic Surgery, Kyoto University, Japan
Shunsuke Fujibayashi
Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin-kawahara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan
Hiroshi Fujita
Department of Orthopaedic Surgery, Kyoto University, Japan
Kentaro Ise
Department of Orthopaedic Surgery, Kyoto University, Japan
Masashi Neo
Department of Orthopaedic Surgery, Kyoto University, Japan
Takashi Nakamura
Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin-kawahara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan

ABSTRACT

We report a long-term study of bioactive bone cement (BABC) in a canine total hip arthroplasty (THA) at follow-up of 8 years. Previous studies have shown excellent biomechanical and histological results at follow-up of 6, 12, and 24 months. In the present study, THA was performed in a beagle dog using BABC consisting of an apatite- and wollastonite-containing glass ceramic (AW-GC) powder and SiO2 powder as the filler and a bisphenol-a-glycidyl methacrylate (Bis-GMA) based resin as the organic matrix. Histological examination showed direct bonding between BABC and bone without any intervening soft tissue layer at the BABC-bone interface. A reactive layer, through which BABC bonded to the bone, was observed thicker at 8 years than it was at 24 weeks. No adverse effects of BABC were observed. BABC maintained the high bioactivity and direct bonding to bone in a canine THA at follow-up of 8 years.