Published 12 issues per year
ISSN Print: 1521-9437
ISSN Online: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Methanolic Soluble Fractions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes) Extract Inhibit Neuraminidase Activity in Newcastle Disease Virus (LaSota)
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ABSTRACT
The antineuraminidase activity of different organic soluble fractions of Ganoderma lucidum extract was investigated using inhibition of hemagglutination and elution of chicken erythrocytes by Newcastle disease virus (NDV). Fractions of methanol, ethylacetate, and normal butanol (n-butanol) of the G. lucidum were tested against neuraminidase producing NDV as antigen. Different dilutions of the organic soluble fractions inhibited elution of 1% red blood cells by neuraminidase of NDV While the methanolic and n-butanol extracts inhibited neuraminidase activity even at a dilution of 1:16 and that of ethylacetate fraction inhibited even at 1:32 respectively. This finding indicates that G. lucidum has some antineuraminidase activity against NDV and may be exploited in the management of NDV infection.
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BU Shamaki, Toxicity Studies and Body Weights Changes in Wistar Rats Following Oral Administration of Methanol Extract From Indigenous Ganoderma Sp.In Nigeria, MOJ Biology and Medicine, 1, 5, 2017. Crossref
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Arginine – an essential amino acid found in Ganoderma species from Northern Nigeria, Savannah Veterinary Journal, 2019. Crossref
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El Sheikha Aly Farag El, Nutritional Profile and Health Benefits of Ganoderma lucidum “Lingzhi, Reishi, or Mannentake” as Functional Foods: Current Scenario and Future Perspectives, Foods, 11, 7, 2022. Crossref
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Zhang Yu, Zhang Guoying, Ling Jianya, Medicinal Fungi with Antiviral Effect, Molecules, 27, 14, 2022. Crossref
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Yang Rui , Dong Shanjun , Luo Jiahao , Ma Feifei , Jiang Wenming , Han Chun-Chao, Research Progress on the Function and Application of Proteins of Edible and Medicinal Mushrooms: A Review , International Journal of Medicinal Mushrooms, 24, 12, 2022. Crossref