Library Subscription: Guest
International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Pancreas Protective Effect of Button Mushroom Agaricus bisporus (J.E. Lange) Imbach (Agaricomycetidae) Extract on Rats with Streptozotocin-Induced Dia betes

Volume 12, Issue 4, 2010, pp. 379-389
DOI: 10.1615/IntJMedMushr.v12.i4.50
Get accessGet access

ABSTRACT

In the present study we describe the effects of hot water extract of the culinary-medicinal button mushroom, Agaricus bisporus, on the symptoms of streptozotocin-induced diabetes in Sprague Dawley rats. A. bisporus extract at the doses of 0, 100, 200, and 400 mg/kg body weight (bw) per day were orally applied to streptozotocin-induced diabetic rats for a period of 7 days after the onset of the diabetes. Food and water intake and body weight were recorded daily. Upon sacrifice, histological studies were performed on pancreas tissues, and biochemical parameters such as glucose, insulin superoxide dismutase, malondialdehyde and catalase were measured of all experimental groups. The serum glucose levels significantly decreased after oral administration at the dose of 400 mg/kg bw per day by 29.68% with A. bisporus extract. Furthermore, the serum insulin levels in the streptozotocin-induced diabetic rats were increased to 78.50% at the extract dose of 400 mg/kg bw per day. Also, catalase activities and malondialdehyde levels decreased to values slightly above the normal animal control. The most obvious and surprising change was, however, the increase in cellularity of the Langerhans islets of the pancreas and their apparent repopulation with beta cells. We conclude that the oral application of high doses of A. bisporus extract may result in decreased severity of streptozotocin-induced diabetes in rat.

CITED BY
  1. De Silva Dilani D., Rapior Sylvie, Hyde Kevin D., Bahkali Ali H., Medicinal mushrooms in prevention and control of diabetes mellitus, Fungal Diversity, 56, 1, 2012. Crossref

  2. Bayramoglu Aysegul, Bayramoglu Gokhan, Senturk Hakan, Lycopene Partially Reverses Symptoms of Diabetes in Rats with Streptozotocin-Induced Diabetes, Journal of Medicinal Food, 16, 2, 2013. Crossref

  3. Smiderle Fhernanda R., Alquini Giovana, Tadra-Sfeir Michelle Z., Iacomini Marcello, Wichers Harry J., Van Griensven Leo J.L.D., Agaricus bisporus and Agaricus brasiliensis (1→6)-β-d-glucans show immunostimulatory activity on human THP-1 derived macrophages, Carbohydrate Polymers, 94, 1, 2013. Crossref

  4. Bayramoglu Gokhan, Senturk Hakan, Bayramoglu Aysegul, Uyanoglu Mustafa, Colak Suat, Ozmen Ayse, Kolankaya Durdane, Carvacrol partially reverses symptoms of diabetes in STZ-induced diabetic rats, Cytotechnology, 66, 2, 2014. Crossref

  5. Jayasuriya W. J. A. Banukie N., Wanigatunge Chandanie A., Fernando Gita H., Abeytunga D. Thusitha U., Suresh T. Sugandhika, Hypoglycaemic Activity of CulinaryPleurotus ostreatusandP.cystidiosusMushrooms in Healthy Volunteers and Type 2 Diabetic Patients on Diet Control and the Possible Mechanisms of Action, Phytotherapy Research, 29, 2, 2015. Crossref

  6. Gargano Maria Letizia, van Griensven Leo J. L. D., Isikhuemhen Omoanghe S., Lindequist Ulrike, Venturella Giuseppe, Wasser Solomon P., Zervakis Georgios I., Medicinal mushrooms: Valuable biological resources of high exploitation potential, Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology, 151, 3, 2017. Crossref

  7. Smiderle Fhernanda R., Sassaki Guilherme L., Arkel Jeroen van, Iacomini Marcello, Wichers Harry J., Griensven Leo J.L.D. Van, High Molecular Weight Glucan of the Culinary Medicinal Mushroom Agaricus bisporus is an α-Glucan that Forms Complexes with Low Molecular Weight Galactan, Molecules, 15, 8, 2010. Crossref

  8. Badalyan Susanna M., Barkhudaryan Anush, Rapior Sylvie, Recent Progress in Research on the Pharmacological Potential of Mushrooms and Prospects for Their Clinical Application, in Medicinal Mushrooms, 2019. Crossref

