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Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Chemokines in Respiratory Viral Infections: Focus on Their Diagnostic and Therapeutic Potential

Volume 31, Issue 4, 2011, pp. 341-356
DOI: 10.1615/CritRevImmunol.v31.i4.40
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ABSTRACT

Chemokines are small chemoattractant cytokines involved in cell trafficking and activation. Despite the general nonspecific nature of chemokine activity in certain instances, specific chemokine expression patterns have been associated with specific disease states. In the field of respiratory viral infection, evidence suggests that response to viral invasion is regulated by a distinct chemokine expression profile involving more CC chemokines than CXC chemokines. Moreover, among the CC chemokines, CCL3 and CCL5 appear to be most commonly implicated in viral respiratory disease. Most data available in this field have been derived from in vitro studies, as well as studies conducted in animal models with limited evidence obtained in settings of actual human disease. In the present review, we focus on the diagnostic, prognostic, and therapeutic potential of virus-induced chemokine activity as reflected by studies conducted in actual disease states, either in animal models or humans. We further discuss whether these data advocate chemokines as a realistic clinical tool for the management of viral infection.

CITED BY
  1. Zlotnik Albert, Yoshie Osamu, The Chemokine Superfamily Revisited, Immunity, 36, 5, 2012. Crossref

  2. Suryadevara Manika, Bonville Cynthia A, Rosenberg Helene F, Domachowske Joseph B, Local production of CCL3, CCL11, and IFN-γ correlates with disease severity in murine parainfluenza virus infection, Virology Journal, 10, 1, 2013. Crossref

  3. Christiaansen Allison, Varga Steven M, Spencer Juliet V, Viral manipulation of the host immune response, Current Opinion in Immunology, 36, 2015. Crossref

  4. Luo Chang, Liu Jianxin, Qi Wenbao, Ren Xujiao, Lu Rong, Liao Ming, Ning Zhangyong, Dynamic analysis of expression of chemokine and cytokine gene responses to H5N1 and H9N2 avian influenza viruses in DF-1 cells, Microbiology and Immunology, 62, 5, 2018. Crossref

  5. Rodriguez Carlos, African or African American? That is the question. The Duffy antigen and the Chemokine Storm in Covid-19, Qeios, 2020. Crossref

  6. Rodriguez Carlos, African or African American? That is the question. The Duffy antigen and the Chemokine Storm in Covid-19, Qeios, 2020. Crossref

  7. Williams Andrew, Chemokines: CC Family, in Encyclopedia of Respiratory Medicine, 2022. Crossref

  8. Su Aru, Guo Yujie, Tian Huihui, Zhou Yanting, Li Wenting, Tian Yadong, Li Kui, Sun Guirong, Jiang Ruirui, Yan Fengbin, Kang Xiangtao, Analysis of miRNA and mRNA reveals core interaction networks and pathways of dexamethasone-induced immunosuppression in chicken bursa of Fabricius, Molecular Immunology, 134, 2021. Crossref

  9. León Alberto J., Banner David, Xu Luoling, Ran Longsi, Peng Zhiyu, Yi Kang, Chen Chao, Xu Fengping, Huang Jinrong, Zhao Zhen, Lin Zhen, Huang Stephen H. S., Fang Yuan, Kelvin Alyson A., Ross Ted M., Farooqui Amber, Kelvin David J., Sequencing, Annotation, and Characterization of the Influenza Ferret Infectome, Journal of Virology, 87, 4, 2013. Crossref

  10. Cruz Jazmina L. G., Becares Martina, Sola Isabel, Oliveros Juan Carlos, Enjuanes Luis, Zúñiga Sonia, Alphacoronavirus Protein 7 Modulates Host Innate Immune Response, Journal of Virology, 87, 17, 2013. Crossref

  11. Li Jiao, Xue Ling, Wang Jiachao, Meng Aihong, Qiao Jiajun, Li Miao, Wang Xiuli, Meng Lingtong, Ning Jingyuan, Gao Xue, Li Wenjian, Ma Cuiqing, Wei Lin, Williams Bryan R. G., Activation of the Chemokine Receptor CCR1 and Preferential Recruitment of Gαi Suppress RSV Replication: Implications for Developing Novel Respiratory Syncytial Virus Treatment Strategies, Journal of Virology, 96, 22, 2022. Crossref

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