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Critical Reviews™ in Eukaryotic Gene Expression

Published 6 issues per year

ISSN Print: 1045-4403

ISSN Online: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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The Effects of Nrf2 on Tumor Angiogenesis: A Review of the Possible Mechanisms of Action

Volume 22, Issue 2, 2012, pp. 149-160
DOI: 10.1615/CritRevEukarGeneExpr.v22.i2.60
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ABSTRACT

To date, preclinical and clinical data have shown that various cancer patients benefit from antiangiogenic therapy because of the important role of angiogenesis in the tumor development process. NF-E2−related factor 2 (Nrf2) is recognized as a key transcription factor of genes coding for various antioxidant and cytoprotective enzymes, and Nrf2 plays important roles during tumor progression. Recent studies have begun to explore the role of Nrf2 in tumor angiogenesis, which may be to promote the advancement of tumor antiangiogenic therapy. This article reviews the Nrf2-related pathways involved in tumor angiogenesis and summarizes the possible mechanisms of Nrf2 action as a pro-angiogenic factor in tumor progression.

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  2. Maes Hannelore, Rubio Noemí, Garg Abhishek D., Agostinis Patrizia, Autophagy: shaping the tumor microenvironment and therapeutic response, Trends in Molecular Medicine, 19, 7, 2013. Crossref

  3. Bao Bin, Ahmad Aamir, Azmi Asfar, Li Yiwei, Prasad Ananda, Sarkar Fazlul H., The Biological Significance of Zinc in Inflammation and Aging, in Inflammation, Advancing Age and Nutrition, 2014. Crossref

  4. van der Wijst Monique G.P., Brown Robert, Rots Marianne G., Nrf2, the master redox switch: The Achilles' heel of ovarian cancer?, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1846, 2, 2014. Crossref

  5. Prasad Ananda S., Zinc, Oxidative Stress in the Elderly and Implications for Inflammation, in Aging, 2014. Crossref

  6. Gjyshi Olsi, Bottero Virginie, Veettil Mohanan Valliya, Dutta Sujoy, Singh Vivek Vikram, Chikoti Leela, Chandran Bala, Swaminathan Sankar, Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 during De Novo Infection of Endothelial Cells to Create a Microenvironment Conducive to Infection, PLoS Pathogens, 10, 10, 2014. Crossref

  7. ZHU JIANHONG, WANG HANDONG, FAN YOUWU, LIN YIXING, ZHANG LI, JI XIANGJUN, ZHOU MENGLIANG, Targeting the NF-E2-related factor 2 pathway: A novel strategy for glioblastoma (Review), Oncology Reports, 32, 2, 2014. Crossref

  8. Fan Z, Wirth A-K, Chen D, Wruck C J, Rauh M, Buchfelder M, Savaskan N, Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis, Oncogenesis, 6, 8, 2017. Crossref

  9. Tertil Magdalena, Skrzypek Klaudia, Łoboda Agnieszka, Angiogenic Signaling and Structural Abnormalities in Tumors, in Angiogenesis and Vascularisation, 2013. Crossref

  10. Florczyk Urszula, Józkowicz Alicja, Dulak Józef, Nrf2 Transcription Factor and Heme Oxygenase-1 as Modulators of Vascular Injury and Angiogenesis, in Angiogenesis and Vascularisation, 2013. Crossref

  11. Cernigliaro Cesare, D’Anneo Antonella, Carlisi Daniela, Giuliano Michela, Marino Gammazza Antonella, Barone Rosario, Longhitano Lucia, Cappello Francesco, Emanuele Sonia, Distefano Alfio, Campanella Claudia, Calvaruso Giuseppe, Lauricella Marianna, Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway, Cancers, 11, 4, 2019. Crossref

  12. Prasad Ananda S., Bao Bin, Molecular Mechanisms of Zinc as a Pro-Antioxidant Mediator: Clinical Therapeutic Implications, Antioxidants, 8, 6, 2019. Crossref

  13. Nakamura Shinsuke, Noguchi Tetsuro, Inoue Yuki, Sakurai Shuji, Nishinaka Anri, Hida Yoshifumi, Masuda Tomomi, Nakagami Yasuhiro, Horai Naoto, Tsusaki Hideshi, Hara Hideaki, Shimazawa Masamitsu, Nrf2 Activator RS9 Suppresses Pathological Ocular Angiogenesis and Hyperpermeability, Investigative Opthalmology & Visual Science, 60, 6, 2019. Crossref

  14. Nabih Heba K., Crosstalk between NRF2 and Dicer through metastasis regulating MicroRNAs; mir-34a, mir-200 family and mir-103/107 family, Archives of Biochemistry and Biophysics, 686, 2020. Crossref