  9. Hyde Kevin D., Xu Jianchu, Rapior Sylvie, Jeewon Rajesh, Lumyong Saisamorn, Niego Allen Grace T., Abeywickrama Pranami D., Aluthmuhandiram Janith V. S., Brahamanage Rashika S., Brooks Siraprapa, Chaiyasen Amornrat, Chethana K. W. Thilini, Chomnunti Putarak, Chepkirui Clara, Chuankid Boontiya, de Silva Nimali I., Doilom Mingkwan, Faulds Craig, Gentekaki Eleni, Gopalan Venkat, Kakumyan Pattana, Harishchandra Dulanjalee, Hemachandran Hridya, Hongsanan Sinang, Karunarathna Anuruddha, Karunarathna Samantha C., Khan Sehroon, Kumla Jaturong, Jayawardena Ruvishika S., Liu Jian-Kui, Liu Ningguo, Luangharn Thatsanee, Macabeo Allan Patrick G., Marasinghe Diana S., Meeks Dan, Mortimer Peter E., Mueller Peter, Nadir Sadia, Nataraja Karaba N., Nontachaiyapoom Sureeporn, O’Brien Meghan, Penkhrue Watsana, Phukhamsakda Chayanard, Ramanan Uma Shaanker, Rathnayaka Achala R., Sadaba Resurreccion B., Sandargo Birthe, Samarakoon Binu C., Tennakoon Danushka S., Siva Ramamoorthy, Sriprom Wasan, Suryanarayanan T. S., Sujarit Kanaporn, Suwannarach Nakarin, Suwunwong Thitipone, Thongbai Benjarong, Thongklang Naritsada, Wei Deping, Wijesinghe S. Nuwanthika, Winiski Jake, Yan Jiye, Yasanthika Erandi, Stadler Marc, The amazing potential of fungi: 50 ways we can exploit fungi industrially, Fungal Diversity, 97, 1, 2019. Crossref

  10. Antonceva Ekaterina, Shamtsyan Mark, Shamtsyan M., Ignateva S., Antidiabetical and hypoglycemic action of mushroom polysaccharides, E3S Web of Conferences, 215, 2020. Crossref

  11. Ahmed Osama M., Ebaid Hossam, El-Nahass El-Shaymaa, Ragab Mahmoud, Alhazza Ibrahim M., Nephroprotective Effect of Pleurotus ostreatus and Agaricus bisporus Extracts and Carvedilol on Ethylene Glycol-Induced Urolithiasis: Roles of NF-κB, p53, Bcl-2, Bax and Bak, Biomolecules, 10, 9, 2020. Crossref

  12. Smiderle Fhernanda R, Ruthes Andrea C, van Arkel Jeroen, Chanput Wasaporn, Iacomini Marcello, Wichers Harry J, Van Griensven Leo JLD, Polysaccharides from Agaricus bisporus and Agaricus brasiliensis show similarities in their structures and their immunomodulatory effects on human monocytic THP-1 cells, BMC Complementary and Alternative Medicine, 11, 1, 2011. Crossref

  13. Dimopoulou Maria, Kolonas Alexandros, Mourtakos Stamatis, Androutsos Odysseas, Gortzi Olga, Nutritional Composition and Biological Properties of Sixteen Edible Mushroom Species, Applied Sciences, 12, 16, 2022. Crossref

1474 Article views 42 Article downloads Metrics
1474 VIEWS 42 DOWNLOADS 13 Crossref CITATIONS Google
Scholar
CITATIONS

Articles with similar content:

The Medicinal Cracked-Cap Polypore Mushroom Phellinus rimosus (Higher Basidiomycetes) Attenuates Alloxan-Induced Hyperglycemia and Oxidative Stress in Rats International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 3
Thekkuttuparambil Ananthanarayanan Ajith, Kainoor Krishnankutty Janardhanan, Kuttikkadan A. Rony, John Mathew
The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)−Induced Oxidative Stress and Hepatic Damage in Mice Journal of Environmental Pathology, Toxicology and Oncology, Vol.36, 2017, issue 4
Mohammad Iqbal, Nurul Amzar
Antidiabetic Properties of the Tiger's Milk Medicinal Mushroom, Lignosus rhinocerotis (Agaricomycetes), in Streptozotocin-Induced Diabetic Rats International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 7
Szu-Ting Ng, Cheng Fhai Chow, Chon-Seng Tan, Kar Lin Nyam
The Black Truffle, Tuber melanosporum (Ascomycetes), Ameliorates Hyperglycemia and Regulates Insulin Signaling Pathway in STZ-Induced Diabetic Rats International Journal of Medicinal Mushrooms, Vol.22, 2020, issue 11
Kumar Ganesan, Baojun Xu , Tongze Zhang, Muthukumaran Jayachandran
Effects of Black Hoof Medicinal Mushroom, Phellinus linteus (Agaricomycetes), Polysaccharide Extract in Streptozotocin-Induced Diabetic Rats International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 4
Gokhan Bayramoglu, Leonardus Johannes Lambertus Donatus Van Griensven, Mustafa Yamaç, Hakan Senturk, Gungor Kanbak, Aysegul Oglakci, Melih Zeytinoglu, Kazim Kartkaya
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections Prices and Subscription Policies Begell House Contact Us Language English 中文 Русский Português German French Spain