Library Subscription: Guest
Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

NK Cells and Their Ability to Modulate T Cells during Virus Infections

Volume 34, Issue 5, 2014, pp. 359-388
DOI: 10.1615/CritRevImmunol.2014010604
Get accessGet access

ABSTRACT

Natural killer (NK) cells are important in protection against virus infections, and many viruses have evolved mechanisms to thwart NK cell activity. NK cells respond to inflammatory signals at an early stage of virus infection, resulting in proliferation, cytokine production, and cytolytic activity that can reduce virus loads. Moreover, the rapid kinetics of the NK cell response enables NK cells to influence other populations of innate immune cells, affect the inflammatory milieu, and guide adaptive immune responses to infection. Early NK cell interactions with other leukocytes can have long-lasting effects on the number and quality of memory T cells, as well as impact the exhaustion of T cells during chronic infections. The ability of NK cells to modulate T cell responses can be mediated through direct T-NK interactions, cytokine production, or indirectly through dendritic cells and other cell types. Herein, we summarize our current understanding of how NK cells interact with T cells, dendritic cells, B cells, and other cell types involved in adaptive immune responses to virus infection. We outline several mechanisms by which NK cells enhance or suppress adaptive immune response and long-lived immunological memory.

CITED BY
  1. Liu Lisa L., Pfefferle Aline, Yi Sheng Vincent Oei, Björklund Andreas T., Béziat Vivien, Goodridge Jodie P., Malmberg Karl-Johan, Harnessing adaptive natural killer cells in cancer immunotherapy, Molecular Oncology, 9, 10, 2015. Crossref

  2. Vargas-Inchaustegui Diego A., Ying Olivia, Demberg Thorsten, Robert-Guroff Marjorie, Evaluation of Functional NK Cell Responses in Vaccinated and SIV-Infected Rhesus Macaques, Frontiers in Immunology, 7, 2016. Crossref

  3. Lam Viola C, Lanier Lewis L, NK cells in host responses to viral infections, Current Opinion in Immunology, 44, 2017. Crossref

  4. Becherucci V., Allegro E., Brugnolo F., Piccini L., Gori V., Bisin S., Bindi B., Ceccantini R., Pavan P., Cunial V., Gentile F., Ermini S., Bambi F., Extracorporeal photopheresis as an immunomodulatory agent: Haematocrit-dependent effects on natural killer cells, Journal of Clinical Apheresis, 32, 4, 2017. Crossref

  5. Littwitz-Salomon Elisabeth, Dittmer Ulf, Sutter Kathrin, Insufficient natural killer cell responses against retroviruses: how to improve NK cell killing of retrovirus-infected cells, Retrovirology, 13, 1, 2016. Crossref

  6. Kawahara Mamoru, Hasegawa Nozomi, Takaku Hiroshi, Rawkins Ann, Murine Splenic Natural Killer Cells Do Not Develop Immunological Memory after Re-Encounter with Mycobacterium bovis BCG, PLOS ONE, 11, 3, 2016. Crossref

  7. Miletic Antonija, Lenartic Maja, Popovic Branka, Brizic Ilija, Trsan Tihana, Miklic Karmela, Mandelboim Ofer, Krmpotic Astrid, Jonjic Stipan, NCR1-deficiency diminishes the generation of protective murine cytomegalovirus antibodies by limiting follicular helper T-cell maturation, European Journal of Immunology, 47, 9, 2017. Crossref

  8. Teoh Jeffrey J., Gamache Awndre E., Gillespie Alyssa L., Stadnisky Michael D., Yagita Hideo, Bullock Timothy N. J., Brown Michael G., Acute Virus Control Mediated by Licensed NK Cells Sets Primary CD8+ T Cell Dependence on CD27 Costimulation, The Journal of Immunology, 197, 11, 2016. Crossref

  9. Semeraro Michele L., Glenn Lindsey M., Morris Margaret A., The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes Progression, Frontiers in Endocrinology, 8, 2017. Crossref

