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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Expression of Members of the Dystrophin, Dystrobrevin, and Dystrotelin Superfamily

Volume 19, Issue 2, 2009, pp. 89-108
DOI: 10.1615/CritRevEukarGeneExpr.v19.i2.10
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ABSTRACT

The dystrophin/dystrobrevin/dystrotelin superfamily is marked by a common constellation of domains whose juxtaposition is tightly constrained in all three subfamilies. These domains comprise a cluster of four closely packed EF hands, a ZZ domain, and two coiled-coil regions. In addition, the dystrophin and dystrobrevin branches share one or two binding sites for members of the syntrophin family of adaptor proteins, and the dystrophins and some dystrotelins share a WW domain. Much of the exon structure of the genes encoding these domains is also shared, confirming the monophyletic status of the superfamily. Almost all animals have at least one member of each branch, with multiple paralogous members of the dystrophin and dystrobrevin branches in the vertebrates. Thus, in humans, 6 genes, 19 promoters, and 10 alternatively spliced exons conspire to generate a staggering array of proteins, with at least one in almost every tissue of the body. This review aims to summarize what is known of this complexity of expression of members of the dystrophin/dystrobrevin/dystrotelin superfamily across the animal kingdom. The widespread expression in adult vertebrates, together with elaborate and dynamic patterns during development, paints a picture of a superfamily whose fundamental biological function is still poorly understood.

CITED BY
  1. Gurniak Christine B., Chevessier Frédéric, Jokwitz Melanie, Jönsson Friederike, Perlas Emerald, Richter Hendrik, Matern Gabi, Boyl Pietro Pilo, Chaponnier Christine, Fürst Dieter, Schröder Rolf, Witke Walter, Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance, European Journal of Cell Biology, 93, 5-6, 2014. Crossref

  2. Massouridès Emmanuelle, Polentes Jérôme, Mangeot Philippe-Emmanuel, Mournetas Virginie, Nectoux Juliette, Deburgrave Nathalie, Nusbaum Patrick, Leturcq France, Popplewell Linda, Dickson George, Wein Nicolas, Flanigan Kevin M., Peschanski Marc, Chelly Jamel, Pinset Christian, Dp412e: a novel human embryonic dystrophin isoform induced by BMP4 in early differentiated cells, Skeletal Muscle, 5, 1, 2015. Crossref

  3. Mornet Dominique, Rivier François, Quel avenir pour la dystrophine ?, Les Cahiers de Myologie, 15, 2017. Crossref

  4. Dowling Paul, Murphy Sandra, Zweyer Margit, Raucamp Maren, Swandulla Dieter, Ohlendieck Kay, Emerging proteomic biomarkers of X-linked muscular dystrophy, Expert Review of Molecular Diagnostics, 19, 8, 2019. Crossref

  5. Navakauskienė Rūta, Navakauskas Dalius, Borutinskaitė Veronika, Matuzevičius Dalius, Protein Phosphorylation in Leukemia, in Epigenetics and Proteomics of Leukemia, 2021. Crossref

  6. Böhm Sabrina V, Constantinou Panayiotis, Tan Sipin, Jin Hong, Roberts Roland G, Profound human/mouse differences in alpha-dystrobrevin isoforms: a novel syntrophin-binding site and promoter missing in mouse and rat , BMC Biology, 7, 1, 2009. Crossref

  7. Ohlendieck Kay, Swandulla Dieter, Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy, Pflügers Archiv - European Journal of Physiology, 473, 12, 2021. Crossref

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