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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Control of Tumor Necrosis Factor Gene Expression

Volume 4, Issue 2-3, 1994, pp. 323-344
DOI: 10.1615/CritRevEukarGeneExpr.v4.i2-3.20
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ABSTRACT

This review summarizes the known data about transcriptional control of the tumor necrosis factor genes. Mechanisms of transcriptional induction of TNF gene expression and the influences of regulatory elements in the promter and in the 3' flanking regions are discussed. Posttranscriptional events that influence regulation of TNF gene expression such as destabilization of mRNA are described. The influence of chromatin structure and possible functional implications are also reported. Although their biological effects largely overlap, it is concluded that the TNFα and TNFβ genes are differently regulated at the transcriptional level.

CITED BY
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  4. Yoshie Hiromasa, Kobayashi Tetsuo, Tai Hideaki, Galicia Johnah C., The role of genetic polymorphisms in periodontitis, Periodontology 2000, 43, 1, 2007. Crossref

  5. Bailey LeeAnn O., Washburn Newell R., Simon Carl G., Chan Edward S., Wang Francis W., Quantification of inflammatory cellular responses using real-time polymerase chain reaction, Journal of Biomedical Materials Research, 69A, 2, 2004. Crossref

  6. Lu Linrong, Zhu Jinfang, Zheng Zhongcheng, Yan Mingda, Xu Weijin, Sun Lanyin, Theze Jacque, Liu Xinyuan, Jak-STAT pathway is involved in the induction ofTNF-β gene during stimulation by IL-2, European Journal of Immunology, 28, 3, 1998. Crossref

  7. Baghel Kavita, Srivastava Rajeshwar Nath, Chandra Abhijit, Raj Saloni, Goel Sudhir K., Pant Aditya Bhusan, Agrawal Jyotsna, Tumor Necrosis Factor-β Nco1 Polymorphism and Susceptibility to Sepsis following Major Elective Surgery, Surgical Infections, 15, 3, 2014. Crossref

  8. Xu Weijing, Yan Mingda, Lu Linrong, Sun Lanying, Theze Jacque, Zheng Zhongcheng, Liu Xinyuan, The p38 MAPK Pathway Is Involved in the IL-2 Induction of TNF-β Gene via the EBS Element, Biochemical and Biophysical Research Communications, 289, 5, 2001. Crossref

  9. Lv K., Chen R., Cai Q., Fang M., Sun S., Effects of a Single Nucleotide Polymorphism on the Expression of Human Tumor Necrosis Factor-alpha, Scandinavian Journal of Immunology, 64, 2, 2006. Crossref

  10. Trebichavský I., Šplíchal I., Barot-Ciorbaru R., Expression of TNF-α in pig fetal cells stimulatedin Vitro, Folia Microbiologica, 40, 4, 1995. Crossref

  11. Butchi Niranjan B., Du Min, Peterson Karin E., Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia, Glia, 2009. Crossref

  12. Wong Shu-shyan, Schwartz Richard C., Pestka James J., Superinduction of TNF-α and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization, Toxicology, 161, 1-2, 2001. Crossref

  13. Diehl Anna Mae, Tumor necrosis factor and its potential role in insulin resistance and nonalcoholic fatty liver disease, Clinics in Liver Disease, 8, 3, 2004. Crossref

  14. Diehl Anna Mae, ALCOHOL AND LIVER REGENERATION, Clinics in Liver Disease, 2, 4, 1998. Crossref

  15. Heesen Michael, Kunz Dagmar, Bachmann-Mennenga Bernd, Merk Hans F., Bloemeke Brunhilde, Linkage disequilibrium between tumor necrosis factor (TNF)-α–308 G/A promoter and TNF-βNco I polymorphisms: Association with TNF-α response of granulocytes to endotoxin stimulation, Critical Care Medicine, 31, 1, 2003. Crossref

  16. Majetschak Matthias, Flohé Sascha, Obertacke Udo, Schröder Jörg, Staubach Karl, Nast-Kolb Dieter, Schade F. Ulrich, Stüber Frank, Relation of a TNF Gene Polymorphism to Severe Sepsis in Trauma Patients, Annals of Surgery, 230, 2, 1999. Crossref