  10. Marciano Beatriz E., Holland Steven M., Primary Immunodeficiency Diseases: Current and Emerging Therapeutics, Frontiers in Immunology, 8, 2017. Crossref

  11. Ptaschinski Catherine, Lukacs Nicholas W., Acute and Chronic Inflammation Induces Disease Pathogenesis, in Molecular Pathology, 2018. Crossref

  12. Bayer Allison L., Fraker Christopher A., The Folate Cycle As a Cause of Natural Killer Cell Dysfunction and Viral Etiology in Type 1 Diabetes, Frontiers in Endocrinology, 8, 2017. Crossref

  13. Wang Li, Crosstalk between innate and adaptive immunity in hepatitis B virus infection, World Journal of Hepatology, 7, 30, 2015. Crossref

  14. Abel Alex M., Yang Chao, Thakar Monica S., Malarkannan Subramaniam, Natural Killer Cells: Development, Maturation, and Clinical Utilization, Frontiers in Immunology, 9, 2018. Crossref

  15. Wagstaffe Helen R, Mooney Jason P, Riley Eleanor M, Goodier Martin R, Vaccinating for natural killer cell effector functions, Clinical & Translational Immunology, 7, 1, 2018. Crossref

  16. Mathew Anuja, Regulation and Function of NK and T Cells During Dengue Virus Infection and Vaccination, in Dengue and Zika: Control and Antiviral Treatment Strategies, 1062, 2018. Crossref

  17. Obaid Ayesha, Naz Anam, Ashraf Shifa Tariq, Awan Faryal Mehwish, Ikram Aqsa, Saeed Muhammad Tariq, Raza Abida, Ahmad Jamil, Ali Amjad, Formal Modeling of the Key Determinants of Hepatitis C Virus (HCV) Induced Adaptive Immune Response Network: An Integrative Approach to Map the Cellular and Cytokine-Mediated Host Immune Regulations, in Computational Science and Its Applications – ICCSA 2018, 10963, 2018. Crossref

  18. Hughes Heather K., Mills Ko Emily, Rose Destanie, Ashwood Paul, Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders, Frontiers in Cellular Neuroscience, 12, 2018. Crossref

  19. Neuss Sebastian, Bartel Yvonne, Born Christina, Weil Sandra, Koch Joachim, Behrends Christian, Hoffmeister Meike, Steinle Alexander, Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80, The Journal of Immunology, 201, 4, 2018. Crossref

  20. Borst Jannie, Ahrends Tomasz, Bąbała Nikolina, Melief Cornelis J. M., Kastenmüller Wolfgang, CD4+ T cell help in cancer immunology and immunotherapy, Nature Reviews Immunology, 18, 10, 2018. Crossref

  21. Khlifi Rihab, Dhaouefi Zaineb, Maatouk Mouna, Sassi Aicha, Boudhiba Najet, Ioannou Irina, Ghedira Kamel, Chekir-Ghedira Leila, Kilani-Jaziri Soumaya, Heat treatment improves the immunomodulatory and cellular antioxidant behavior of a natural flavanone: Eriodictyol, International Immunopharmacology, 61, 2018. Crossref

  22. Hiršl Lea, Brizić Ilija, Jenuš Tina, Juranić Lisnić Vanda, Reichel Johanna Julia, Jurković Slaven, Krmpotić Astrid, Jonjić Stipan, Murine CMV Expressing the High Affinity NKG2D Ligand MULT-1: A Model for the Development of Cytomegalovirus-Based Vaccines, Frontiers in Immunology, 9, 2018. Crossref

  23. Fisicaro Paola, Rossi Marzia, Vecchi Andrea, Acerbi Greta, Barili Valeria, Laccabue Diletta, Montali Ilaria, Zecca Alessandra, Penna Amalia, Missale Gabriele, Ferrari Carlo, Boni Carolina, The Good and the Bad of Natural Killer Cells in Virus Control: Perspective for Anti-HBV Therapy, International Journal of Molecular Sciences, 20, 20, 2019. Crossref

