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Critical Reviews™ in Physical and Rehabilitation Medicine
SJR: 0.117 SNIP: 0.228 CiteScore™: 0.17

ISSN Print: 0896-2960
ISSN Online: 2162-6553

Critical Reviews™ in Physical and Rehabilitation Medicine

DOI: 10.1615/CritRevPhysRehabilMed.v7.i2.10
pages 93-112

Nerve Block Therapy and Postherpetic Neuralgia

Kenjiro Dan
Department of Anesthesiology, School of Medicine, Fukuoka University, Fukuoka, Japan

ABSTRACT

This article, which reviews pain therapy in postherpetic neuralgia, is based largely on the treatment of 2,300 Japanese patients with herpes zoster-related pain (80%) and postherpetic neuralgia (20%), with nerve block therapy. In the early stages of herpes zoster, acyclovir and Ara-A plus nerve block therapy were prescribed. Based on 20-years experience, we find that epidural infusion, given on a continuous basis, shortens the duration of pain, minimizes tactile allodynia, and diminishes postherpetic neuralgia. The location of affected primary sensory neurons and putative mechanisms of postherpetic neuralgia are discussed.


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