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ISSN Print: 1521-9437
ISSN Online: 1940-4344
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Improvement of Antibacterial Activity of Red Belt Conk Medicinal Mushroom, Fomitopsis pinicola BCC58 (Agaricomycetes), in Fermentation of Lignocellulosic Materials
ABSTRACT
In this study, the antibacterial activity (ABA) of Fomitopsis pinicola BCC58 was evaluated depending on different cultivation conditions. Xylose and glucose followed by cellobiose ensured the highest inhibition of Staphylococcus aureus (74%-97%) and Escherichia coli (51%-80%) growth. Among lignocellulosic materials tested during submerged and solid-state fermentation, the strongest inhibition activity was revealed after fungus growth in the presence of mandarin squeeze. Mandarin squeeze represents an excellent growth substrate for mushroom, increasing the growth inhibition of E. coli and S. aureus by 90-91%, but supplementation of KNO3 or yeast extract favored the increase of ABA. After cultivation in a 7-L fermenter, ethanolic extracts from F. pinicola BCC58 biomass and culture liquid showed the highest ABA, especially against E. coli, with a minimum inhibitory concentration (MIC) of 0.5 mg/mL. Hot water extract from biomass and ethyl acetate extract from culture liquid showed the lowest ABA against E. coli and S. aureus, with an MIC of 15 and 20 mg/mL and 7.5 and 6.0 mg/mL, respectively.
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Wasser SP. Medicinal mushrooms in human clinical studies. Part I. Anticancer, oncoimmunological, and immunomodulatory activities: A review. Int J Med Mushrooms. 2017;19:279-317.
-
Chang ST, Wasser SP. Current and future research trends in agricultural and biomedical applications of medicinal mushrooms and mushroom products (review). Int J Med Mushrooms. 2018;20:1121-33.
-
Alves MJ, Ferreira IC, Dias J, Teixeira V, Martins A, Pintado M. A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds. Planta Med. 2012;78:1707-18.
-
Gargano ML, van Griensven LJL, Isikhuemhen OS, Lindequist U, Venturella G, Wasser SP, Zervakis GI. Medicinal mushrooms: Valuable biological resources of high exploitation potential. Plant Biosyst. 2017;151:548-65.
-
Rai MK, Gaikwad S, Nagaonkar D, dos Santos CA. Current advances in the antimicrobial potential of species of genus Ganoderma (higher Basidiomycetes) against human pathogenic microorganisms (review). Int J Med Mushrooms. 2015;17:921-32.
-
Cilerdzic J, Kosanic M, Stajic M, Vukojevic J, Rankovic B. Species of genus Ganoderma (Agaricomycetes) fermentation broth: A novel antioxidant and antimicrobial agent. Int J Med Mushrooms. 2016;18:397-404.
-
Suay I, Arenal F, Asensio FJ, Basilio A, Cabello MA, D^ez MT, Garda JB, Gonzalez del Val A, Gorrochategui J, Hernandez P, Pelaez F, Vicente MF. Screening Basidiomycetes for antimicrobial activities. A Van Leeuw J. 2000;78:129-39.
-
Rosa LH, Gomes Machado KM, Jacob CC, Capelari M, Rosa CA, Zani CL. Screening of Brazilian Basidiomycetes for antimicrobial activity. Mem Inst Oswaldo Cruz. 2003;98:967-74.
-
Barros L, Calhelha RC, Vaz JA, Ferreira ICFR, Baptista P, Estevinho LM. Antimicrobial activity and bioactive compounds of Portuguese wild edible mushrooms methanolic extracts. Eur Food Res Technol. 2007;225:151-6.
-
Aqueveque P, Anke T, Saez K, Silva M, Becerra J. Antimicrobial activity of submerged cultures of Chilean Basidiomycetes. Planta Med. 2010;76:1787-91.
-
Rosenberger MG, Paulert R, Cortez VG. Studies of the antimicrobial activity of mushrooms (Agaricales) from South America. Int J Med Mushrooms. 2018;20:1065-74.
-
Turlo J. The biotechnology of higher fungi - current state and perspectives. Folia Biol Oecolog. 2014;10:49-65.
-
Dighe S, Agate AD. Antibacterial activity of some Indian mushrooms. Int J Med Mushrooms. 2000;2:1-10.
-
Dresch P, D'Agunno MN, Rosam K, Grienke U, Rollinger JM, Peintner U. Fungal strain matters: Colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus. AMB Express. 2015;5:4-18.
-
Khadhri A, Aouadhi C, Aschi-Smiti S. Screening of bioactive compounds of medicinal mushrooms collected on Tunisian territory. Int J Med Mushrooms. 2017;19:127-35.
