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Journal of Long-Term Effects of Medical Implants

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.2015011782
pages 289-295

Side Effects of Radiation in Bone and Cartilage: An FT-IR Analysis

Andreas F. Mavrogenis
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
Panayiotis D. Megaloikonomos
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
Georgios N. Panagopoulos
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
Panayiotis J. Papagelopoulos
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
Theofilos Theophanides
National Technical University of Athens, Radiation Chemistry & Biospectroscopy, Athens, Greece
Jane Anastassopoulou
National Technical University of Athens, Radiation Chemistry & Biospectroscopy, Athens, Greece

ABSTRACT

Although radiation therapy is an essential treatment of cancers, it is associated with unwanted complications. The purpose of this review is to summarize the current knowledge regarding the side effects of radiation in bone and articular cartilage and to recommend Fourier transform infrared spectroscopy to monitor the differences in infrared spectra between healthy and irradiated bone and cartilage.