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Critical Reviews™ in Oncogenesis
SJR: 0.631 SNIP: 0.503 CiteScore™: 2

ISSN Print: 0893-9675
ISSN Online: 2162-6448

Critical Reviews™ in Oncogenesis

DOI: 10.1615/CritRevOncog.v7.i5-6.20
pages 343-432

Protein Phosphorylation and Dephosphorylation in Physiologic and Oncologic Processes

Roberto Patarca
Cordis Corporation, Miami Lakes, FL 33014

ABSTRACT

Phosphorylation and dephosphorylation of proteins is an important regulatory mechanism of cell metabolism, proliferation and differentiation. The present review summarizes the known key players, their interactions, effects on physiological processes, and their role in pathology and neoplasia.


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