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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Antipox Properties of Fomitopsis officinalis (Vill.: Fr.) Bond. et Singer (Agarikon) from the Pacific Northwest of North America

Volume 7, Issue 3, 2005, pp. 495-506
DOI: 10.1615/IntJMedMushr.v7.i3.60
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ABSTRACT

Polypore mushrooms have been used medicinally for thousands of years. The Greek physician Dioscorides first described the use of Fomitopsis officinalis, a wood conk (or agarikon), as a treatment against consumption in 65 AD. Its use as a topical anti-inflammatory agent also spans millennia. Other wood conks such as Ganoderma lucidum (Ling Chi or Reishi) have had a similarly long history of use in Asia. In the past 20 years, wood conks continue to be carefully explored for their immunomodulating and anticancer properties. More recently, mushrooms, including polypores, have been and are being explored for their antimicrobial properties. Of more than 200,000 pharmaceutical and natural products analyzed, and subsequent to the authors’ submitting more than 100 in vitro cultures of mushrooms to the US National Institute of Allergy and Infectious Diseases (NIAID) in coordination with the US National Institute of Health (NIH) and the US Defense Department (DOD)’s Bioshield BioDefense program, several tests show that the author's extracts of cultures originating from rare “old growth” polypore mushrooms demonstrated strong antiviral activity. Within verdant natural landscapes, trees hundreds of years old host ancestral strains of these elusive mushroom species. Species that are now rare, or in some cases thought to be extinct, still reside in the pristine old growth forests of the Pacific Northwest of North America. When clones from these mushrooms were grown in vitro and submitted for antiviral screening, several mycelial cultures produced antimicrobial agents effective against pox and other viruses. Notably, strains vary in their antiviral properties. Our mushroom genomes hold within them great potentials for staving off disease and barely have been explored. The fungal diversity within these genomes may prove critical for isolating the most active strains, similar to the lessons learned from the isolation of Penicillium chrysogenum strains that lead to the commercialization of penicillin, subsequently saving millions of lives. With deforestation, pollution, and industrialization, societies should reevaluate the importance of their natural forests in the context that they hold within them novel medicines of enormous socioeconomic and national defense importance.

CITED BY
  1. Stamets Paul E., Naeger Nicholas L., Evans Jay D., Han Jennifer O., Hopkins Brandon K., Lopez Dawn, Moershel Henry M., Nally Regan, Sumerlin David, Taylor Alex W., Carris Lori M., Sheppard Walter S., Extracts of Polypore Mushroom Mycelia Reduce Viruses in Honey Bees, Scientific Reports, 8, 1, 2018. Crossref

  2. Teplyakova T. V., Bulychev L. E., Kosogova T. A., Ibragimova Zh. B., Yurganova I. A., Kabanov A. S., Puchkova L. I., Bormotov N. I., Bardasheva A. V., Antiviral Activity of Extracts from Basidiomycetes for Orthopoxviruses, Problems of Particularly Dangerous Infections, 3(113), 2012. Crossref

  3. Muszyńska Bożena, Fijałkowska Agata, Sułkowska‐Ziaja Katarzyna, Włodarczyk Anna, Kaczmarczyk Piotr, Nogaj Ewa, Piętka Jacek, Fomitopsis officinalis : a Species of Arboreal Mushroom with Promising Biological and Medicinal Properties , Chemistry & Biodiversity, 17, 6, 2020. Crossref

  4. Fijałkowska Agata, Muszyńska Bożena, Sułkowska-Ziaja Katarzyna, Kała Katarzyna, Pawlik Anna, Stefaniuk Dawid, Matuszewska Anna, Piska Kamil, Pękala Elżbieta, Kaczmarczyk Piotr, Piętka Jacek, Jaszek Magdalena, Medicinal potential of mycelium and fruiting bodies of an arboreal mushroom Fomitopsis officinalis in therapy of lifestyle diseases, Scientific Reports, 10, 1, 2020. Crossref

  5. Blanchette Robert A., Haynes Deborah Tear, Held Benjamin W., Niemann Jonas, Wales Nathan, Fungal mycelial mats used as textile by indigenous people of North America, Mycologia, 113, 2, 2021. Crossref

  6. Hwang Chang Hwa, Jaki Birgit U., Klein Larry L., Lankin David C., McAlpine James B., Napolitano José G., Fryling Nicole A., Franzblau Scott G., Cho Sang Hyun, Stamets Paul E., Wang Yuehong, Pauli Guido F., Chlorinated Coumarins from the Polypore Mushroom Fomitopsis officinalis and Their Activity against Mycobacterium tuberculosis, Journal of Natural Products, 76, 10, 2013. Crossref

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