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Journal of Long-Term Effects of Medical Implants

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v13.i5.40
10 pages

Experience Improves Successful Use of Fibrin Sealant in Total Knee Arthroplasty: Implications for Surgical Education

Gwo-Jaw Wang
Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA
Charles A. Goldthwaite, Jr.
Surgical Therapeutic Advancement Center, University of Virginia, Charlottesville, Virginia, USA
Sandra G. Burks
Surgical Therapeutic Advancement Center, University of Virginia, Charlottesville, Virginia, USA
William D. Spotnitz
Division of Thoracic and Cardiovascular Surgery, University of Florida; Surgical Therapeutic Advancement Center, University of Virginia, Charlottesville, Virginia, USA

ABSTRACT

This study evaluating fibrin sealant application in total knee arthroplasty (TKA) found significant differences in the decline in adjusted hemoglobin loss at 48 hours postoperatively in the treatment group (FS) relative to the control group (C) when the groups were segregated into early and late subgroups. The decline between the late C, 3.53 ± 0.22 g/dL, and the late FS, 3.01 ± 0.20 g/dL, was 0.52 g/dL (p = 0.04). The decline between the early C, 3.51 ± 0.21 g/dL, and the early FS, 3.25 ± 0.22 g/dL, was 0.26 g/dL (p = 0.34). This study demonstrates the importance of experience and education in successful application of tissue adhesives.