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International Journal of Medicinal Mushrooms

Impact factor: 1.357

ISSN Print: 1521-9437
ISSN Online: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v3.i4.90
3 pages

Hypocholesterolemic Activity of the Genus Pleurotus (Jacq.: Fr.) P. Kumm. (Agaricales s. I., Basidiomycetes)

Nina Gunde-Cimerman
Department for Biotechnology and Industrial Mycology, National Institute of Chemistry, Hajdzihova 19, 1000 Ljubljana; University of Ljubljana, Biotechnical Faculty, Department of Biology, Vecna pot 111,1000 Ljubljana, Slovenia
Ana Plemenitas
University of Ljubljana, Medical Faculty, Institute of Biochemistry, Vrazov trg 2, 1000 Ljubljana, Slovenia


Pleurotus species, especially P. ostreatus (Jacq: Fr.) Kumm., popularly named the oyster mushroom, are prime edible mushrooms that are commercially cultivated. It is known that, owing to their high protein content and dietary fibers these mushrooms have a positive effect on human nutrition. Besides, Pleurotus spp. modulate the immune system; have hypoglycemic activity; have an antithrombotic effect; inhibit tumor growth, inflammation, and microbial action; and lower blood pressure and plasma lipid concentration. In addition, they effectively reduce lipids in general and specifically low-density lipoprotein (LDL) cholesterol.