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Critical Reviews™ in Physical and Rehabilitation Medicine
SJR: 0.121 SNIP: 0.228 CiteScore™: 0.5

ISSN Print: 0896-2960
ISSN Online: 2162-6553

Critical Reviews™ in Physical and Rehabilitation Medicine

DOI: 10.1615/CritRevPhysRehabilMed.v14.i34.40
16 pages

Reflex Sympathetic Dystrophy: A Comprehensive Review

Alex Moroz
Department of Rehabilitation Medicine, New York University School of Medicine, Rusk Institute of Rehabilitation Medicine, 400 E. 34th Street, Room 228, New York, NY 10016
Alex Leali
Department of Orthopedic Surgery, New York University School of Medicine, New York University Medical Center
Mathew Lee
Department of Rehabilitation Medicine, New York University School of Medicine, Rusk Institute of Rehabilitation Medicine
Angela Liu
New York University School of Medicine

ABSTRACT

Reflex sympathetic dystrophy (chronic regional pain syndrome [CRPS], type 1) is a syndrome that usually develops after an initiating noxious event, is not limited to the distribution of a single peripheral nerve, and is apparently disproportionate to the inciting event. It is associated at some point with evidence of edema, changes in skin blood flow, abnormal sudomotor activity in the region of the pain, or allodynia or hyperalgesia. Following a historical review as it relates to evolving theories of etiology and pathogenesis of CRPS, this article reviews evidencebased knowledge that is currently available regarding demographics, diagnosis, treatment, and outcomes after CRPS.


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