  17. Klegeris Andis, Walker Douglas G, McGeer Patrick L, Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α, Brain Research, 747, 1, 1997. Crossref

  18. Wajant Harald, Siegmund Daniela, TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages, Frontiers in Cell and Developmental Biology, 7, 2019. Crossref

  19. Majetschak Matthias, Obertacke Udo, Schade F. Ulrich, Bardenheuer Mark, Voggenreiter Gregor, Bloemeke Brunhilde, Heesen Michael, Tumor Necrosis Factor Gene Polymorphisms, Leukocyte Function, and Sepsis Susceptibility in Blunt Trauma Patients, Clinical and Vaccine Immunology, 9, 6, 2002. Crossref

  20. Bayley J-P, Ottenhoff T H M, Verweij C L, Is there a future for TNF promoter polymorphisms?, Genes & Immunity, 5, 5, 2004. Crossref

  21. Hoffmeyer Angelika, Grosse-Wilde Anne, Flory Egbert, Neufeld Bernd, Kunz Manfred, Rapp Ulf R., Ludwig Stephan, Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes, Journal of Biological Chemistry, 274, 7, 1999. Crossref

  22. Baer Mark, Dillner Allan, Schwartz Richard C., Sedon Constance, Nedospasov Sergei, Johnson Peter F., Tumor Necrosis Factor Alpha Transcription in Macrophages Is Attenuated by an Autocrine Factor That Preferentially Induces NF-κB p50, Molecular and Cellular Biology, 18, 10, 1998. Crossref

  23. Pausova Zdenka, Sedova Lucie, Berube Julie, Hamet Pavel, Tremblay Johanne, Dumont Marc, Gaudet Daniel, Pravenec Michal, Kren Vladimir, Kunes Jaroslav, Segment of Rat Chromosome 20 Regulates Diet-Induced Augmentations in Adiposity, Glucose Intolerance, and Blood Pressure, Hypertension, 41, 5, 2003. Crossref

  24. Yang Shi Qi, Lin Hui Zhi, Lane M. Daniel, Clemens Mark, Diehl Anna Mae, Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis, Proceedings of the National Academy of Sciences, 94, 6, 1997. Crossref

  25. Tribouillard-Tanvier Déborah, Striebel James F., Peterson Karin E., Chesebro Bruce, Analysis of Protein Levels of 24 Cytokines in Scrapie Agent-Infected Brain and Glial Cell Cultures from Mice Differing in Prion Protein Expression Levels, Journal of Virology, 83, 21, 2009. Crossref

  26. Dean Jonathan L. E., Wait Robin, Mahtani Kamal R., Sully Gareth, Clark Andrew R., Saklatvala Jeremy, The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR, Molecular and Cellular Biology, 21, 3, 2001. Crossref

  27. Kishore Raj, McMullen Megan R., Nagy Laura E., Stabilization of Tumor Necrosis Factor α mRNA by Chronic Ethanol, Journal of Biological Chemistry, 276, 45, 2001. Crossref

  28. Shoji Youko, Inoue Yuuki, Sugisawa Hitoshi, Itou Takuya, Endo Tomoko, Sakai Takeo, Molecular cloning and functional characterization of bottlenose dolphin (Tursiops truncatus) tumor necrosis factor alpha, Veterinary Immunology and Immunopathology, 82, 3-4, 2001. Crossref

  29. Deree Jessica, Martins Joilson O., Melbostad Heidi, Loomis William H., Coimbra Raul, Insights into the Regulation of TNF-α Production in Human Mononuclear Cells: The Effects of Non-Specific Phosphodiesterase Inhibition, Clinics, 63, 3, 2008. Crossref

  30. Chen Bing‐Chang, Hsieh Shie‐Liang, Lin Wan‐Wan, Involvement of protein kinases in the potentiation of lipopolysaccharide‐induced inflammatory mediator formation by thapsigargin in peritoneal macrophages, Journal of Leukocyte Biology, 69, 2, 2001. Crossref

  31. Kuprash Dmitry V., Udalova Irina A., Turetskaya Regina L., Kwiatkowski Dominic, Rice Nancy R., Nedospasov Sergei A., Similarities and Differences Between Human and Murine TNF Promoters in Their Response to Lipopolysaccharide, The Journal of Immunology, 162, 7, 1999. Crossref

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