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Critical Reviews™ in Immunology

Published 6 issues per year

ISSN Print: 1040-8401

ISSN Online: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Lymphokine-Dependent Proliferation of T-Lymphoid Cells: Regulated Responsiveness and Role In Vivo

Volume 21, Issue 6, 2001, 36 pages
DOI: 10.1615/CritRevImmunol.v21.i6.20
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ABSTRACT

The discovery of lymphokines stemmed from their ability to promote T-lymphocyte proliferation in vitro. Even after 20 years of in tensive investigation , crucial aspects remain to be c larified about the role of specific lymphokines in T-cell proliferation and the biochemical mechanisms by which they play these roles, particularly in vivo. The present review focuses on conventional populations of TCRab T cells. Older findings and new insights into the function of specific lymphokines in T-lymphocyte proliferation in vivo are summarized along with unanswered questions raised by these observations. Vital contributions of lymphokines to clonal proliferation arise from two processes: the protection of cells against apoptosis and the activation of cell cycling. Findings are underscored indicating that the activity of a particular lymphokine depends on the subset of T cells (CD4 vs. CD8; naive vs. memory) to which it binds, and that point to potential pitfalls of extrapolating from tissue culture-adapted models to the regulation of T cells in vivo. After summaries of signaling mechanisms related to the proliferative activity of lymphokines, recent findings are highlighted suggesting that such signaling is a regulated and plastic process rather than one fixed schema of action.

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  2. Pradier Amandine, Tabone‐Eglinger Severine, Huber Vincent, Bosshard Carine, Rigal Emmanuel, Wehrle‐Haller Bernhard, Roosnek Eddy, Peripheral bloodCD56brightNKcells respond to stem cell factor and adhere to its membrane‐bound form after upregulation of c‐kit, European Journal of Immunology, 44, 2, 2014. Crossref

  3. Shiina Masaaki, Rehermann Barbara, Hepatitis C vaccines: Inducing and challenging memory T cells, Hepatology, 43, 6, 2006. Crossref

  4. Chandele Anmol, Mukerjee Paushali, Das Gobardhan, Ahmed Rafi, Chauhan Virander S., Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii, Immunology, 132, 2, 2011. Crossref

  5. Zambricki Elizabeth, Shigeoka Alana, Kishimoto Hidehiro, Sprent Jon, Burakoff Steven, Carpenter Charles, Milford Edgar, McKay Dianne, Signaling T-Cell Survival and Death by IL-2 and IL-15, American Journal of Transplantation, 5, 11, 2005. Crossref

  6. Wang Jue, Hu Yin, Nekvindova Jana, Ingelman-Sundberg Magnus, Neve Etienne P.A., IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways, Biochemical Pharmacology, 80, 10, 2010. Crossref

  7. Muul Linda Mesler, Silvin Christopher, James Stephen P., Candotti Fabio, Measurement of Proliferative Responses of Cultured Lymphocytes, in Current Protocols in Immunology, 2008. Crossref

  8. Schwartz Julie A., Aldridge Brian M., Stott Jeff L., Mohr F.Charles, Immunophenotypic and functional effects of bunker C fuel oil on the immune system of American mink (Mustela vison), Veterinary Immunology and Immunopathology, 101, 3-4, 2004. Crossref

  9. Muul Linda Mesler, Heine Guido, Silvin Christopher, James Stephen P., Candotti Fabio, Radbruch Andreas, Worm Margitta, Measurement of Proliferative Responses of Cultured Lymphocytes, Current Protocols in Immunology, 94, 1, 2011. Crossref

  10. Kaech Susan M, Tan Joyce T, Wherry E John, Konieczny Bogumila T, Surh Charles D, Ahmed Rafi, Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells, Nature Immunology, 4, 12, 2003. Crossref

  11. Atwal Onkar S., McDonell Wayne, In situ response of lung circulating leukocytes to volatile and injectable anesthetics in ponies. Enigma of stimulated pulmonary intravascular macrophages and lymphoproliferation: a comparative ultrastructural, cytochemical and morphometric study, Comparative Clinical Pathology, 16, 3, 2007. Crossref

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  13. Cho Sung Hoon, Ahn Annie K., Bhargava Prerna, Lee Chih-Hao, Eischen Christine M., McGuinness Owen, Boothby Mark, Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family, Proceedings of the National Academy of Sciences, 108, 38, 2011. Crossref

  14. Heller Nicola M., Qi Xiulan, Junttila Ilkka S., Shirey Kari Ann, Vogel Stefanie N., Paul William E., Keegan Achsah D., Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages, Science Signaling, 1, 51, 2008. Crossref

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