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International Journal of Medicinal Mushrooms

Published 12 issues per year

ISSN Print: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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The Cloning, Characterization, and Functional Analysis of a Gene Encoding an Isopentenyl Diphosphate Isomerase Involved in Triterpene Biosynthesis in the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes)

Volume 15, Issue 3, 2013, pp. 223-232
DOI: 10.1615/IntJMedMushr.v15.i3.10
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ABSTRACT

An isopentenyl diphosphate isomerase (IDI) gene, GlIDI, was isolated from Ganoderma lucidum, which produces triterpenes through the mevalonate pathway. The open reading frame of GlIDI encodes a 252 amino acid polypeptide with a theoretical molecular mass of 28.71 kDa and a theoretical isoelectric point of 5.36. GlIDI is highly homologous to other fungal IDIs and contains conserved active residues and nudix motifs shared by the IDI protein family. The color complementation assay indicated that GlIDI can accelerate the accumulation of β-carotene and confirmed that the cloned complementary DNA encoded a functional GlIDI protein. Gene expression analysis showed that the GlIDI transcription level was relatively low in the mycelia and reached a relatively high level in the mushroom primordia. In addition, its expression level could be up-regulated by 254 µM methyl jasmonate. Our results suggest that this enzyme may play an important role in triterpene biosynthesis.

CITED BY
  1. Tong Yuru, Zhang Meng, Su Ping, Zhao Yujun, Wang Xiujuan, Zhang Xianan, Gao Wei, Huang Luqi, Cloning and functional characterization of an isopentenyl diphosphate isomerase gene fromTripterygium wilfordii, Biotechnology and Applied Biochemistry, 63, 6, 2016. Crossref

  2. Sánchez-Pujante P. J., Miras-Moreno B., Soluyanova P., Garre V., Pedreño M. A., Almagro Lorena, Production of fatty acid methyl esters and other bioactive compounds in elicited cultures of the fungus Mucor circinelloides , Mycological Progress, 16, 5, 2017. Crossref

  3. Gu Li, Zheng Yimei, Lian Danhong, Zhong Xin, Liu Xin, Production of triterpenoids from Ganoderma lucidum : Elicitation strategy and signal transduction, Process Biochemistry, 69, 2018. Crossref

  4. Wang Qiong, Xu Mengmeng, Zhao Liting, Wang Feng, Li Youran, Shi Guiyang, Ding Zhongyang, Transcriptome dynamics and metabolite analysis revealed the candidate genes and regulatory mechanism of ganoderic acid biosynthesis during liquid superficial‐static culture of Ganoderma lucidum , Microbial Biotechnology, 14, 2, 2021. Crossref

  5. Liu Jingting, Li Jingling, Jiang Mei, Liu Chang, The Nuclear Genome of Lingzhi Mushroom, in The Lingzhi Mushroom Genome, 2021. Crossref

  6. Ren Ang, Shi Liang, Zhu Jing, Liu Rui, Zhao Mingwen, Biosynthetic Pathway and Signal Transduction Regulation of Ganoderic Acid Biosynthesis in Lingzhi, in The Lingzhi Mushroom Genome, 2021. Crossref

  7. Jana Pradipta, Acharya Krishnendu, Mushroom: A New Resource for Anti-Angiogenic Therapeutics, Food Reviews International, 38, 1, 2022. Crossref

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