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Journal of Long-Term Effects of Medical Implants

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v12.i2.80
6 pages

Skin Wound Healing and Cell-Mediated DNA Transport

William C. Lineaweaver
Division of Plastic Surgery. The University of Mississippi Medical Center, 2500, North State Street, Jackson, MS 39216-4505
Barbara Rogers
Coordinator, Nursing Research; Division of Plastic Surgery, University of Mississippi Medical Center, Jackson, MS 39216

ABSTRACT

Since the discovery of epidermal growth factor (EGF) in 1972, a major emphasis in the study of wound healing has been the role of growth factors and cytokines, and identification and characterization of growth factors and cytokines and their use as therapeutic agents has been a major area of clinical and basic research. This article presents an overview of the process of wound healing of the skin and perspectives on how gene therapy and DNA technology may be used to improve treatment of wounds.