Library Subscription: Guest
Home Begell Digital Library eBooks Journals References & Proceedings Research Collections
Critical Reviews™ in Biomedical Engineering

ISSN Print: 0278-940X
ISSN Online: 1943-619X

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v27.i1-2.10
pages 1-25

Techniques of CT Colonography (Virtual Colonoscopy)

Ventzeslav Valev
The University of Iowa, College of Medicine, Department of Radiology, 200 Hawkins Dr. 3984 JPP, Iowa City, IA 52242-1077; Bulgarian Academy of Sciences, Institute of Mathematics and Informatics, Acad. G. Bontchev Street, Bl. 8, 1113 Sofia, Bulgaria
Ge Wang
The University of Iowa, College of Medicine, Department of Radiology, 200 Hawkins Dr. 3984 JPP, Iowa City, IA 52242-1077
Michael W. Vannier
The University of Iowa, College of Medicine, Department of Radiology, 200 Hawkins Dr. 3984 JPP, Iowa City, IA 52242-1077

ABSTRACT

Colorectal cancer is a leading cause of death in older adults, which usually involves a long-term progressive change of normal mucosa into adenomatous polyps and then cancer. The detection and treatment of this disease in an early stage can lead to a cure in most cases by simply removing the polyp. Computed tomographic colonography (CTC), also referred to as virtual colonoscopy (VC), is a recent advance that gives an intraluminal visualization of the colon that is similar to endoscopy. VC requires fast 3D display (at least 10 frames/sec) of the colon's mucosal surface on a computer screen. Spiral/helical computer tomography is used to gather 3D volume data prior to display. CTC has been demonstrated to be promising for colorectal cancer screening. Studies on unraveling of the colon are underway to map the convoluted tubular structure into a straightened and flattened image volume for global visualization. In this article, we review the current status of CTC with an emphasis on image processing and visualization algorithms. Clinical assessment results of existing techniques are summarized. Practical issues and future perspectives are also discussed.