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Journal of Long-Term Effects of Medical Implants
SJR: 0.332 SNIP: 0.491 CiteScore™: 0.89

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v17.i2.40
pages 111-120

User's Guide to a Randomized Trial about an Orthopaedic Implant

Dan Vena
Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada
Eric Morrison
Department of Clinical Epidemiology & Biostatistics,McMaster University, Hamilton, Ontario, Canada
Anders Joensson
Osteosynthesis and Trauma Care Foun¬dation, Nice, France
Mohit Bhandari
CLARITY Research Group, McMaster University, Department of Orthopedic Surgery Musculoskeletal Research Unit, Canada and Division of Orthopaedic Surgery and Department of Clinical Epidemiology & Biostatistics, Hamilton General Hospital, Canada


Evidence-based orthopaedic surgery emphasizes the need to properly appraise the available literature to evaluate the efficacy of therapeutic interventions before accepting them into daily practice. A properly designed and well-conducted randomized controlled trial provides a very high level of evidence on which to guide clinical decisions in orthopaedic surgery. The purpose of this article is to assist orthopaedic surgeons with this process, focusing on critically reviewing randomized controlled trials.