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Critical Reviews™ in Therapeutic Drug Carrier Systems

Published 6 issues per year

ISSN Print: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

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Major Determinants in Hepatic Disposition of Polystyrene Nanospheres: Implication for Rational Design of Particulate Drug Carriers

Volume 19, Issue 4-5, 2002, 30 pages
DOI: 10.1615/CritRevTherDrugCarrierSyst.v19.i45.10
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ABSTRACT

The clearance of colloidal particles from the blood circulation occurs by phagocytes and/or endothelial cells, mainly in the liver, the spleen, and the bone marrow. The relative distribution of the injected particles in these organs is known to depend on various factors such as the size and surface properties of the particles and the type of serum proteins adsorbed onto the surface of particles. The basic principles behind their distribution characteristics into the reticuloendothelial system, however, remain unclear. This article reviews major determinants in hepatic disposition of polystyrene nanospheres, especially the relationship among physicochemical properties of the particle surface, the type of blood components associated onto the surface of particles, and their in vivo disposition characteristics in rats, and considerations to be given and implication for the rational design of particulate drug carriers are discussed.

CITED BY
  1. Taglienti Anna, Cellesi Francesco, Crescenzi Vittorio, Sequi Paolo, Valentini Massimiliano, Tirelli Nicola, Investigating the Interactions of Hyaluronan Derivatives with Biomolecules. The Use of Diffusional NMR Techniques, Macromolecular Bioscience, 6, 8, 2006. Crossref

  2. Straub Julie A., Chickering Donald E., Lovely Jonathan C., Zhang Huimin, Shah Bhavdeep, Waud William R., Bernstein Howard, Intravenous Hydrophobic Drug Delivery: A Porous Particle Formulation of Paclitaxel (AI-850), Pharmaceutical Research, 22, 3, 2005. Crossref

  3. Ben-Shabat Shimon, Kumar Neeraj, Domb Abraham J., PEG-PLA Block Copolymer as Potential Drug Carrier: Preparation and Characterization, Macromolecular Bioscience, 6, 12, 2006. Crossref

  4. Thassu Deepak, Pathak Yashwant, Deleers Michel, Nanoparticulate Drug-Delivery Systems, in Nanoparticulate Drug Delivery Systems, 20075578, 2007. Crossref

  5. Shi Bin, Keough Ed, Matter Andrea, Leander Karen, Young Stephanie, Carlini Ed, Sachs Alan B., Tao Weikang, Abrams Marc, Howell Bonnie, Sepp-Lorenzino Laura, Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery, Journal of Histochemistry & Cytochemistry, 59, 8, 2011. Crossref

  6. Lu Dan, Wientjes M. Guillaume, Lu Ze, Au Jessie L.-S., Tumor Priming Enhances Delivery and Efficacy of Nanomedicines, Journal of Pharmacology and Experimental Therapeutics, 322, 1, 2007. Crossref

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