  24. Obaid Ayesha, Naz Anam, Ikram Aqsa, Awan Faryal Mehwish, Raza Abida, Ahmad Jamil, Ali Amjad, Model of the adaptive immune response system against HCV infection reveals potential immunomodulatory agents for combination therapy, Scientific Reports, 8, 1, 2018. Crossref

  25. Gyurova Ivayla E., Schlums Heinrich, Sucharew Heidi, Ambroggio Lilliam, Ochayon David E., Win Hannah Than, Bryceson Yenan T., Bernstein David I., Waggoner Stephen N., Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection, Frontiers in Immunology, 10, 2019. Crossref

  26. Ferrari Carlo, Barili Valeria, Varchetta Stefania, Mondelli Mario U., Immune Mechanisms of Viral Clearance and Disease Pathogenesis During Viral Hepatitis, in The Liver, 2020. Crossref

  27. Wang Hong, Li Jing, Dong Xiaojing, Zhou Xaoqing, Zhao Lei, Wang Xiao, Rashu Rasheduzzaman, Zhao Weiming, Yang Xi, NK Cells Contribute to Protective Memory T Cell Mediated Immunity to Chlamydia muridarum Infection, Frontiers in Cellular and Infection Microbiology, 10, 2020. Crossref

  28. Erokhina Sofya A., Streltsova Maria A., Kanevskiy Leonid M., Grechikhina Maria V., Sapozhnikov Alexander M., Kovalenko Elena I., HLA‐DR‐expressing NK cells: Effective killers suspected for antigen presentation, Journal of Leukocyte Biology, 109, 2, 2021. Crossref

  29. Niehrs Annika, Altfeld Marcus, Regulation of NK-Cell Function by HLA Class II, Frontiers in Cellular and Infection Microbiology, 10, 2020. Crossref

  30. Kumar V, Innate lymphoid cell and adaptive immune cell cross‐talk: A talk meant not to forget, Journal of Leukocyte Biology, 108, 1, 2020. Crossref

  31. Sotgiu Stefano, Manca Salvatorica, Gagliano Antonella, Minutolo Alessandra, Melis Maria Clotilde, Pisuttu Giulia, Scoppola Chiara, Bolognesi Elisabetta, Clerici Mario, Guerini Franca Rosa, Carta Alessandra, Immune regulation of neurodevelopment at the mother–foetus interface: the case of autism, Clinical & Translational Immunology, 9, 11, 2020. Crossref

  32. Riese Peggy, Trittel Stephanie, Pathirana Rishi D., Klawonn Frank, Cox Rebecca J., Guzmán Carlos A., Responsiveness to Influenza Vaccination Correlates with NKG2C-Expression on NK Cells, Vaccines, 8, 2, 2020. Crossref

  33. Pontrelli Paola, Rascio Federica, Castellano Giuseppe, Grandaliano Giuseppe, Gesualdo Loreto, Stallone Giovanni, The Role of Natural Killer Cells in the Immune Response in Kidney Transplantation, Frontiers in Immunology, 11, 2020. Crossref

  34. Huot Nicolas, Rascle Philippe, Petitdemange Caroline, Contreras Vanessa, Palgen Jean-Louis, Stahl-Hennig Christiane, Le Grand Roger, Beignon Anne-Sophie, Jacquelin Beatrice, Müller-Trutwin Michaela, Non-human Primate Determinants of Natural Killer Cells in Tissues at Steady-State and During Simian Immunodeficiency Virus Infection, Frontiers in Immunology, 11, 2020. Crossref

  35. Kucuksezer Umut Can, Aktas Cetin Esin, Esen Fehim, Tahrali Ilhan, Akdeniz Nilgun, Gelmez Metin Yusuf, Deniz Gunnur, The Role of Natural Killer Cells in Autoimmune Diseases, Frontiers in Immunology, 12, 2021. Crossref

  36. Bergantini Laura, d'Alessandro Miriana, Cameli Paolo, Cavallaro Dalila, Gangi Sara, Cekorja Behar, Sestini Piersante, Bargagli Elena, NK and T Cell Immunological Signatures in Hospitalized Patients with COVID-19, Cells, 10, 11, 2021. Crossref

