Library Subscription: Guest
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections
International Journal of Medicinal Mushrooms
IF: 1.423 5-Year IF: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v1.i2.40
pages 147-152

Studies on the Triterpenoid Constituents of the Spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae)

Ruo-Yun Chen
Department of Chemistry of Natural Products Institute of Materia Medica, Chinese Academy of Medical Science, Beijing, R.P. China
De-Quan Yu
Department of Chemistry of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, 100050, China

ABSTRACT

Five compounds were isolated from the ether-soluble fraction of the spores of Ganoderma lucidum (Curt.: Fr.) P. Karst. On the basis of their chemical properties and spectral data (MS, UV, IR, 1H, and 13C-NMR), they were identified as 3,7,11,12,15,23-hexaoxo-5α-lanosta-8-en-26-oic acid (I); ganoderic acids B (II), C (III), and E (IV); and ganodermanontriol (V). Compound I is a new natural product named ganosporeric acid A. Compounds II, III, IV, and V are known compounds and were obtained for the first time from the spores of G. lucidum. Pharmacological experiments showed that ganosporeric acid A has GPT-lowering activity in mice with liver injury caused by CCI4 and GaNI and exhibits hepaoprotective effects.


Articles with similar content:

p-Terphenyl Compounds Possessing Antioxidative Activity from Japanese Inedible Mushrooms
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Yoshinori Asakawa, Dang Ngoc Quang, Toshihiro Hashimoto
Chemical Composition and Medicinal Value of Fruiting Bodies and Submerged Cultured Mycelia of Caterpillar Medicinal Fungus Cordyceps militaris CBS-132098 (Ascomycetes)
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 7
Solomon P. Wasser, Mikheil D. Asatiani, Gayane S. Barseghyan, Jannie Siew Lee Chan
PPAR-α Agonist Fenofibrate Ameliorates Oxidative Stress in Testicular Tissue of Diabetic Rats
Critical Reviews™ in Eukaryotic Gene Expression, Vol.30, 2020, issue 2
Tannaz Jamialahmadi, Habib Yaribeygi, Mohammad Taghi Mohammadi, Amirhossein Sahebkar
Histopathological, Enzymatic, and Molecular Alterations Induced By Cigarette Smoke Inhalation in the Pulmonary Tissue of Mice and Its Amelioration By Aqueous Azadirachta Indica Leaf Extract
Journal of Environmental Pathology, Toxicology and Oncology, Vol.31, 2012, issue 1
Ashwani Koul, Sanjay Bharati, Neha Kapoor
Antioxidant Activity of Different Fractions of Methanolic Extract of the Golden Chanterelle Mushroom Cantharellus cibarius (Higher Basidiomycetes) from Iran
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 6
Masoumeh Khalili, Yaghoub Safdari, Mohammad Ali Ebrahimzadeh