-
Meng TX, Ishikawa H, Shimizu K, Ohga S, Kondo R. A glucosylceramide with antimicrobial activity from the edible mushroom Pleurotus citrinopileatus. J Wood Sci. 2012;58:81-6.
-
Reis FS, Barreira JCM, Calhelha RC, van Griensven LJID, Ciric A, Glamoclija J, Sokovic M, Ferreira ICFR. Chemical characterization of the medicinal mushroom Phellinus linteus (Berkeley & Curtis) Teng and contribution of different fractions to its bioactivity. LWT - Food Sci Technol. 2014;58:478-85.
-
Younis AM, Wu FS, El Shikh HH. Antimicrobial activity of extracts of the oyster culinary medicinal mushroom Pleurotus ostreatus (higher Basidiomycetes) and identification of a new antimicrobial compound. Int J Med Mushrooms. 2015;17:579-90.
-
Duvnjak D, Pantic M, Pavlovic V, Nedovic V, Levic S, Matijasevic D, Sknepnek A, Niksic M. Advances in batch culture fermented Coriolus versicolor medicinal mushroom for the production of antibacterial compounds. Innovat Food Sci Emerging Technol. 2016;34:1-8.
-
Krupodorova TA, Barshteyn VY, Zabeida EF, Pokas EV. Antibacterial activity of macromycetes mycelia and culture liquid. Microbiol Biotechnol Lett. 2016;44:246-53.
-
Matijasevic D, Pantic M, Raskovic B, Pavlovic V, Duvnjak D, Sknepnek A, Niksic M. The antibacterial activity of Coriolus versicolor methanol extract and its effect on ultrastructural changes of Staphylococcus aureus and Salmonella enterica. Front Microbiol. 2016;7:1226.
-
Elisashvili V. Submerged cultivation of medicinal mushrooms: Bioprocesses and products (review). Int J Med Mushrooms. 2012;14:211-39.
-
Khardziani T, Metreveli E, Didebulidze K, Elisashvili V. Screening of Georgian medicinal mushrooms for their antibacterial activity and optimization of cultivation conditions for the split gill medicinal mushroom, Schizophyllum commune BCC64. Int J Med Mushrooms. 2020;22:659-69.
-
Cheng JJ, Lin CY, Lur HS, Chen HP, Lu MK. Properties and biological functions of polysaccharides and ethanolic extracts isolated from medicinal fungus, Fomitopsis pinicola. Process Biochem. 2008;43:829-34.
-
Zahid MT, Idrees M, Ying W, Zaki AH, Abdullah I, Haiying B. Review of chemical constituents and pharmacology of brownrot fungus Fomitopsis pinicola. J Nat Sci Res. 2020;10:58-68.
-
Liu XT, Winkler AL, Schwan WR, Volk TJ, Rott M, Monte A. Antibacterial compounds from mushrooms II: Lanostane triterpenoids and an ergostane steroids with activity against Bacillus cereus isolated from Fomitopsis pinicola. Planta Med. 2010;76:464-6.
-
Pala SA, Wani AH, Ganai BA. Antimicrobial potential of some wild macromycetes collected from Kashmir Himalayas. Plant Sci Today. 2019;6:137-46.
-
Elisashvili V, Kachlishvili E, Asatiani MD, Darlington R, Kucharzyk KH. Physiological peculiarities of lignin-modifying enzyme production by the white-rot Basidiomycete Coriolopsis gallica strain BCC 142. Microorganisms. 2017;5:73.
-
Hassegawa RH, Kasuya MCM, Vanetti MCD. Growth and antibacterial activity of Lentinula edodes in liquid media supplemented with agricultural wastes. Electron J Biotechnol. 2005;8:212-7.
-
Vieira GRT, Liebl M, Tavares LBB, Paulert R, Junior AS. Submerged culture conditions for the production of mycelial biomass and antimicrobial metabolites by Polyporus tricholoma Mont. Braz J Microbiol. 2008;39:561-8.
-
Hassan F, Ni S, Becker TL, Kinstedt CM, Abdul-Samad JL, Actis LA, Kennedy MA. Evaluation of the antibacterial activity of 75 mushrooms collected in the vicinity of Oxford, Ohio (USA). Int J Med Mushrooms. 2019;21:131-41.
-
Chiang SS, Wang LT, Chen SY, Mau JL. Antibacterial and anti-inflammatory activities of mycelia of a medicinal mushroom from Taiwan, Taiwanofungus salmoneus (higher Basidiomycetes). Int J Med Mushrooms. 2013:15:39-47.
-
Elisashvili Vladimir, Asatiani Mikheil D., Khardziani Tamar, Rai Mahendra, Natural Antimicrobials from Basidiomycota Mushrooms, in Promising Antimicrobials from Natural Products, 2022. Crossref