Published 6 issues per year
ISSN Print: 0743-4863
ISSN Online: 2162-660X
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Regional Variation in Oral Mucosal Drug Permeability
ABSTRACT
The purpose of this article is to review regional variation in oral mucosal drug permeability. The structure and composition of the mucosa at different sites in the oral cavity, factors affecting mucosal permeability, selection of appropriate experimental systems for studying mucosal permeability, and formulation factors including penetration enhancement relevant to the design of systems for oral mucosal delivery are reviewed.
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Paderni Carlo, Compilato Domenico, Giannola Libero Italo, Campisi Giuseppina, Oral local drug delivery and new perspectives in oral drug formulation, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 114, 3, 2012. Crossref
-
Lee Hye J., Choi Chanmi, Oral Delivery of Macromolecules for the Development of Therapeutic Agents, in Pharmaceutical Sciences Encyclopedia, 2011. Crossref
-
Jangra Shelly, Ahuja Munish, Kumar Ashok, Evaluation of mucoadhesive property of gum ghatti, Journal of Pharmaceutical Investigation, 43, 6, 2013. Crossref
-
Aframian DJ, Davidowitz T, Benoliel R, The distribution of oral mucosal pH values in healthy saliva secretors, Oral Diseases, 12, 4, 2006. Crossref
-
Singh Rajesh, Singh Shailesh, Lillard James W., Past, Present, and Future Technologies for Oral Delivery of Therapeutic Proteins, Journal of Pharmaceutical Sciences, 97, 7, 2008. Crossref
-
Lee Hye J., Protein drug oral delivery: The recent progress, Archives of Pharmacal Research, 25, 5, 2002. Crossref
-
Novak Natalija, Haberstok Jörg, Bieber Thomas, Allam Jean-Pierre, The immune privilege of the oral mucosa, Trends in Molecular Medicine, 14, 5, 2008. Crossref
-
Caon Thiago, Simões Cláudia Maria Oliveira, Effect of Freezing and Type of Mucosa on Ex Vivo Drug Permeability Parameters, AAPS PharmSciTech, 12, 2, 2011. Crossref
-
Goswami Tarun, Jasti Bhaskara R., Li Xiaoling, Estimation of the theoretical pore sizes of the porcine oral mucosa for permeation of hydrophilic permeants, Archives of Oral Biology, 54, 6, 2009. Crossref
-
Buccal Route and Ingestion, in Nanomedicines and Nanoproducts, 2015. Crossref
-
Smart John D., Keegan Gemma, Buccal Drug Delivery Systems, in Oral Controlled Release Formulation Design and Drug Delivery, 2010. Crossref
-
Sohi Harmik, Ahuja Alka, Ahmad Farhan Jalees, Khar Roop Krishen, Critical evaluation of permeation enhancers for oral mucosal drug delivery, Drug Development and Industrial Pharmacy, 36, 3, 2010. Crossref
-
Rahbarian Marzieh, Mortazavian Elahe, Dorkoosh Farid Abedin, Rafiee Tehrani Morteza, Preparation, evaluation and optimization of nanoparticles composed of thiolated triethyl chitosan: A potential approach for buccal delivery of insulin, Journal of Drug Delivery Science and Technology, 44, 2018. Crossref
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Garzón Ingrid, Serrato Deyanira, Roda Olga, Del Carmen Sánchez-Quevedo María, González-Jaranay Maximino, Moreu Gerardo, Nieto-Aguilar Renato, Alaminos Miguel, Campos Antonio, In vitro Cytokeratin Expression Profiling of Human Oral Mucosa Substitutes Developed by Tissue Engineering, The International Journal of Artificial Organs, 32, 10, 2009. Crossref
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Sofi Hasham S., Abdal-hay Abdalla, Ivanovski Saso, Zhang Yu Shrike, Sheikh Faheem A., Electrospun nanofibers for the delivery of active drugs through nasal, oral and vaginal mucosa: Current status and future perspectives, Materials Science and Engineering: C, 111, 2020. Crossref