  37. Kust Sofya A., Streltsova Maria A., Panteleev Alexander V., Karpina Natalya L., Lyadova Irina V., Sapozhnikov Alexander M., Kovalenko Elena I., HLA-DR-Positive NK Cells Expand in Response to Mycobacterium Tuberculosis Antigens and Mediate Mycobacteria-Induced T Cell Activation, Frontiers in Immunology, 12, 2021. Crossref

  38. Jegatheeswaran Sinthuja, Mathews Jessica A., Crome Sarah Q., Searching for the Elusive Regulatory Innate Lymphoid Cell, The Journal of Immunology, 207, 8, 2021. Crossref

  39. Palacios-Pedrero Miguel Ángel, Osterhaus Albert D. M. E., Becker Tanja, Elbahesh Husni, Rimmelzwaan Guus F., Saletti Giulietta, Aging and Options to Halt Declining Immunity to Virus Infections, Frontiers in Immunology, 12, 2021. Crossref

  40. Webb Tonya J., Inclusion criteria: how NK cells gain access to T cells, Journal of Clinical Investigation, 131, 18, 2021. Crossref

  41. Li Kangli, Wang Congcong, Yang Fan, Cao Weijun, Zhu Zixiang, Zheng Haixue, Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection, Frontiers in Immunology, 12, 2021. Crossref

  42. Rose David L., Reagin Katie L., Oliva Kimberly E., Tompkins S. Mark, Klonowski Kimberly D., Enhanced generation of influenza-specific tissue resident memory CD8 T cells in NK-depleted mice, Scientific Reports, 11, 1, 2021. Crossref

  43. Choudhury Sk Mohiuddin, Ma XuSheng, Dang Wen, Li YuanYuan, Zheng HaiXue, Recent Development of Ruminant Vaccine Against Viral Diseases, Frontiers in Veterinary Science, 8, 2021. Crossref

  44. Singh Rajeshwari, Goel Sumeet, Bourgeade Pascale, Aleya Lotfi, Tewari Devesh, Ayurveda Rasayana as antivirals and immunomodulators: potential applications in COVID-19, Environmental Science and Pollution Research, 28, 40, 2021. Crossref

  45. Bhagyaraj Ella, Wang Hongbin, Yang Xinghong, Hoffman Carol, Akgul Ali, Goodwin Zakia I., Pascual David W., Mucosal Vaccination Primes NK Cell-Dependent Development of CD8+ T Cells Against Pulmonary Brucella Infection, Frontiers in Immunology, 12, 2021. Crossref

  46. Yuan Wei, Huang Da, Wu Di, Chen Yuying, Ma Ke, Han Meifang, Luo Xiaoping, Yan Weiming, Ning Qin, Pegylated Interferon-ɑ (IFN-ɑ) Enhances the Inhibitory Effect of Natural Killer Cells on Regulatory T Cells via IFN-γ in Chronic Hepatitis B, The Journal of Infectious Diseases, 224, 11, 2021. Crossref

  47. Bezirganoglu Handan, Okur Nilufer, SARS‐CoV ‐2 associated with death in an infant with congenital chylothorax , Journal of Paediatrics and Child Health, 58, 3, 2022. Crossref

  48. Diniz Mariana O., Schurich Anna, Chinnakannan Senthil K., Duriez Marion, Stegmann Kerstin A., Davies Jessica, Kucykowicz Stephanie, Suveizdyte Kornelija, Amin Oliver E., Alcock Frances, Cargill Tamsin, Barnes Eleanor, Maini Mala K., NK cells limit therapeutic vaccine–induced CD8 + T cell immunity in a PD-L1–dependent manner , Science Translational Medicine, 14, 640, 2022. Crossref

  49. Gramegna Andrea, Lombardi Andrea, Lorè Nicola I., Amati Francesco, Barone Ivan, Azzarà Cecilia, Cirillo Daniela, Aliberti Stefano, Gori Andrea, Blasi Francesco, Innate and Adaptive Lymphocytes in Non-Tuberculous Mycobacteria Lung Disease: A Review, Frontiers in Immunology, 13, 2022. Crossref

