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Journal of Long-Term Effects of Medical Implants
SJR: 0.332 SNIP: 0.491 CiteScore™: 0.89

ISSN Print: 1050-6934
ISSN Online: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.v21.i2.40
pages 139-148

Bioactive Glass S53P4 and Autograft Bone in Treatment of Depressed Tibial Plateau Fractures - A Prospective Randomized 11-year Follow-Up

K . Pernaa
Department of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland
I. Koski
Medical Imaging Center of Southwest Finland, Turku University Hospital and University of Turku, Turku, Finland
K. Mattila
Medical Imaging Center of Southwest Finland, Turku University Hospital and University of Turku, Turku, Finland
E. Gullichsen
Department of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland
J. Heikkila
Department of Orthopedic and Traumatology, The Biomaterial Project of Turku, Turku University Hospital, Turku, Finland
A. J. Aho
Department of Orthopedic and Traumatology, The Biomaterial Project of Turku, Turku University Hospital, Turku, Finland
Nina Lindfors
Helsnki University Central Hospital

ABSTRACT

The clinical and radiological outcomes of bioactive glass (BAG)-S53P4 and autograft bone (AB) used as bone-graft substitutes in depressed tibial plateau fractures were evaluated in a prospective randomized 11-year follow-up study. All patients (n = 29) had sustained tibial plateau fractures with a joint-line depression of >3 mm. Fifteen patients (5 patients the BAG group, 10 patients in the AB group) participated in this long-term follow-up. X-rays were taken preoperatively, postoperatively, and at the long-term follow-up, and computed tomography (CT) scans were made at the long-term follow-up for evaluation of the bone substitute, osteoarthritis, the tibial-femoral angle, and deviation of mechanical axes. No material-dependent adverse effects were seen in any patient. The means of the articular surface depression on X-rays at the long-term follow-up were 1.4 mm (range: 0−2 mm) in the BAG group and 1.4 mm (range: 0−4 mm) in the AB group, and on CT scans the means were 2.2 mm (range: 2−3 mm), and 2.1 mm (range: 0−3), respectively. No significant difference in the tibial-femoral angle or deviation of mechanical axes was observed between the two groups. BAG-S53P4 can be used as a bone substitute in depressed lateral tibial plateau fractures with good functional and radiological long-term results.