  15. Prasad Ananda S., Bao Bin, Zinc, oxidative stress in the elderly, and implication for inflammation, in Aging, 2020. Crossref

  16. Stuchi Leonardo P., Castanhole-Nunes Márcia Maria U., Maniezzo-Stuchi Nathália, Biselli-Chicote Patrícia M., Henrique Tiago, Padovani Neto João Armando, de-Santi Neto Dalisio, Girol Ana Paula, Pavarino Erika C., Goloni-Bertollo Eny Maria, VEGFA and NFE2L2 Gene Expression and Regulation by MicroRNAs in Thyroid Papillary Cancer and Colloid Goiter, Genes, 11, 9, 2020. Crossref

  17. Ambrosio Leanne, Argenziano Monica, Cucci Marie Angèle, Grattarola Margherita, de Graaf Inge A.M., Dianzani Chiara, Barrera Giuseppina, Sánchez Nieves Javier, Gomez Rafael, Cavalli Roberta, Pizzimenti Stefania, Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells, Antioxidants, 9, 10, 2020. Crossref

  18. Zhang Mingxin, Zhang Chao, Zhang Lingmin, Yang Qi, Zhou Suna, Wen Qinsheng, Wang Jingjie, Nrf2 is a potential prognostic marker and promotes proliferation and invasion in human hepatocellular carcinoma, BMC Cancer, 15, 1, 2015. Crossref

  19. Pizzimenti Stefania, Ribero Simone, Cucci Marie Angele, Grattarola Margherita, Monge Chiara, Dianzani Chiara, Barrera Giuseppina, Muzio Giuliana, Oxidative Stress-Related Mechanisms in Melanoma and in the Acquired Resistance to Targeted Therapies, Antioxidants, 10, 12, 2021. Crossref

  20. Sukumari-Ramesh Sangeetha, Prasad Niyathi, Alleyne Cargill H, Vender John R, Dhandapani Krishnan M, Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells, BMC Cancer, 15, 1, 2015. Crossref

  21. Gjyshi Olsi, Roy Arunava, Dutta Sujoy, Veettil Mohanan Valiya, Dutta Dipanjan, Chandran Bala, Longnecker R. M., Activated Nrf2 Interacts with Kaposi's Sarcoma-Associated Herpesvirus Latency Protein LANA-1 and Host Protein KAP1 To Mediate Global Lytic Gene Repression, Journal of Virology, 89, 15, 2015. Crossref

  22. Gjyshi Olsi, Flaherty Stephanie, Veettil Mohanan Valiya, Johnson Karen E., Chandran Bala, Bottero Virginie, Hutt-Fletcher L., Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 Activation in Latently Infected Endothelial Cells through SQSTM1 Phosphorylation and Interaction with Polyubiquitinated Keap1, Journal of Virology, 89, 4, 2015. Crossref

  23. Serrano José J., Delgado Belén, Medina Miguel Ángel, Control of tumor angiogenesis and metastasis through modulation of cell redox state, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1873, 2, 2020. Crossref

  24. Kumar Hitesh, Kumar Rachna M., Bhattacharjee Devanjali, Somanna Preethi, Jain Vikas, Role of Nrf2 Signaling Cascade in Breast Cancer: Strategies and Treatment, Frontiers in Pharmacology, 13, 2022. Crossref

  25. Emami Mohammad Hassan, Sereshki Nasrin, Malakoutikhah Zahra, Dehkordi Sayed Ali Ehsan, Fahim Alireza, Mohammadzadeh Samane, Maghool Fatemeh, Nrf2 signaling pathway in trace metal carcinogenesis: A cross-talk between oxidative stress and angiogenesis, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 254, 2022. Crossref

  26. Argenziano Monica, Bessone Federica, Dianzani Chiara, Cucci Marie Angèle, Grattarola Margherita, Pizzimenti Stefania, Cavalli Roberta, Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma, Pharmaceutics, 14, 2, 2022. Crossref

  27. Awuah Wireko Andrew, Toufik Abdul-Rahman, Yarlagadda Rohan, Mikhailova Tatiana, Mehta Aashna, Huang Helen, Kundu Mrinmoy, Lopes Leilani, Benson Sylvester, Mykola Lyndin, Vladyslav Sikora, Alexiou Athanasios, Alghamdi Badrah S., Hashem Anwar M., Md Ashraf Ghulam, Exploring the role of Nrf2 signaling in glioblastoma multiforme, Discover Oncology, 13, 1, 2022. Crossref

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