  50. Littwitz-Salomon Elisabeth, Schimmer Simone, Dittmer Ulf, Kirchhoff Frank, Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses, Journal of Virology, 91, 22, 2017. Crossref

  51. Klomp Mitchell, Ghosh Sumit, Mohammed Sohail, Nadeem Khan M., From virus to inflammation, how influenza promotes lung damage, Journal of Leukocyte Biology, 110, 1, 2021. Crossref

  52. Wang Xiaorui, Bai Han, Ma Junpeng, Qin Hongyu, Zeng Qiqi, Hu Fang, Jiang Tingting, Mao Weikang, Zhao Yang, Chen Xiaobei, Qi Xin, Li Mengyang, Xu Jiao, Hao Jingcan, Wang Yankui, Ding Xi, Liu Yuanrui, Huang Tianlong, Fang Chao, Ge Changli, Li Dong, Hu Ke, Ren Xianwen, Zhang Baojun, Zhang Binghong, Shi Bingyin, Zhang Chengsheng, Identification of Distinct Immune Cell Subsets Associated With Asymptomatic Infection, Disease Severity, and Viral Persistence in COVID-19 Patients, Frontiers in Immunology, 13, 2022. Crossref

  53. Sharpe H R, Bowyer G, Brackenridge S, Lambe T, HLA-E: exploiting pathogen-host interactions for vaccine development, Clinical and Experimental Immunology, 196, 2, 2019. Crossref

  54. Reighard Seth D., Krishnamurthy Durga, Cevik Hilal, Ochayon David E., Ali Ayad, Seelamneni Harsha, Brunner Hermine I., Waggoner Stephen N., Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease, Cytotherapy, 23, 1, 2021. Crossref

  55. Han Na-Ra, Kim Kyeoung-Cheol, Kim Ju-Sung, Ko Seong-Gyu, Park Hi-Joon, Moon Phil-Dong, The immune-enhancing effects of a mixture of Astragalus membranaceus (Fisch.) Bunge, Angelica gigas Nakai, and Trichosanthes Kirilowii (Maxim.) or its active constituent nodakenin, Journal of Ethnopharmacology, 285, 2022. Crossref

  56. Wei Rongguo, Qin Zheng, Huang Qi, Liu Lulu, Cheng Fang, Meng Songdong, Wang Lin, A Landscape Study on COVID-19 Immunity at the Single-Cell Level, Frontiers in Immunology, 13, 2022. Crossref

  57. Zhao Hai-chao, Chen Chang-zhou, Song Huang-qin, Wang Xiao-xiao, Zhang Lei, Zhao Hao-liang, He Jie-feng, Single-cell RNA Sequencing Analysis Reveals New Immune Disorder Complexities in Hypersplenism, Frontiers in Immunology, 13, 2022. Crossref

  58. Poznanski Sophie M., Barra Nicole G., Ashkar Ali A., Schertzer Jonathan D., Immunometabolism of T cells and NK cells: metabolic control of effector and regulatory function, Inflammation Research, 67, 10, 2018. Crossref

  59. Elshal Mahmoud, Abu-Elsaad Nashwa, El-Karef Amr, Ibrahim Tarek, Etanercept attenuates immune-mediated hepatitis induced by concanavalin A via differential regulation of the key effector cytokines of CD4+ T cells, Life Sciences, 277, 2021. Crossref

  60. Alrubayyi Aljawharah, Rowland-Jones Sarah, Peppa Dimitra, Natural killer cells during acute HIV-1 infection: clues for HIV-1 prevention and therapy, AIDS, 36, 14, 2022. Crossref

  61. Strecker M.I., Wlotzka K., Strassheimer F., Roller B., Ludmirski G., König S., Röder J., Opitz C., Alekseeva T., Reul J., Sevenich L., Tonn T., Wels W.S., Steinbach J.P., Buchholz C.J., Burger M.C., AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma, OncoImmunology, 11, 1, 2022. Crossref

Forthcoming Articles

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain