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High Temperature Material Processes: An International Quarterly of High-Technology Plasma Processes
SJR: 0.19 SNIP: 0.341 CiteScore™: 0.43

ISSN Print: 1093-3611
ISSN Online: 1940-4360

High Temperature Material Processes: An International Quarterly of High-Technology Plasma Processes

DOI: 10.1615/HighTempMatProc.v13.i3-4.60
pages 325-334

UPPERMOLECULE COMPLEXES OF OXIDE NANOSTRUCTURES AND ALBUMINS FORMATION

Philip G. Rutberg
Institute of Problems of Electrophysics of Russian Academy of Sciences 191186, Russia, St. Petersburg, Dvortsovaya nab. 18
V. A. Kolikov
Institute for Electrophysics and Electric Power Russian Academy of Science, 191186, Dvortsovaya nab. 18, St. Petersburg
V. Snetov
Institute for Electrophysics and Electric Power Russian Academy of Science, 191186, Dvortsovaya nab. 18, St. Petersburg
A. Stogov
Institute for Electrophysics and Electric Power Russian Academy of Science, 191186, Dvortsovaya nab. 18, St. Petersburg
L. Noskin
Institute for Nuclear Physics Russian Academy of Science, 188300, Gatchina
S. Landa
Institute for Nuclear Physics Russian Academy of Science, 188300, Gatchina
A. Arutjunan
Institute for Nuclear Physics Russian Academy of Science, 188300, Gatchina
V. Egorov
Institute for Nuclear Physics Russian Academy of Science, 188300, Gatchina; Unstitute for Influenza Russian Academy of Medicine Science, 197376, prof. Popov st. 15, St., Petersburg
A. Sirotkin
Unstitute for Influenza Russian Academy of Medicine Science, 197376, prof. Popov st. 15, St., Petersburg

ABSTRACT

Possible employment of oxide nanostructures in medicine demands elucidation of their negative effects on various systems of a human organism. In particular, in this paper the experimental results of investigation of interaction of Ag, Cu, Fe, and Pt nanostructures water dispersions (NWD), which were produced by means the treatment of water by pulsed electric discharges (PED), with serum of human blood (HBS), are presented. The goal of the investigation was to determine connection between the properties of the nanostructures and peculiarities of their interactions with the human blood serum (HBS) as highly concentrated solutions of macromolecules. It was found that albuminous and lipoprotein structures of HBS are agglutinated on surface of the nanoparticles, forming upper molecule complexes. Thus, the higher the concentration of nanoparticles in joint dispersion is, the larger complexes are formed. At early stages of the process rather small complexes of albuminous and immunoglobulins are formed, then lipoproteins are agglutinated, and finally, large complexes of hydrodynamic radius (Rh) more than 2 μm are formed.


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