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Plasma Medicine
SJR: 0.198 SNIP: 0.183 CiteScore™: 0.57

ISSN Print: 1947-5764
ISSN Online: 1947-5772

Plasma Medicine

DOI: 10.1615/PlasmaMed.2017019317
pages 429-446

Non-Thermal Atmospheric Dielectric Barrier Discharge Plasma, Medical Application Studies in Thailand

Chanchai Chutsirimongkol
Thailand Center of Excellence for Life Sciences, Bangkok, 10400, Thailand/PhotoBioCare Co., Ltd., Nonthaburi 11120, Thailand
Dheerawan Boonyawan
Chiang Mai University, Chiang Mai 50200, Thailand
Niwat Polnikorn
Kasemrad Hospital, Bangkok 10240, Thailand
Wasini Techawatthanawisan
Mae Fah Luang University, Bangkok 10110, Thailand
Treenuch Kundilokchai
Mae Fah Luang University, Bangkok 10110, Thailand
Chayanid Bunsaisup
Mae Fah Luang University, Bangkok 10110, Thailand
Paisal Rummaneethorn
Mae Fah Luang University, Bangkok 10110, Thailand
Wicharn Kirdwichai
Burapha University, Chonburi 20130, Thailand
Apirag Chuangsuwanich
Surgery Department, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
Pannapa Powthong
Rangsit University, Pathum Thani 12000, Thailand


Atmospheric Dielectric Barrier Discharge (DBD) plasma development is one of the most interesting subjects to our group. Fridman et al.* has concluded that Floating DBD Direct Plasma are more effective in bactericidal property, it contains higher free charged particles than indirect type. DBD plasma sources can provide low temperature or non-thermal (cold) plasmas, and these plasmas can be created with ambient air or with a noble gas, such as helium or argon, as the carrier medium. It can be used with an electrode as a contact or non-contact method to target a tissue. However, the drawback of direct DBD plasma is that it will work only in short gap distances, on the order of a few millimeters. Our group has investigated the clinical safety and efficacy of a novel DBD non-thermal atmospheric plasma source (BIO-PLASMA Cell Modulation: PhotoBioCare, Thailand). The major area has been focused on its bactericidal disinfection property, application in common dermatologic problems, in skin aesthetic facial rejuvenation and chronic wound management, from 2012 to 2016.