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Critical Reviews™ in Therapeutic Drug Carrier Systems
IF: 2.414 5-Year IF: 3.324 SJR: 0.573 SNIP: 0.551 CiteScore™: 2.43

ISSN Print: 0743-4863
ISSN Online: 2162-660X

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v19.i2.10
36 pages

Nanocapsule Technology: A Review

Patrick Couvreur
Universite de Paris-Sud, UMR CNRS 8612, 5 rue J-B Clement, 92296 Chatenay-Malabry, France
Gillian Barratt
Universite de Paris-Sud, UMR CNRS 8612, 5 rue J-B Clement, 92296 Chatenay-Malabry, France
Elias Fattal
Universite de Paris-Sud, UMR CNRS 8612, 5 rue J-B Clement, 92296 Chatenay-Malabry, France
Christine Vauthier
Universite de Paris-Sud, UMR CNRS 8612, 5 rue J-B Clement, 92296 Chatenay-Malabry, France

ABSTRACT

Nanocapsules are submicroscopic colloidal drug carrier systems composed of an oily or an aqueous core surrounded by a thin polymer membrane. Two technologies can be used to obtain such nanocapsules: the interracial polymerization of a monomer or the interfacial nanodeposition of a preformed polymer. This article is an extended review of these nanocapsule technologies and their applications for the treatment of various diseases (including cancer and infections).